| Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms Q Yang, M Li, OB Spiller, DO Andrey, P Hinchliffe, H Li, C MacLean, ... Nature communications 8 (1), 2054, 2017 | 167 | 2017 |
| Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides LC Powell, MF Pritchard, EL Ferguson, KA Powell, SU Patel, PD Rye, ... npj Biofilms and Microbiomes 4 (1), 13, 2018 | 147 | 2018 |
| A new class of safe oligosaccharide polymer therapy to modify the mucus barrier of chronic respiratory disease MF Pritchard, LC Powell, GE Menzies, PD Lewis, K Hawkins, C Wright, ... Molecular Pharmaceutics 13 (3), 863-872, 2016 | 83 | 2016 |
| Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus spp A Tøndervik, H Sletta, G Klinkenberg, C Emanuel, LC Powell, ... PLoS One 9 (11), e112518, 2014 | 83 | 2014 |
| Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus spp A Tøndervik, H Sletta, G Klinkenberg, C Emanuel, LC Powell, ... PLoS One 9 (11), e112518, 2014 | 83 | 2014 |
| A low-molecular-weight alginate oligosaccharide disrupts pseudomonal microcolony formation and enhances antibiotic effectiveness MF Pritchard, LC Powell, AA Jack, K Powell, K Beck, H Florance, J Forton, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00762-17, 2017 | 80 | 2017 |
| A Nanoscale Characterization of the Interaction of a Novel Alginate Oligomer with the Cell Surface and Motility of Pseudomonas aeruginosa LC Powell, MF Pritchard, C Emanuel, E Onsøyen, PD Rye, CJ Wright, ... American journal of respiratory cell and molecular biology 50 (3), 483-492, 2014 | 69 | 2014 |
| Alginate Oligosaccharide-Induced Modification of the lasI-lasR and rhlI-rhlR Quorum-Sensing Systems in Pseudomonas aeruginosa AA Jack, S Khan, LC Powell, MF Pritchard, K Beck, H Sadh, L Sutton, ... Antimicrobial Agents and Chemotherapy 62 (5), 10.1128/aac. 02318-17, 2018 | 54 | 2018 |
| Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones QE Yang, C MacLean, A Papkou, M Pritchard, L Powell, D Thomas, ... The ISME Journal 14 (3), 861-865, 2020 | 44 | 2020 |
| An in vitro study of alginate oligomer therapies on oral biofilms JL Roberts, S Khan, C Emanuel, LC Powell, MF Pritchard, E Onsøyen, ... Journal of dentistry 41 (10), 892-899, 2013 | 44 | 2013 |
| The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses Z Saud, VJ Tyrrell, A Zaragkoulias, MB Protty, E Statkute, A Rubina, ... Journal of Lipid Research 63 (6), 2022 | 34 | 2022 |
| Alginate oligosaccharides modify hyphal infiltration of Candida albicans in an in vitro model of invasive human candidosis MF Pritchard, AA Jack, LC Powell, H Sadh, PD Rye, KE Hill, DW Thomas Journal of Applied Microbiology 123 (3), 625-636, 2017 | 32 | 2017 |
| The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption MF Pritchard, LC Powell, S Khan, PC Griffiths, OT Mansour, R Schweins, ... Scientific reports 7 (1), 44731, 2017 | 26 | 2017 |
| Anti-pseudomonad Activity of Manuka Honey and Antibiotics in a Specialized ex vivo Model Simulating Cystic Fibrosis Lung Infection AEL Roberts, LC Powell, MF Pritchard, DW Thomas, RE Jenkins Frontiers in microbiology 10, 869, 2019 | 25 | 2019 |
| Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms. Nat Commun 8: 2054 Q Yang, M Li, OB Spiller, DO Andrey, P Hinchliffe, H Li, C MacLean, ... | 17 | 2017 |
| Mucin structural interactions with an alginate oligomer mucolytic in cystic fibrosis sputum MF Pritchard, JL Oakley, CD Brilliant, PD Rye, J Forton, IJM Doull, ... Vibrational Spectroscopy 103, 102932, 2019 | 16 | 2019 |
| Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides. NPJ Biofilms Microbiomes. 2018; 4: 13 LC Powell, MF Pritchard, EL Ferguson, KA Powell, SU Patel, PD Rye, ... DOI: https://doi. org/10.1038/s41522-018-0056-3, 0 | 12 | |
| Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds LC Powell, JK Cullen, GM Boyle, T De Ridder, PY Yap, W Xue, CJ Pierce, ... Science translational medicine 14 (662), eabn3758, 2022 | 11 | 2022 |
| Phenotypic and genotypic adaptations in Pseudomonas aeruginosa biofilms following long-term exposure to an alginate oligomer therapy JL Oakley, R Weiser, LC Powell, J Forton, E Mahenthiralingam, PD Rye, ... Msphere 6 (1), 10.1128/msphere. 01216-20, 2021 | 9 | 2021 |
| Surgical therapy for peri‐implantitis management: a systematic review and meta‐analysis KAH Al‐Kadhim, MF Pritchard, DJJ Farnell, DW Thomas, R Adams, ... Oral Surgery 11 (3), 200-212, 2018 | 9 | 2018 |
