| Post‐natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration GR Mallucci, S Ratte, EA Asante, J Linehan, I Gowland, JGR Jefferys, ... The EMBO journal, 2002 | 507 | 2002 |
| BSE prions propagate as either variant CJD‐like or sporadic CJD‐like prion strains in transgenic mice expressing human prion protein EA Asante, JM Linehan, M Desbruslais, S Joiner, I Gowland, AL Wood, ... The EMBO journal, 2002 | 457 | 2002 |
| Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites DB Freir, AJ Nicoll, I Klyubin, S Panico, JM Mc Donald, E Risse, ... Nature communications 2 (1), 336, 2011 | 350 | 2011 |
| Human prion protein with valine 129 prevents expression of variant CJD phenotype JDF Wadsworth, EA Asante, M Desbruslais, JM Linehan, S Joiner, ... Science 306 (5702), 1793-1796, 2004 | 319 | 2004 |
| Unaltered susceptibility to BSE in transgenic mice expressing human prion protein J Collinge, MS Palmer, KCL Sidle, AF Hill, I Gowland, J Meads, E Asante, ... Nature 378 (6559), 779-783, 1995 | 290 | 1995 |
| Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy DJ Wells, KE Wells, EA Asante, G Turner, Y Sunada, KP Campbell, ... Human molecular genetics 4 (8), 1245-1250, 1995 | 210 | 1995 |
| A naturally occurring variant of the human prion protein completely prevents prion disease EA Asante, M Smidak, A Grimshaw, R Houghton, A Tomlinson, A Jeelani, ... Nature 522 (7557), 478, 2015 | 205 | 2015 |
| Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein MK Sandberg, H Al-Doujaily, CJ Sigurdson, M Glatzel, C O'Malley, ... Journal of General Virology 91 (10), 2651-2657, 2010 | 171 | 2010 |
| Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein JDF Wadsworth, S Joiner, JM Linehan, S Cooper, C Powell, G Mallinson, ... Brain 129 (6), 1557-1569, 2006 | 113 | 2006 |
| Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice S Ghazi-Noori, KE Froud, S Mizielinska, C Powell, M Smidak, ... Brain 135 (3), 819-832, 2012 | 112 | 2012 |
| Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology EL Clayton, S Mizielinska, JR Edgar, TT Nielsen, S Marshall, FE Norona, ... Acta neuropathologica 130, 511-523, 2015 | 99 | 2015 |
| Kuru prions and sporadic Creutzfeldt–Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice JDF Wadsworth, S Joiner, JM Linehan, M Desbruslais, K Fox, S Cooper, ... Proceedings of the National Academy of Sciences 105 (10), 3885-3890, 2008 | 88 | 2008 |
| Dissociation of pathological and molecular phenotype of variant Creutzfeldt–Jakob disease in transgenic human prion protein 129 heterozygous mice EA Asante, JM Linehan, I Gowland, S Joiner, K Fox, S Cooper, O Osiguwa, ... Proceedings of the National Academy of Sciences 103 (28), 10759-10764, 2006 | 84 | 2006 |
| Isolation and functional characterisation of the promoter region of the human prion protein gene SP Mahal, EA Asante, M Antoniou, J Collinge Gene 268 (1-2), 105-114, 2001 | 83 | 2001 |
| Contribution of transgenic models to understanding human prion disease JDF Wadsworth, EA Asante, J Collinge Neuropathology and applied neurobiology 36 (7), 576-597, 2010 | 81 | 2010 |
| Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins EA Asante, I Gowland, A Grimshaw, JM Linehan, M Smidak, R Houghton, ... Journal of general virology 90 (3), 546-558, 2009 | 78 | 2009 |
| Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein EA Asante, JM Linehan, M Smidak, A Tomlinson, A Grimshaw, A Jeelani, ... PLoS pathogens 9 (9), e1003643, 2013 | 62 | 2013 |
| The origin of the prion agent of kuru: molecular and biological strain typing JDF Wadsworth, S Joiner, JM Linehan, EA Asante, S Brandner, J Collinge Philosophical Transactions of the Royal Society B: Biological Sciences 363 …, 2008 | 60 | 2008 |
| Enhancing health care system in Ghana through the integration of traditional medicines E Asante, R Avornyo Journal of Social Research 4 (2), 2013 | 44 | 2013 |
| Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein JDF Wadsworth, S Joiner, JM Linehan, A Balkema-Buschmann, ... Emerging infectious diseases 19 (11), 1731, 2013 | 41 | 2013 |
