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Nishant N Vaikath
Nishant N Vaikath
Qatar Biomedical Resarch Institute, HBKU
Verified email at hbku.edu.qa
Title
Cited by
Cited by
Year
Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease
NK Majbour, NN Vaikath, KD Van Dijk, MT Ardah, S Varghese, ...
Molecular neurodegeneration 11, 1-15, 2016
2702016
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
MF Duffy, TJ Collier, JR Patterson, CJ Kemp, KC Luk, MG Tansey, ...
Journal of neuroinflammation 15, 1-18, 2018
2092018
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates
ML Arotcarena, S Dovero, A Prigent, M Bourdenx, S Camus, G Porras, ...
Brain 143 (5), 1462-1475, 2020
1932020
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology
NN Vaikath, NK Majbour, KE Paleologou, MT Ardah, E van Dam, ...
Neurobiology of disease 79, 81-99, 2015
1572015
Longitudinal changes in CSF alpha‐synuclein species reflect Parkinson's disease progression
NK Majbour, NN Vaikath, P Eusebi, D Chiasserini, M Ardah, S Varghese, ...
Movement Disorders 31 (10), 1535-1542, 2016
1232016
Safety and immunogenicity of the α-synuclein active immunotherapeutic PD01A in patients with Parkinson's disease: a randomised, single-blinded, phase 1 trial
D Volc, W Poewe, A Kutzelnigg, P Lührs, C Thun-Hohenstein, ...
The Lancet Neurology 19 (7), 591-600, 2020
1212020
Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration
V Durante, A de Iure, V Loffredo, N Vaikath, M De Risi, S Paciotti, ...
Brain 142 (5), 1365-1385, 2019
1022019
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity
SS Ghanem, NK Majbour, NN Vaikath, MT Ardah, D Erskine, NM Jensen, ...
Proceedings of the National Academy of Sciences 119 (15), e2109617119, 2022
992022
α‐Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies
I van Steenoven, NK Majbour, NN Vaikath, HW Berendse, ...
Movement Disorders 33 (11), 1724-1733, 2018
982018
Skin α-synuclein deposits differ in clinical variants of synucleinopathy: an in vivo study
V Donadio, A Incensi, O El-Agnaf, G Rizzo, N Vaikath, F Del Sorbo, ...
Scientific reports 8 (1), 14246, 2018
932018
Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy
O El-Agnaf, C Overk, E Rockenstein, M Mante, J Florio, A Adame, ...
Neurobiology of disease 104, 85-96, 2017
932017
Detection of oligomers and fibrils of α-synuclein by AIEgen with strong fluorescence
CWT Leung, F Guo, Y Hong, E Zhao, RTK Kwok, NLC Leung, S Chen, ...
Chemical Communications 51 (10), 1866-1869, 2015
852015
Antibodies against alpha‐synuclein: tools and therapies
NN Vaikath, I Hmila, V Gupta, D Erskine, M Ingelsson, OMA El‐Agnaf
Journal of Neurochemistry 150 (5), 612-625, 2019
692019
Anti-aging treatments slow propagation of synucleinopathy by restoring lysosomal function.
K Dong-Kyu, L Hee-Sun, K Ichiro, NV Yhong-Hee, Shim Nishant, ...
Autophagy, 2016
622016
Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
NK Majbour, D Chiasserini, NN Vaikath, P Eusebi, T Tokuda, ...
Scientific reports 7 (1), 40263, 2017
582017
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
JZ Wu, M Ardah, C Haikal, A Svanbergsson, M Diepenbroek, NN Vaikath, ...
Translational neurodegeneration 8, 1-15, 2019
572019
Development of nonviral vectors targeting the brain as a therapeutic approach for Parkinson's disease and other brain disorders
H Javed, SA Menon, KM Al-Mansoori, A Al-Wandi, NK Majbour, MT Ardah, ...
Molecular Therapy 24 (4), 746-758, 2016
502016
CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers
NK Majbour, JO Aasly, E Hustad, MA Thomas, NN Vaikath, N Elkum, ...
Translational neurodegeneration 9, 1-10, 2020
462020
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
M Bourdenx, A Nioche, S Dovero, ML Arotcarena, S Camus, G Porras, ...
Science advances 6 (20), eaaz9165, 2020
442020
Heterogeneity in α‐synuclein subtypes and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease
NN Vaikath, D Erskine, CM Morris, NK Majbour, K Vekrellis, JY Li, ...
Neuropathology and applied neurobiology 45 (6), 597-608, 2019
342019
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