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Stephen W Doughty
Stephen W Doughty
Interim Head of School of Pharmacy, De Montfort University
Verified email at dmu.ac.uk
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Cited by
Cited by
Year
Bioreductive activation of a series of indolequinones by human DT-diaphorase: Structure− activity relationships
RM Phillips, MA Naylor, M Jaffar, SW Doughty, SA Everett, AG Breen, ...
Journal of medicinal chemistry 42 (20), 4071-4080, 1999
911999
Characterization of drug particle surface energetics and Young’s modulus by atomic force microscopy and inverse gas chromatography
M Davies, A Brindley, X Chen, M Marlow, SW Doughty, I Shrubb, ...
Pharmaceutical research 22, 1158-1166, 2005
842005
Prediction of the three-dimensional structure of human interleukin-7 by homology modeling
RT Kroemer, SW Doughty, AJ Robinson, WG Richards
Protein Engineering, Design and Selection 9 (6), 493-498, 1996
661996
Conversion of a non-selective adenosine receptor antagonist into A 3-selective high affinity fluorescent probes using peptide-based linkers
AJ Vernall, LA Stoddart, SJ Briddon, HW Ng, CA Laughton, SW Doughty, ...
Organic & biomolecular chemistry 11 (34), 5673-5682, 2013
542013
Development and validation of decision forest model for estrogen receptor binding prediction of chemicals using large data sets
HW Ng, SW Doughty, H Luo, H Ye, W Ge, W Tong, H Hong
Chemical research in toxicology 28 (12), 2343-2351, 2015
522015
Molecular dynamics simulations of the adenosine A2a receptor: structural stability, sampling, and convergence
HW Ng, CA Laughton, SW Doughty
Journal of chemical information and modeling 53 (5), 1168-1178, 2013
522013
Chemical modification of the naphthoyl 3-position of JWH-015: in search of a fluorescent probe to the cannabinoid CB2 receptor
AS Yates, SW Doughty, DA Kendall, B Kellam
Bioorganic & medicinal chemistry letters 15 (16), 3758-3762, 2005
482005
The changes in surface energetics with relative humidity of carbamazepine and paracetamol as measured by inverse gas chromatography
MR Sunkersett, IM Grimsey, SW Doughty, JC Osborn, P York, RC Rowe
European journal of pharmaceutical sciences 13 (2), 219-225, 2001
462001
Structure‐Based Identification of Aporphines with Selective 5‐HT2A Receptor‐Binding Activity
V Munusamy, BK Yap, MJC Buckle, SW Doughty, LY Chung
Chemical biology & drug design 81 (2), 250-256, 2013
432013
Molecular dynamics simulations of the adenosine A2a receptor in POPC and POPE lipid bilayers: effects of membrane on protein behavior
HW Ng, CA Laughton, SW Doughty
Journal of chemical information and modeling 54 (2), 573-581, 2014
392014
A dual-application poly (dl-lactic-co-glycolic) acid (PLGA)-chitosan composite scaffold for potential use in bone tissue engineering
Y Boukari, O Qutachi, DJ Scurr, AP Morris, SW Doughty, N Billa
Journal of Biomaterials science, Polymer edition 28 (16), 1966-1983, 2017
342017
Chromatographic retention behaviour of n-alkylbenzenes and pentylbenzene structural isomers on porous graphitic carbon and octadecyl-bonded silica studied using molecular …
CI De Matteis, DA Simpson, SW Doughty, MR Euerby, PN Shaw, ...
Journal of Chromatography A 1217 (44), 6987-6993, 2010
332010
Homology modeling of the human 5-HT1A, 5-HT2A, D1, and D2 receptors: model refinement with molecular dynamics simulations and docking evaluation
BK Yap, MJC Buckle, SW Doughty
Journal of molecular modeling 18, 3639-3655, 2012
302012
Binding of the anticancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex
M AbuKhader, J Heap, C De Matteis, B Kellam, SW Doughty, N Minton, ...
Journal of medicinal chemistry 48 (24), 7714-7719, 2005
302005
The application of molecular modelling to the interpretation of inverse gas chromatography data
IM Grimsey, JC Osborn, SW Doughty, P York, RC Rowe
Journal of Chromatography A 969 (1-2), 49-57, 2002
302002
The influence of L-amino acid molecular structure on the phase transition temperature of hydroxypropyl methylcellulose
JC Richardson, CS Foster, SW Doughty, JS Burton, RJ MacRae, ...
Carbohydrate polymers 65 (1), 22-27, 2006
262006
Flavonoids with M1 Muscarinic Acetylcholine Receptor Binding Activity
M Swaminathan, CF Chee, SP Chin, MJC Buckle, NA Rahman, ...
Molecules 19 (7), 8933-8948, 2014
242014
Assessing GPCR homology models constructed from templates of various transmembrane sequence identities: Binding mode prediction and docking enrichment
JSE Loo, AL Emtage, KW Ng, ASJ Yong, SW Doughty
Journal of Molecular Graphics and Modelling 80, 38-47, 2018
232018
A quantitative assessment of inhaled drug particle–pulmonary surfactant interaction by atomic force microscopy
MJ Davies, A Brindley, X Chen, SW Doughty, M Marlow, CJ Roberts
Colloids and Surfaces B: Biointerfaces 73 (1), 97-102, 2009
222009
A molecular mechanism for toxin block in N-type calcium channels.
SW Doughty, FE Blaney, BS Orlek, WG Richards
Protein engineering 11 (2), 95-99, 1998
211998
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