T. Justin Rettenmaier
T. Justin Rettenmaier
Jnana Therapeutics
Verified email at jnanatx.com - Homepage
Cited by
Cited by
Hydride as a leaving group in the reaction of pinacolborane with halides under ambient Grignard and Barbier conditions. One-pot synthesis of alkyl, aryl, heteroaryl, vinyl, and …
JW Clary, TJ Rettenmaier, R Snelling, W Bryks, J Banwell, WT Wipke, ...
The Journal of organic chemistry 76 (23), 9602-9610, 2011
CryptoSite: expanding the druggable proteome by characterization and prediction of cryptic binding sites
P Cimermancic, P Weinkam, TJ Rettenmaier, L Bichmann, DA Keedy, ...
Journal of molecular biology 428 (4), 709-719, 2016
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering
DA Keedy, ZB Hill, JT Biel, E Kang, TJ Rettenmaier, J Brandao-Neto, ...
Elife 7, e36307, 2018
A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1
TJ Rettenmaier, JD Sadowsky, ND Thomsen, SC Chen, AK Doak, ...
Proceedings of the National Academy of Sciences 111 (52), 18590-18595, 2014
Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues
JE Seaman, O Julien, PS Lee, TJ Rettenmaier, ND Thomsen, JA Wells
Cell Death & Differentiation 23 (10), 1717-1726, 2016
FP tethering: a screening technique to rapidly identify compounds that disrupt protein–protein interactions
JM Lodge, TJ Rettenmaier, JA Wells, WC Pomerantz, AK Mapp
MedChemComm 5 (3), 370-375, 2014
Kinase atlas: druggability analysis of potential allosteric sites in kinases
C Yueh, J Rettenmaier, B Xia, DR Hall, A Alekseenko, KA Porter, ...
Journal of medicinal chemistry 62 (14), 6512-6524, 2019
Small-molecule allosteric modulators of the protein kinase PDK1 from structure-based docking
TJ Rettenmaier, H Fan, J Karpiak, A Doak, A Sali, BK Shoichet, JA Wells
Journal of medicinal chemistry 58 (20), 8285-8291, 2015
Identification of a covalent molecular inhibitor of anti-apoptotic BFL-1 by disulfide tethering
EP Harvey, ZJ Hauseman, DT Cohen, TJ Rettenmaier, S Lee, AJ Huhn, ...
Cell chemical biology 27 (6), 647-656. e6, 2020
Site-directed fragment discovery for allostery
TJ Rettenmaier, SA Hudson, JA Wells
Fragment-Based Drug Discovery Lessons and Outlook, 2016
Redox priming promotes Aurora A activation during mitosis
DC Lim, V Joukov, TJ Rettenmaier, A Kumagai, WG Dunphy, JA Wells, ...
Science Signaling 13 (641), 2020
New routes for PTP1B allosteric inhibition by multitemperature crystallography, fragment screening and covalent tethering
DA Keedy, ZB Hill, JT Biel, E Kang, TJ Rettenmaier, J Brandao-Neto, ...
BioRxiv, 218966, 2017
Discovering and Manipulating Protein Conformational Heterogeneity and Function
D Keedy, H van den Bedem, J Rettenmaier, J Wells, J Fraser
Biophysical Journal 106 (2), 635a-636a, 2014
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