Follow
Bryan Mackowiak
Bryan Mackowiak
National Institute on Alcohol Abuse and Alcoholism
Verified email at umaryland.edu
Title
Cited by
Cited by
Year
MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases
X Wang, Y He, B Mackowiak, B Gao
Gut 70 (4), 784-795, 2021
3342021
Mechanisms of xenobiotic receptor activation: Direct vs. indirect
B Mackowiak, H Wang
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (9 …, 2016
1302016
The roles of xenobiotic receptors: beyond chemical disposition
B Mackowiak, J Hodge, S Stern, H Wang
Drug Metabolism and Disposition 46 (9), 1361-1371, 2018
1092018
Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells
D Li, B Mackowiak, TG Brayman, M Mitchell, L Zhang, SM Huang, H Wang
Biochemical pharmacology 98 (1), 190-202, 2015
572015
Identification of modulators that activate the constitutive androstane receptor from the Tox21 10K compound library
C Lynch, B Mackowiak, R Huang, L Li, S Heyward, S Sakamuru, H Wang, ...
Toxicological Sciences 167 (1), 282-292, 2019
322019
Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
J Ma, A Guillot, Z Yang, B Mackowiak, S Hwang, O Park, BJ Peiffer, ...
The Journal of Clinical Investigation 132 (14), 2022
302022
E-selectin-dependent inflammation and lipolysis in adipose tissue exacerbate steatosis-to-NASH progression via S100A8/9
RM Rodrigues, Y He, S Hwang, A Bertola, B Mackowiak, YA Ahmed, ...
Cellular and molecular gastroenterology and hepatology 13 (1), 151-171, 2022
292022
Mechanistic insights of phenobarbital-mediated activation of human but not mouse pregnane X receptor
L Li, MA Welch, Z Li, B Mackowiak, S Heyward, PW Swaan, H Wang
Molecular Pharmacology 96 (3), 345-354, 2019
282019
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression
Y Fu, B Mackowiak, D Feng, H Lu, Y Guan, T Lehner, H Pan, XW Wang, ...
Gut 72 (10), 1942-1958, 2023
202023
Interleukin-20 exacerbates acute hepatitis and bacterial infection by downregulating IκBζ target genes in hepatocytes
Y He, D Feng, S Hwang, B Mackowiak, X Wang, X Xiang, RM Rodrigues, ...
Journal of hepatology 75 (1), 163-176, 2021
202021
Hepatic injury and inflammation alter ethanol metabolism and drinking behavior
T Ren, B Mackowiak, Y Lin, Y Gao, J Niu, B Gao
Food and chemical toxicology 136, 111070, 2020
152020
Ethanol and its nonoxidative metabolites promote acute liver injury by inducing ER stress, adipocyte death, and lipolysis
SH Park, W Seo, MJ Xu, B Mackowiak, Y Lin, Y He, Y Fu, S Hwang, ...
Cellular and molecular gastroenterology and hepatology 15 (2), 281-306, 2023
132023
Molecular basis of metabolism-mediated conversion of PK11195 from an antagonist to an agonist of the constitutive androstane receptor
B Mackowiak, L Li, MA Welch, D Li, JW Jones, S Heyward, MA Kane, ...
Molecular Pharmacology 92 (1), 75-87, 2017
132017
Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies
D Liang, L Li, C Lynch, B Mackowiak, WD Hedrich, Y Ai, Y Yin, S Heyward, ...
European journal of medicinal chemistry 179, 84-99, 2019
122019
Mechanistic Analysis of an Extracellular Signal–Regulated Kinase 2–Interacting Compound That Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress
R Martinez, W Huang, R Samadani, B Mackowiak, G Centola, L Chen, ...
Journal of Pharmacology and Experimental Therapeutics 376 (1), 84-97, 2021
82021
High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis
B Mackowiak, L Li, C Lynch, A Ziman, S Heyward, M Xia, H Wang
Biochemical pharmacology 168, 224-236, 2019
82019
Activation of VIPR1 suppresses hepatocellular carcinoma progression by regulating arginine and pyrimidine metabolism
Y Fu, S Liu, RM Rodrigues, Y Han, C Guo, Z Zhu, Y He, B Mackowiak, ...
International journal of biological sciences 18 (11), 4341, 2022
72022
Alcohol-associated liver disease
B Mackowiak, Y Fu, L Maccioni, B Gao
The Journal of Clinical Investigation 134 (3), 2024
62024
CITCO as an adjuvant facilitates CHOP-based lymphoma treatment in hCAR-transgenic mice
R Kurian, W Hedrich, B Mackowiak, L Li, H Wang
Cells 9 (11), 2520, 2020
52020
High-content analysis of constitutive androstane receptor nuclear translocation
B Mackowiak, H Wang
Nuclear Receptors: Methods and Experimental Protocols, 71-77, 2019
32019
The system can't perform the operation now. Try again later.
Articles 1–20