Prof. Emmanuel A Asante
Prof. Emmanuel A Asante
Honorary Associate Professor Emeritus, UCL Institute of Prion Diseases, MRC Prion Unit at UCL
Verified email at - Homepage
Cited by
Cited by
Post‐natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration
GR Mallucci, S Ratte, EA Asante, J Linehan, I Gowland, JGR Jefferys, ...
The EMBO journal, 2002
BSE prions propagate as either variant CJD‐like or sporadic CJD‐like prion strains in transgenic mice expressing human prion protein
EA Asante, JM Linehan, M Desbruslais, S Joiner, I Gowland, AL Wood, ...
The EMBO journal, 2002
Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites
DB Freir, AJ Nicoll, I Klyubin, S Panico, JM Mc Donald, E Risse, ...
Nature communications 2 (1), 336, 2011
Human prion protein with valine 129 prevents expression of variant CJD phenotype
JDF Wadsworth, EA Asante, M Desbruslais, JM Linehan, S Joiner, ...
Science 306 (5702), 1793-1796, 2004
Unaltered susceptibility to BSE in transgenic mice expressing human prion protein
J Collinge, MS Palmer, KCL Sidle, AF Hill, I Gowland, J Meads, E Asante, ...
Nature 378 (6559), 779-783, 1995
Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy
DJ Wells, KE Wells, EA Asante, G Turner, Y Sunada, KP Campbell, ...
Human molecular genetics 4 (8), 1245-1250, 1995
A naturally occurring variant of the human prion protein completely prevents prion disease
EA Asante, M Smidak, A Grimshaw, R Houghton, A Tomlinson, A Jeelani, ...
Nature 522 (7557), 478, 2015
Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein
MK Sandberg, H Al-Doujaily, CJ Sigurdson, M Glatzel, C O'Malley, ...
Journal of General Virology 91 (10), 2651-2657, 2010
Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein
JDF Wadsworth, S Joiner, JM Linehan, S Cooper, C Powell, G Mallinson, ...
Brain 129 (6), 1557-1569, 2006
Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice
S Ghazi-Noori, KE Froud, S Mizielinska, C Powell, M Smidak, ...
Brain 135 (3), 819-832, 2012
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology
EL Clayton, S Mizielinska, JR Edgar, TT Nielsen, S Marshall, FE Norona, ...
Acta neuropathologica 130, 511-523, 2015
Kuru prions and sporadic Creutzfeldt–Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice
JDF Wadsworth, S Joiner, JM Linehan, M Desbruslais, K Fox, S Cooper, ...
Proceedings of the National Academy of Sciences 105 (10), 3885-3890, 2008
Dissociation of pathological and molecular phenotype of variant Creutzfeldt–Jakob disease in transgenic human prion protein 129 heterozygous mice
EA Asante, JM Linehan, I Gowland, S Joiner, K Fox, S Cooper, O Osiguwa, ...
Proceedings of the National Academy of Sciences 103 (28), 10759-10764, 2006
Isolation and functional characterisation of the promoter region of the human prion protein gene
SP Mahal, EA Asante, M Antoniou, J Collinge
Gene 268 (1-2), 105-114, 2001
Contribution of transgenic models to understanding human prion disease
JDF Wadsworth, EA Asante, J Collinge
Neuropathology and applied neurobiology 36 (7), 576-597, 2010
Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins
EA Asante, I Gowland, A Grimshaw, JM Linehan, M Smidak, R Houghton, ...
Journal of general virology 90 (3), 546-558, 2009
Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein
EA Asante, JM Linehan, M Smidak, A Tomlinson, A Grimshaw, A Jeelani, ...
PLoS pathogens 9 (9), e1003643, 2013
The origin of the prion agent of kuru: molecular and biological strain typing
JDF Wadsworth, S Joiner, JM Linehan, EA Asante, S Brandner, J Collinge
Philosophical Transactions of the Royal Society B: Biological Sciences 363 …, 2008
Enhancing health care system in Ghana through the integration of traditional medicines
E Asante, R Avornyo
Journal of Social Research 4 (2), 2013
Prion infectivity in variant Creutzfeldt–Jakob disease rectum
JDF Wadsworth, S Joiner, K Fox, JM Linehan, M Desbruslais, S Brandner, ...
Gut 56 (1), 90-94, 2007
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