| The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains J Hughes, CJ Ward, B Peral, R Aspinwall, K Clark, JL San Millán, ... Nature genetics 10 (2), 151-160, 1995 | 1050 | 1995 |
| The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16 European Polycystic Kidney Disease Consortium Cell 77 (6), 881-894, 1994 | 776 | 1994 |
| Deletion of the TSC2 and PKD1 genes associated with severe infantile polycystic kidney disease — a contiguous gene syndrome PT Brook-Carter, B Peral, CJ Ward, P Thompson, J Hughes, ... Nature genetics 8 (4), 328-332, 1994 | 554 | 1994 |
| Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment JR Hughes, N Roberts, S McGowan, D Hay, E Giannoulatou, M Lynch, ... Nature genetics 46 (2), 205-212, 2014 | 514 | 2014 |
| ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner MJ Law, KM Lower, HPJ Voon, JR Hughes, D Garrick, V Viprakasit, ... Cell 143 (3), 367-378, 2010 | 459 | 2010 |
| Genetic dissection of the α-globin super-enhancer in vivo D Hay, JR Hughes, C Babbs, JOJ Davies, BJ Graham, LLP Hanssen, ... Nature genetics 48 (8), 895-903, 2016 | 367 | 2016 |
| A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter M De Gobbi, V Viprakasit, JR Hughes, C Fisher, VJ Buckle, H Ayyub, ... Science 312 (5777), 1215-1217, 2006 | 361 | 2006 |
| A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition EA Traxler, Y Yao, YD Wang, KJ Woodard, R Kurita, Y Nakamura, ... Nature medicine 22 (9), 987-990, 2016 | 349 | 2016 |
| Intragenic enhancers act as alternative promoters MS Kowalczyk, JR Hughes, D Garrick, MD Lynch, JA Sharpe, ... Molecular cell 45 (4), 447-458, 2012 | 313 | 2012 |
| Association between active genes occurs at nuclear speckles and is modulated by chromatin environment JM Brown, J Green, RP das Neves, HAC Wallace, AJH Smith, J Hughes, ... The Journal of cell biology 182 (6), 1083-1097, 2008 | 301 | 2008 |
| Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study RA Evans, OC Leavy, M Richardson, O Elneima, HJC McAuley, ... The Lancet Respiratory Medicine 10 (8), 761-775, 2022 | 286 | 2022 |
| Multiplexed analysis of chromosome conformation at vastly improved sensitivity JOJ Davies, JM Telenius, SJ McGowan, NA Roberts, S Taylor, DR Higgs, ... Nature methods 13 (1), 74, 2016 | 277 | 2016 |
| Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA‐1 and GATA‐2 E Anguita, J Hughes, C Heyworth, GA Blobel, WG Wood, DR Higgs The EMBO journal 23 (14), 2841-2852, 2004 | 263 | 2004 |
| Unlinking an lncRNA from its associated cis element VR Paralkar, CC Taborda, P Huang, Y Yao, AV Kossenkov, R Prasad, ... Molecular cell 62 (1), 104-110, 2016 | 251 | 2016 |
| An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment MD Lynch, AJH Smith, M De Gobbi, M Flenley, JR Hughes, D Vernimmen, ... The EMBO journal 31 (2), 317-329, 2012 | 233 | 2012 |
| Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells MT Kassouf, JR Hughes, S Taylor, SJ McGowan, S Soneji, AL Green, ... Genome research 20 (8), 1064-1083, 2010 | 222 | 2010 |
| Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo LLP Hanssen, MT Kassouf, AM Oudelaar, D Biggs, C Preece, DJ Downes, ... Nature cell biology 19 (8), 952-961, 2017 | 213 | 2017 |
| Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence HAC Wallace, F Marques-Kranc, M Richardson, F Luna-Crespo, ... Cell 128 (1), 197-209, 2007 | 206 | 2007 |
| Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains R Sandford, B Sgotto, S Aparicio, S Brenner, M Vaudin, RK Wilson, ... Human molecular genetics 6 (9), 1483-1489, 1997 | 189 | 1997 |
| A pseudo top-hat mathematical morphological approach to edge detection in dark regions T Chen, QH Wu, R Rahmani-Torkaman, J Hughes Pattern Recognition 35 (1), 199-210, 2002 | 187 | 2002 |
