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Prof. Emmanuel A Asante
Prof. Emmanuel A Asante
Honorary Associate Professor Emeritus, UCL Institute of Prion Diseases, MRC Prion Unit at UCL
Verified email at ucl.ac.uk - Homepage
Title
Cited by
Cited by
Year
Post‐natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration
GR Mallucci, S Ratte, EA Asante, J Linehan, I Gowland, JGR Jefferys, ...
The EMBO journal, 2002
5052002
BSE prions propagate as either variant CJD‐like or sporadic CJD‐like prion strains in transgenic mice expressing human prion protein
EA Asante, JM Linehan, M Desbruslais, S Joiner, I Gowland, AL Wood, ...
The EMBO journal, 2002
4522002
Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites
DB Freir, AJ Nicoll, I Klyubin, S Panico, JM Mc Donald, E Risse, ...
Nature communications 2 (1), 336, 2011
3432011
Human prion protein with valine 129 prevents expression of variant CJD phenotype
JDF Wadsworth, EA Asante, M Desbruslais, JM Linehan, S Joiner, ...
Science 306 (5702), 1793-1796, 2004
3162004
Unaltered susceptibility to BSE in transgenic mice expressing human prion protein
J Collinge, MS Palmer, KCL Sidle, AF Hill, I Gowland, J Meads, E Asante, ...
Nature 378 (6559), 779-783, 1995
2901995
Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy
DJ Wells, KE Wells, EA Asante, G Turner, Y Sunada, KP Campbell, ...
Human molecular genetics 4 (8), 1245-1250, 1995
2081995
A naturally occurring variant of the human prion protein completely prevents prion disease
EA Asante, M Smidak, A Grimshaw, R Houghton, A Tomlinson, A Jeelani, ...
Nature 522 (7557), 478, 2015
1992015
Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein
MK Sandberg, H Al-Doujaily, CJ Sigurdson, M Glatzel, C O'Malley, ...
Journal of General Virology 91 (10), 2651-2657, 2010
1692010
Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein
JDF Wadsworth, S Joiner, JM Linehan, S Cooper, C Powell, G Mallinson, ...
Brain 129 (6), 1557-1569, 2006
1132006
Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice
S Ghazi-Noori, KE Froud, S Mizielinska, C Powell, M Smidak, ...
Brain 135 (3), 819-832, 2012
1092012
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology
EL Clayton, S Mizielinska, JR Edgar, TT Nielsen, S Marshall, FE Norona, ...
Acta neuropathologica 130, 511-523, 2015
982015
Kuru prions and sporadic Creutzfeldt–Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice
JDF Wadsworth, S Joiner, JM Linehan, M Desbruslais, K Fox, S Cooper, ...
Proceedings of the National Academy of Sciences 105 (10), 3885-3890, 2008
872008
Dissociation of pathological and molecular phenotype of variant Creutzfeldt–Jakob disease in transgenic human prion protein 129 heterozygous mice
EA Asante, JM Linehan, I Gowland, S Joiner, K Fox, S Cooper, O Osiguwa, ...
Proceedings of the National Academy of Sciences 103 (28), 10759-10764, 2006
832006
Isolation and functional characterisation of the promoter region of the human prion protein gene
SP Mahal, EA Asante, M Antoniou, J Collinge
Gene 268 (1-2), 105-114, 2001
832001
Contribution of transgenic models to understanding human prion disease
JDF Wadsworth, EA Asante, J Collinge
Neuropathology and applied neurobiology 36 (7), 576-597, 2010
802010
Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins
EA Asante, I Gowland, A Grimshaw, JM Linehan, M Smidak, R Houghton, ...
Journal of general virology 90 (3), 546-558, 2009
762009
Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein
EA Asante, JM Linehan, M Smidak, A Tomlinson, A Grimshaw, A Jeelani, ...
PLoS pathogens 9 (9), e1003643, 2013
612013
The origin of the prion agent of kuru: molecular and biological strain typing
JDF Wadsworth, S Joiner, JM Linehan, EA Asante, S Brandner, J Collinge
Philosophical Transactions of the Royal Society B: Biological Sciences 363 …, 2008
592008
Enhancing health care system in Ghana through the integration of traditional medicines
E Asante, R Avornyo
Journal of Social Research 4 (2), 2013
422013
Prion infectivity in variant Creutzfeldt–Jakob disease rectum
JDF Wadsworth, S Joiner, K Fox, JM Linehan, M Desbruslais, S Brandner, ...
Gut 56 (1), 90-94, 2007
412007
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