James A. Wells
James A. Wells
Verified email at ucsf.edu
Title
Cited by
Cited by
Year
A hot spot of binding energy in a hormone-receptor interface
T Clackson, JA Wells
Science 267 (5196), 383-386, 1995
23321995
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
JA Wells, CL McClendon
Nature 450 (7172), 1001-1009, 2007
19642007
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
19522018
High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
BC Cunningham, JA Wells
Science 244 (4908), 1081-1085, 1989
18721989
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
MR Arkin, JA Wells
Nature reviews Drug discovery 3 (4), 301-317, 2004
18272004
Additivity of mutational effects in proteins
JA Wells
Biochemistry 29 (37), 8509-8517, 1990
15991990
Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule
BC Cunningham, M Ultsch, AM De Vos, MG Mulkerrin, KR Clauser, ...
Science 254 (5033), 821-825, 1991
12031991
K-Ras (G12C) inhibitors allosterically control GTP affinity and effector interactions
JM Ostrem, U Peters, ML Sos, JA Wells, KM Shokat
Nature 503 (7477), 548-551, 2013
11852013
Rational design of potent antagonists to the human growth hormone receptor
G Fuh, BC Cunningham, R Fukunaga, S Nagata, DV Goeddel, JA Wells
Science 256 (5064), 1677-1680, 1992
8581992
Small-molecule inhibitors of protein-protein interactions: progressing toward the reality
MR Arkin, Y Tang, JA Wells
Chemistry & biology 21 (9), 1102-1114, 2014
8012014
Dissecting the catalytic triad of a serine protease
P Carter, JA Wells
Nature 332 (6164), 564-568, 1988
7941988
Convergent solutions to binding at a protein-protein interface
WL DeLano, MH Ultsch, JA Wells
Science 287 (5456), 1279-1283, 2000
7582000
Sodium-driven potassium uptake by the plant potassium transporter HKT1 and mutations conferring salt tolerance
F Rubio, W Gassmann, JI Schroeder
Science 270 (5242), 1660-1663, 1995
7501995
Cassette mutagenesis: an efficient method for generation of multiple mutations at defined sites
JA Wells, M Vasser, DB Powers
Gene 34 (2-3), 315-323, 1985
6811985
Comparison of a structural and a functional epitope
BC Cunningham, JA Wells
Journal of molecular biology 234 (3), 554-563, 1993
6271993
Crystal structure at 1.7 resolution of VEGF in complex with domain 2 of the Flt-1 receptor
C Wiesmann, G Fuh, HW Christinger, C Eigenbrot, JA Wells, AM de Vos
Cell 91 (5), 695-704, 1997
6131997
Hormone phage: an enrichment method for variant proteins with altered binding properties
S Bass, R Greene, JA Wells
Proteins: Structure, Function, and Bioinformatics 8 (4), 309-314, 1990
6031990
Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants
LJ Garrard, DJ Henner, S Bass, R Greene, HB Lowman, JA Wells, ...
US Patent 5,750,373, 1998
5911998
Selecting high-affinity binding proteins by monovalent phage display
HB Lowman, SH Bass, N Simpson, JA Wells
Biochemistry 30 (45), 10832-10838, 1991
5801991
[21] Phage display for selection of novel binding peptides
SS Sidhu, HB Lowman, BC Cunningham, JA Wells
Methods in enzymology 328, 333-IN5, 2000
5692000
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