β-Lactam antibiotic resistance: a current structural perspective MS Wilke, AL Lovering, NCJ Strynadka Current opinion in microbiology 8 (5), 525-533, 2005 | 651 | 2005 |
Structural perspective of peptidoglycan biosynthesis and assembly AL Lovering, SS Safadi, NCJ Strynadka Annual review of biochemistry 81 (1), 451-478, 2012 | 395 | 2012 |
Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis AL Lovering, LH De Castro, D Lim, NCJ Strynadka Science 315 (5817), 1402-1405, 2007 | 374 | 2007 |
Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone: Reversed binding orientations in different redox states of the enzyme PR Race, AL Lovering, RM Green, A Ossor, SA White, PF Searle, ... Journal of Biological Chemistry 280 (14), 13256-13264, 2005 | 253 | 2005 |
Mechanistic and structural analysis of a family 31 α-glycosidase and its glycosyl-enzyme intermediate AL Lovering, SS Lee, YW Kim, SG Withers, NCJ Strynadka Journal of Biological Chemistry 280 (3), 2105-2115, 2005 | 220 | 2005 |
Nitroreductase: a prodrug-activating enzyme for cancer gene therapy. PF Searle, MJ Chen, L Hu, PR Race, AL Lovering, JI Grove, C Guise, ... Clinical & Experimental Pharmacology & Physiology 31 (11), 2004 | 148 | 2004 |
Crystal structures of prostaglandin D2 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin AL Lovering, JP Ride, CM Bunce, JC Desmond, SM Cummings, SA White Cancer research 64 (5), 1802-1810, 2004 | 144 | 2004 |
Structural and biochemical identification of a novel bacterial oxidoreductase L Loschi, SJ Brokx, TL Hills, G Zhang, MG Bertero, AL Lovering, ... Journal of Biological Chemistry 279 (48), 50391-50400, 2004 | 140 | 2004 |
The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 Å, 1.8 Å and 2.4 Å resolution AL Lovering, EI Hyde, PF Searle, SA White Journal of molecular biology 309 (1), 203-213, 2001 | 137 | 2001 |
Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system GW Hughes, SCL Hall, CS Laxton, P Sridhar, AH Mahadi, C Hatton, ... Nature microbiology 4 (10), 1692-1705, 2019 | 117 | 2019 |
Structural insights into the anti-methicillin-resistant Staphylococcus aureus (MRSA) activity of ceftobiprole AL Lovering, MC Gretes, SS Safadi, F Danel, L De Castro, MGP Page, ... Journal of Biological Chemistry 287 (38), 32096-32102, 2012 | 112 | 2012 |
Kinetic and structural characterisation of Escherichia coli nitroreductase mutants showing improved efficacy for the prodrug substrate CB1954 PR Race, AL Lovering, SA White, JI Grove, PF Searle, CW Wrighton, ... Journal of molecular biology 368 (2), 481-492, 2007 | 95 | 2007 |
Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn2+, phosphoenolpyruvate, and N-acetylmannosaminitol J Gunawan, D Simard, M Gilbert, AL Lovering, WW Wakarchuk, ... Journal of Biological Chemistry 280 (5), 3555-3563, 2005 | 94 | 2005 |
Generation of Escherichia Coli Nitroreductase Mutants Conferring Improved Cell Sensitization to the Prodrug CB1954 JI Grove, AL Lovering, C Guise, PR Race, CJ Wrighton, SA White, EI Hyde, ... Cancer research 63 (17), 5532-5537, 2003 | 94 | 2003 |
Specialized Peptidoglycan Hydrolases Sculpt the Intra-bacterial Niche of Predatory Bdellovibrio and Increase Population Fitness TR Lerner, AL Lovering, NK Bui, K Uchida, SI Aizawa, W Vollmer, ... Plos pathogens 8 (2), e1002524, 2012 | 90 | 2012 |
The Structure of an Unconventional HD-GYP Protein from Bdellovibrio Reveals the Roles of Conserved Residues in this Class of Cyclic-di-GMP Phosphodiesterases AL Lovering, MJ Capeness, C Lambert, L Hobley, RE Sockett MBio 2 (5), 10.1128/mbio. 00163-11, 2011 | 84* | 2011 |
Expanding the thioglycoligase strategy to the synthesis of α-linked thioglycosides allows structural investigation of the parent enzyme/substrate complex YW Kim, AL Lovering, H Chen, T Kantner, LP McIntosh, NCJ Strynadka, ... Journal of the American Chemical Society 128 (7), 2202-2203, 2006 | 81 | 2006 |
The evolution of new lipoprotein subunits of the bacterial outer membrane BAM complex K Anwari, CT Webb, S Poggio, AJ Perry, M Belousoff, N Celik, G Ramm, ... Molecular microbiology 84 (5), 832-844, 2012 | 76 | 2012 |
Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b LS Gonzalez-Delgado, H Walters-Morgan, B Salamaga, AJ Robertson, ... Nature chemical biology 16 (1), 24-30, 2020 | 65 | 2020 |
Identification of dynamic structural motifs involved in peptidoglycan glycosyltransfer AL Lovering, L De Castro, NCJ Strynadka Journal of molecular biology 383 (1), 167-177, 2008 | 61 | 2008 |