Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood A Raue, C Kreutz, T Maiwald, J Bachmann, M Schilling, U Klingmüller, ... Bioinformatics 25 (15), 1923-1929, 2009 | 1511 | 2009 |
Lessons learned from quantitative dynamical modeling in systems biology A Raue, M Schilling, J Bachmann, A Matteson, M Schelke, D Kaschek, ... PloS one 8 (9), e74335, 2013 | 409 | 2013 |
Systems biology: experimental design C Kreutz, J Timmer The FEBS journal 276 (4), 923-942, 2009 | 312 | 2009 |
Genome-wide analysis of DNA copy number changes and LOH in CLL using high-density SNP arrays D Pfeifer, M Pantic, I Skatulla, J Rawluk, C Kreutz, UM Martens, P Fisch, ... Blood 109 (3), 1202-1210, 2007 | 278 | 2007 |
Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ... Bioinformatics 31 (21), 3558-3560, 2015 | 262 | 2015 |
Data-based identifiability analysis of non-linear dynamical models S Hengl, C Kreutz, J Timmer, T Maiwald bioinformatics 23 (19), 2612-2618, 2007 | 253 | 2007 |
Addressing parameter identifiability by model-based experimentation A Raue, C Kreutz, T Maiwald, U Klingmüller, J Timmer IET systems biology 5 (2), 120-130, 2011 | 213 | 2011 |
USP 18 lack in microglia causes destructive interferonopathy of the mouse brain T Goldmann, N Zeller, J Raasch, K Kierdorf, K Frenzel, L Ketscher, ... The EMBO journal 34 (12), 1612-1629, 2015 | 207 | 2015 |
Profile likelihood in systems biology C Kreutz, A Raue, D Kaschek, J Timmer The FEBS journal 280 (11), 2564-2571, 2013 | 199 | 2013 |
Joining forces of Bayesian and frequentist methodology: a study for inference in the presence of non-identifiability A Raue, C Kreutz, FJ Theis, J Timmer Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2013 | 166 | 2013 |
Likelihood based observability analysis and confidence intervals for predictions of dynamic models C Kreutz, A Raue, J Timmer BMC Systems Biology 6, 1-9, 2012 | 160 | 2012 |
Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range J Bachmann, A Raue, M Schilling, ME Böhm, C Kreutz, D Kaschek, ... Molecular systems biology 7 (1), 516, 2011 | 157 | 2011 |
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways U Klingmüller, A Bauer, S Bohl, PJ Nickel, K Breitkopf, S Dooley, ... IEE Proceedings-Systems Biology 153 (6), 433-447, 2006 | 157 | 2006 |
Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF‐E2 PS Goerttler, C Kreutz, J Donauer, D Faller, T Maiwald, E März, ... British journal of haematology 129 (1), 138-150, 2005 | 141 | 2005 |
An error model for protein quantification C Kreutz, MMB Rodriguez, T Maiwald, M Seidl, HE Blum, L Mohr, ... Bioinformatics 23 (20), 2747-2753, 2007 | 135 | 2007 |
Transcription factors ETF, E2F, and SP‐1 are involved in cytokine‐independent proliferation of murine hepatocytes S Zellmer, W Schmidt‐Heck, P Godoy, H Weng, C Meyer, T Lehmann, ... Hepatology 52 (6), 2127-2136, 2010 | 128 | 2010 |
Driving the model to its limit: profile likelihood based model reduction T Maiwald, H Hass, B Steiert, J Vanlier, R Engesser, A Raue, F Kipkeew, ... PloS one 11 (9), e0162366, 2016 | 103 | 2016 |
Computational processing and error reduction strategies for standardized quantitative data in biological networks M Schilling, T Maiwald, S Bohl, M Kollmann, C Kreutz, J Timmer, ... The FEBS journal 272 (24), 6400-6411, 2005 | 103 | 2005 |
Caspase-3 feeds back on caspase-8, Bid and XIAP in type I Fas signaling in primary mouse hepatocytes KS Ferreira, C Kreutz, S MacNelly, K Neubert, A Haber, M Bogyo, ... Apoptosis 17, 503-515, 2012 | 100 | 2012 |
Theoretical and experimental analysis links isoform‐specific ERK signalling to cell fate decisions M Schilling, T Maiwald, S Hengl, D Winter, C Kreutz, W Kolch, ... Molecular systems biology 5 (1), 334, 2009 | 98 | 2009 |