Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity DV Bulavin, ON Demidov, S Saito, P Kauraniemi, C Phillips, ... Nature genetics 31 (2), 210-215, 2002 | 533 | 2002 |
Wip1 phosphatase modulates ATM-dependent signaling pathways S Shreeram, ON Demidov, WK Hee, H Yamaguchi, N Onishi, C Kek, ... Molecular cell 23 (5), 757-764, 2006 | 414 | 2006 |
Inhibition of HSP70: a challenging anti-cancer strategy AR Goloudina, ON Demidov, C Garrido Cancer letters 325 (2), 117-124, 2012 | 264 | 2012 |
Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control J Choi, B Nannenga, ON Demidov, DV Bulavin, A Cooney, C Brayton, ... Molecular and Cellular Biology 22 (4), 1094-1105, 2002 | 210 | 2002 |
Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy AL Rérole, J Gobbo, A De Thonel, E Schmitt, JPP de Barros, A Hammann, ... Cancer Research 71 (2), 484-495, 2011 | 187 | 2011 |
Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase S Shreeram, WK Hee, ON Demidov, C Kek, H Yamaguchi, AJ Fornace, ... Journal of Experimental Medicine 203 (13), 2793-2799, 2006 | 157 | 2006 |
ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation R Pedeux, S Sengupta, JC Shen, ON Demidov, S Saito, H Onogi, ... Molecular and cellular biology 25 (15), 6639-6648, 2005 | 157 | 2005 |
Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine ON Demidov, O Timofeev, HNY Lwin, C Kek, E Appella, DV Bulavin Cell stem cell 1 (2), 180-190, 2007 | 126 | 2007 |
The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis ON Demidov, C Kek, S Shreeram, O Timofeev, AJ Fornace, E Appella, ... Oncogene 26 (17), 2502-2506, 2007 | 118 | 2007 |
p38MAPK controls expression of multiple cell cycle inhibitors and islet proliferation with advancing age ESM Wong, X Le Guezennec, ON Demidov, NT Marshall, ST Wang, ... Developmental cell 17 (1), 142-149, 2009 | 116 | 2009 |
Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis GI Belova, O Demidov, AJ Fornace, DV Bulavin Cancer biology & therapy 4 (10), 1154-1158, 2005 | 81 | 2005 |
Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging Y Zhu, ON Demidov, AM Goh, DM Virshup, DP Lane, DV Bulavin The Journal of clinical investigation 124 (7), 3263, 2014 | 79 | 2014 |
Substrate specificity of the human protein phosphatase 2Cδ, Wip1 H Yamaguchi, G Minopoli, ON Demidov, DK Chatterjee, CW Anderson, ... Biochemistry 44 (14), 5285-5294, 2005 | 72 | 2005 |
HSP110 promotes colorectal cancer growth through STAT3 activation K Berthenet, A Lagrange, G Marcion, C Boudesco, S Causse, ... Oncogene, 2016 | 68 | 2016 |
Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation ML Schito, ON Demidov, S Saito, JD Ashwell, E Appella The Journal of Immunology 176 (8), 4818-4825, 2006 | 66 | 2006 |
Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites M Rossi, ON Demidov, CW Anderson, E Appella, SJ Mazur Nucleic acids research 36 (22), 7168-7180, 2008 | 64 | 2008 |
Heat shock proteins in cardiosurgery patients ON Demidov, V Vitalyevich Tyrenko, A Sergeyevich Svistov, ... European journal of cardio-thoracic surgery 16 (4), 444-449, 1999 | 60 | 1999 |
Wip1 Regulates the Generation of New Neural Cells in the Adult Olfactory Bulb through p53‐Dependent Cell Cycle Control YH Zhu, CW Zhang, L Lu, ON Demidov, L Sun, L Yang, DV Bulavin, ... Stem cells 27 (6), 1433-1442, 2009 | 57 | 2009 |
Wip1 phosphatase: between p53 and MAPK kinases pathways AR Goloudina, EY Kochetkova, TV Pospelova, ON Demidov Oncotarget 7 (21), 31563, 2016 | 54 | 2016 |
Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents AR Goloudina, K Tanoue, A Hammann, E Fourmaux, X Le Guezennec, ... Proceedings of the National Academy of Sciences 109 (2), E68-E75, 2012 | 53 | 2012 |