Florian Uhlitz
Florian Uhlitz
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Perturbation-response genes reveal signaling footprints in cancer gene expression
M Schubert, B Klinger, M Klünemann, A Sieber, F Uhlitz, S Sauer, ...
Nature communications 9 (1), 20, 2018
A compendium of ERK targets
EB Ünal, F Uhlitz, N Blüthgen
FEBS letters 591 (17), 2607-2615, 2017
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma
P Bischoff, A Trinks, B Obermayer, JP Pett, J Wiederspahn, F Uhlitz, ...
Oncogene 40 (50), 6748-6758, 2021
Ovarian cancer mutational processes drive site-specific immune evasion
I Vázquez-García, F Uhlitz, N Ceglia, JLP Lim, M Wu, N Mohibullah, ...
Nature, 1-9, 2022
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
R Brandt, T Sell, M Lüthen, F Uhlitz, B Klinger, P Riemer, ...
Nature Communications 10 (1), 2919, 2019
Single-cell genomic variation induced by mutational processes in cancer
T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ...
Nature, 1-10, 2022
Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
F Uhlitz, P Bischoff, S Peidli, A Sieber, A Trinks, M Lüthen, B Obermayer, ...
EMBO molecular medicine 13 (10), e14123, 2021
An immediate–late gene expression module decodes ERK signal duration
F Uhlitz, A Sieber, E Wyler, R Fritsche‐Guenther, J Meisig, M Landthaler, ...
Molecular systems biology 13 (5), 928, 2017
SFPQ depletion is synthetically lethal with BRAFV600E in colorectal cancer cells
K Klotz-Noack, B Klinger, M Rivera, N Bublitz, F Uhlitz, P Riemer, ...
Cell reports 32 (12), 2020
Mutation-specific effects of NRAS oncogenes in colorectal cancer cells
N Kuhn, B Klinger, F Uhlitz, A Sieber, M Rivera, K Klotz-Noack, I Fichtner, ...
Advances in Biological Regulation 79, 100778, 2021
Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector
N Ceglia, Z Sethna, SS Freeman, F Uhlitz, V Bojilova, N Rusk, B Burman, ...
Nature Communications 14 (1), 4400, 2023
Rejuvenating dysfunctional T cells in ovarian cancer: CD28 is the license to kill
F Uhlitz, D Zamarin
Cancer Cell 39 (12), 1567-1569, 2021
Abstract PR012: Evolutionary dynamics of whole-genome doubling in ovarian cancer
I Vázquez-García, M Myers, MJ Williams, SS Freeman, J Li, H Shi, ...
Cancer Research 84 (3_Supplement_2), PR012-PR012, 2024
Targeted Perturb-seq Reveals EGR1 and FOS as Key Regulators of the Transcriptional RAF-MAPK Response
G El Kassem, A Sieber, B Klinger, F Uhlitz, D Steinbrecht, M van Bentum, ...
bioRxiv, 2024.01. 13.575500, 2024
Transient chromosomal instability as a driver of ovarian cancer genome evolution
I Vazquez-Garcia, F Uhlitz, MJ Williams, J Li, H Shi, S Freeman, M Myers, ...
Cancer Research 83 (7_Supplement), 102-102, 2023
EP299/# 232 Genomic instability as a determinant of immune escape in ovarian cancer
I Vazquez-Garcia, F Uhlitz, N Ceglia, J Lim, M Wu, N Mohibullah, ...
International Journal of Gynecological Cancer 32 (Suppl 3), A174-A174, 2022
Abstract LB049: Spatial immune determinants of ICB response in STK11-mutated non-small cell lung cancer
F Uhlitz, D Linn, EB Krall, J Egger, H Rizvi, J Chang, B Nicholson, ...
Cancer Research 82 (12_Supplement), LB049-LB049, 2022
Vector Representation of Gene Co-expression in Single Cell RNA-Seq
N Ceglia, F Uhlitz, A McPherson
EasyChair, 2020
Single cell analysis of colorectal cancer identifies mitogen-activated protein kinase as a key driver of tumor cell plasticity
F Uhlitz, P Bischoff, S Peidli, A Sieber, B Obermayer, E Blanc, A Trinks, ...
bioRxiv, 2020.01. 10.901579, 2020
ERK signal duration decoding by mRNA dynamics
FS Uhlitz
Humboldt-Universität zu Berlin, 2019
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