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Simone Engelender
Simone Engelender
Verified email at technion.ac.il - Homepage
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Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13162*2021
Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions
S Engelender, Z Kaminsky, X Guo, AH Sharp, RK Amaravi, JJ Kleiderlein, ...
Nature genetics 22 (1), 110-114, 1999
6291999
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation
KL Lim, KCM Chew, JMM Tan, C Wang, KKK Chung, Y Zhang, Y Tanaka, ...
Journal of Neuroscience 25 (8), 2002-2009, 2005
6262005
Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
Y Tanaka, S Engelender, S Igarashi, RK Rao, T Wanner, RE Tanzi, ...
Human molecular genetics 10 (9), 919-926, 2001
6192001
Huntingtin-associated Protein 1 (HAP1) Interacts with the p150Glued Bubunit of Dynactin
S Engelender, AH Sharp, V Colomer, MK Tokito, A Lanahan, P Worley, ...
Human molecular genetics 6 (13), 2205-2212, 1997
4301997
Synphilin‐1 is present in Lewy bodies in Parkinson's disease
K Wakabayashi, S Engelender, M Yoshimoto, S Tsuji, CA Ross, ...
Annals of Neurology: Official Journal of the American Neurological …, 2000
3322000
Monoubiquitylation of α-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells
R Rott, R Szargel, J Haskin, V Shani, A Shainskaya, I Manov, E Liani, ...
Journal of Biological Chemistry 283 (6), 3316-3328, 2008
2442008
Ubiquitylation of synphilin-1 and α-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease
E Liani, A Eyal, E Avraham, R Shemer, R Szargel, D Berg, A Bornemann, ...
Proceedings of the National Academy of Sciences 101 (15), 5500-5505, 2004
2332004
The threshold theory for Parkinson's disease
S Engelender, O Isacson
Trends in neurosciences 40 (1), 4-14, 2017
2122017
α-Synuclein fate is determined by USP9X-regulated monoubiquitination
R Rott, R Szargel, J Haskin, R Bandopadhyay, AJ Lees, V Shani, ...
Proceedings of the National Academy of Sciences 108 (46), 18666-18671, 2011
2072011
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies
H Vicente Miranda, ÉM Szegő, LMA Oliveira, C Breda, E Darendelioglu, ...
Brain 140 (5), 1399-1419, 2017
2022017
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease
FP Marx, C Holzmann, KM Strauss, L Li, O Eberhardt, E Gerhardt, ...
Human molecular genetics 12 (11), 1223-1231, 2003
1912003
Inhibition of creatine kinase by S-nitrosoglutathione
H Wolosker, R Panizzutti, S Engelender
FEBS letters 392 (3), 274-276, 1996
1731996
Human serine racemase: moleular cloning, genomic organization and functional analysis
J De Miranda, A Santoro, S Engelender, H Wolosker
Gene 256 (1-2), 183-188, 2000
1702000
SUMOylation and ubiquitination reciprocally regulate α-synuclein degradation and pathological aggregation
R Rott, R Szargel, V Shani, H Hamza, M Savyon, F Abd Elghani, ...
Proceedings of the National Academy of Sciences 114 (50), 13176-13181, 2017
1612017
Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain
V Colomer, S Engelender, AH Sharp, K Duan, JK Cooper, A Lanahan, ...
Human molecular genetics 6 (9), 1519-1525, 1997
1601997
Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation
E Avraham, R Rott, E Liani, R Szargel, S Engelender
Journal of Biological Chemistry 282 (17), 12842-12850, 2007
1522007
Ubiquitination of α-synuclein and autophagy in Parkinson's disease
S Engelender
Autophagy 4 (3), 372-374, 2008
1512008
Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by α-synuclein
CS Ribeiro, K Carneiro, CA Ross, JRL Menezes, S Engelender
Journal of Biological Chemistry 277 (26), 23927-23933, 2002
1432002
The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway
R Szargel, V Shani, F Abd Elghani, LN Mekies, E Liani, R Rott, ...
Human molecular genetics 25 (16), 3476-3490, 2016
1332016
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