Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties SK Miroshnichenko, OA Patutina, EA Burakova, BP Chelobanov, ... Proceedings of the National Academy of Sciences 116 (4), 1229-1234, 2019 | 78 | 2019 |
Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I O Patutina, N Mironova, E Ryabchikova, N Popova, V Nikolin, V Kaledin, ... Biochimie 93 (4), 689-696, 2011 | 65 | 2011 |
Enhanced inhibition of tumorigenesis using combinations of miRNA-targeted therapeutics S Miroshnichenko, O Patutina Frontiers in pharmacology 10, 453692, 2019 | 58 | 2019 |
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells N Mironova, I Petrushanko, O Patutina, AV Sen’kova, O Simonenko, ... Cell Cycle 12 (13), 2120-2131, 2013 | 56 | 2013 |
miRNases: Novel peptide-oligonucleotide bioconjugates that silence miR-21 in lymphosarcoma cells OA Patutina, EV Bichenkova, SK Miroshnichenko, NL Mironova, ... Biomaterials 122, 163-178, 2017 | 49 | 2017 |
Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency OA Patutina, SK Gaponova, AV Sen’kova, IA Savin, DV Gladkikh, ... Proceedings of the National Academy of Sciences 117 (51), 32370-32379, 2020 | 36 | 2020 |
Heteroleptic Pd (II) and Pt (II) Complexes with Redox-Active Ligands: Synthesis, Structure, and Multimodal Anticancer Mechanism NF Romashev, PA Abramov, IV Bakaev, IS Fomenko, DG Samsonenko, ... Inorganic Chemistry 61 (4), 2105-2118, 2022 | 31 | 2022 |
Peptide-oligonucleotide conjugates exhibiting pyrimidine-X cleavage specificity efficiently silence miRNA target acting synergistically with RNase H OA Patutina, MA Bazhenov, SK Miroshnichenko, NL Mironova, ... Scientific Reports 8 (1), 14990, 2018 | 30 | 2018 |
The siRNA targeted to mdr1b and mdr1a mRNAs in vivosensitizes murine lymphosarcoma to chemotherapy OA Patutina, NL Mironova, NA Popova, VI Kaledin, VP Nikolin, ... BMC cancer 10, 1-11, 2010 | 30 | 2010 |
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment LA Alekseeva, NL Mironova, EV Brenner, AM Kurilshikov, OA Patutina, ... PLoS One 12 (2), e0171988, 2017 | 27 | 2017 |
The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy N Mironova, O Patutina, E Brenner, A Kurilshikov, V Vlassov, M Zenkova Oncotarget 8 (45), 78796, 2017 | 26 | 2017 |
MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy N Mironova, O Patutina, E Brenner, A Kurilshikov, V Vlassov, M Zenkova PLoS One 8 (12), e83482, 2013 | 26 | 2013 |
Catalytic knockdown of miR-21 by artificial ribonuclease: biological performance in tumor model OA Patutina, SK Miroshnichenko, NL Mironova, AV Sen’kova, ... Frontiers in Pharmacology 10, 471835, 2019 | 25 | 2019 |
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model AV Sen'kova, NL Mironova, OA Patutina, VA Mitkevich, OV Markov, ... Biochimie 101, 256-259, 2014 | 20 | 2014 |
Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics OV Markov, AV Filatov, MS Kupryushkin, IV Chernikov, OA Patutina, ... Molecules 25 (16), 3663, 2020 | 15 | 2020 |
Tumoricidal activity of RNase A and DNase I OA Patutina, NL Mironova, EI Ryabchikova, NA Popova, VP Nikolin, ... Acta Naturae (англоязычная версия) 2 (1 (4)), 88-93, 2010 | 15 | 2010 |
The toxic effects of polychemotherapy onto the liver are accelerated by the upregulated MDR of lymphosarcoma AV Sen'kova, NL Mironova, OA Patutina, TA Ageeva, MA Zenkova International Scholarly Research Notices 2012, 2012 | 12 | 2012 |
Dual miRNases for triple incision of miRNA target: design concept and catalytic performance O Patutina, D Chiglintseva, E Bichenkova, S Gaponova, N Mironova, ... Molecules 25 (10), 2459, 2020 | 11 | 2020 |
Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells MS Kupryushkin, AV Filatov, NL Mironova, OA Patutina, IV Chernikov, ... Molecular Therapy-Nucleic Acids 27, 211-226, 2022 | 10 | 2022 |
Inhibition of invasive properties of murine melanoma by bovine pancreatic DNase I in vitro and in vivo LA Alexeeva, OA Patutina, AV Sen’kova, MA Zenkova, NL Mironova Molecular Biology 51, 562-570, 2017 | 10 | 2017 |