| Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification JP Schouten, CJ McElgunn, R Waaijer, D Zwijnenburg, F Diepvens, ... Nucleic acids research 30 (12), e57-e57, 2002 | 3393 | 2002 |
| The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1266 | 2018 |
| Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes JJ Molenaar, J Koster, DA Zwijnenburg, P Van Sluis, LJ Valentijn, ... Nature 483 (7391), 589-593, 2012 | 931 | 2012 |
| Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations TF Eleveld, DA Oldridge, V Bernard, J Koster, LC Daage, SJ Diskin, ... Nature genetics 47 (8), 864-871, 2015 | 535 | 2015 |
| Neuroblastoma is composed of two super-enhancer-associated differentiation states T Van Groningen, J Koster, LJ Valentijn, DA Zwijnenburg, N Akogul, ... Nature genetics 49 (8), 1261-1266, 2017 | 425 | 2017 |
| TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors LJ Valentijn, J Koster, DA Zwijnenburg, NE Hasselt, P Van Sluis, ... Nature genetics 47 (12), 1411-1414, 2015 | 394 | 2015 |
| A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma T van Groningen, N Akogul, EM Westerhout, A Chan, NE Hasselt, ... Nature communications 10 (1), 1530, 2019 | 132 | 2019 |
| The molecular landscape of ETMR at diagnosis and relapse S Lambo, SN Gröbner, T Rausch, SM Waszak, C Schmidt, A Gorthi, ... Nature 576 (7786), 274-280, 2019 | 118 | 2019 |
| Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion TT Vellinga, S Den Uil, IHB Rinkes, D Marvin, B Ponsioen, ... Oncogene 35 (40), 5263-5271, 2016 | 114 | 2016 |
| OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells J Bunt, NE Hasselt, DA Zwijnenburg, M Hamdi, J Koster, R Versteeg, ... International journal of cancer 131 (2), E21-E32, 2012 | 101 | 2012 |
| Evaluation of the similarity of gene expression data estimated with SAGE and Affymetrix GeneChips F van Ruissen, JM Ruijter, GJ Schaaf, L Asgharnegad, DA Zwijnenburg, ... BMC genomics 6, 1-16, 2005 | 99 | 2005 |
| Silencing of SPRY1 Triggers Complete Regression of Rhabdomyosarcoma Tumors Carrying a Mutated RAS Gene G Schaaf, M Hamdi, D Zwijnenburg, A Lakeman, D Geerts, R Versteeg, ... Cancer research 70 (2), 762-771, 2010 | 80 | 2010 |
| Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours LT Bate-Eya, ME Ebus, J Koster, IJM den Hartog, DA Zwijnenburg, ... European journal of cancer 50 (3), 628-637, 2014 | 73 | 2014 |
| Full transcriptome analysis of rhabdomyosarcoma, normal and fetal skeletal muscle: statistical comparison of multiple SAGE libraries GJ Schaaf, JM Ruijter, F van Ruissen, DA Zwijnenburg, R Waaijer, ... The FASEB journal 19 (3), 1-26, 2005 | 71 | 2005 |
| RAS–MAPK pathway-driven tumor progression is associated with loss of CIC and other genomic aberrations in neuroblastoma TF Eleveld, L Schild, J Koster, DA Zwijnenburg, LK Alles, ME Ebus, ... Cancer research 78 (21), 6297-6307, 2018 | 55 | 2018 |
| Regulation of cell cycle genes and induction of senescence by overexpression of OTX2 in medulloblastoma cell lines J Bunt, TG de Haas, NE Hasselt, DA Zwijnenburg, J Koster, R Versteeg, ... Molecular Cancer Research 8 (10), 1344-1357, 2010 | 51 | 2010 |
| OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels J Bunt, NA Hasselt, DA Zwijnenburg, J Koster, R Versteeg, M Kool Acta neuropathologica 125, 385-394, 2013 | 50 | 2013 |
| The C-terminal region of the Escherichia coli UvrC protein, which is homologous to the C-terminal region of the human ERCC1 protein, is involved in DNA binding and 5′-incision GF Moolenaar, RS Uiterkamp, DA Zwijnenburg, N Goosen Nucleic acids research 26 (2), 462-468, 1998 | 41 | 1998 |
| R2: Genomics analysis and visualization platform J Koster, R Volckmann, D Zwijnenburg, P Molenaar, R Versteeg Cancer Research 79 (13_Supplement), 2490-2490, 2019 | 39 | 2019 |
| Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma J Bunt, NE Hasselt, DA Zwijnenburg, J Koster, R Versteeg, M Kool PloS one 6 (10), e26058, 2011 | 39 | 2011 |
Jan KosterGroupleader Bioinformatics, AUMC, location AMCVerified email at amsterdamumc.nl
