Regina Cencic
Regina Cencic
Verified email at mcgill.ca
Title
Cited by
Cited by
Year
Antitumor activity and mechanism of action of the cyclopenta [b] benzofuran, silvestrol
R Cencic, M Carrier, G Galicia-Vázquez, ME Bordeleau, R Sukarieh, ...
PloS one 4 (4), e5223, 2009
2432009
Structural conservation of druggable hot spots in protein–protein interfaces
D Kozakov, DR Hall, GY Chuang, R Cencic, R Brenke, LE Grove, ...
Proceedings of the National Academy of Sciences 108 (33), 13528-13533, 2011
2152011
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F
R Cencic, DR Hall, F Robert, Y Du, J Min, L Li, M Qui, I Lewis, S Kurtkaya, ...
Proceedings of the National Academy of Sciences 108 (3), 1046-1051, 2011
1402011
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F
R Cencic, DR Hall, F Robert, Y Du, J Min, L Li, M Qui, I Lewis, S Kurtkaya, ...
Proceedings of the National Academy of Sciences 108 (3), 1046-1051, 2011
1382011
RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation
ME Bordeleau, R Cencic, L Lindqvist, M Oberer, P Northcote, G Wagner, ...
Chemistry & biology 13 (12), 1287-1295, 2006
1382006
c-Myc and eIF4F are components of a feedforward loop that links transcription and translation
CJ Lin, R Cencic, JR Mills, F Robert, J Pelletier
Cancer research 68 (13), 5326-5334, 2008
1362008
Repurposing CRISPR/Cas9 for in situ functional assays
A Malina, JR Mills, R Cencic, Y Yan, J Fraser, LM Schippers, M Paquet, ...
Genes & development 27 (23), 2602-2614, 2013
1222013
Enantioselective Synthesis of the Complex Rocaglate (−)‐Silvestrol
B Gerard, R Cencic, J Pelletier, JA Porco Jr
Angewandte Chemie 119 (41), 7977-7980, 2007
1072007
Selective pharmacological targeting of a DEAD box RNA helicase
L Lindqvist, M Oberer, M Reibarkh, R Cencic, ME Bordeleau, E Vogt, ...
PloS one 3 (2), e1583, 2008
1042008
Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage
R Cencic, H Miura, A Malina, F Robert, S Ethier, TM Schmeing, J Dostie, ...
PloS one 9 (10), e109213, 2014
922014
A cellular response linking eIF4AI activity to eIF4AII transcription
G Galicia-Vázquez, R Cencic, F Robert, AQ Agenor, J Pelletier
Rna 18 (7), 1373-1384, 2012
772012
Targeting translation dependence in cancer
A Malina, R Cencic, J Pelletier
Oncotarget 2 (1-2), 76, 2011
652011
Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication
R Cencic, M Desforges, DR Hall, D Kozakov, Y Du, J Min, R Dingledine, ...
Journal of virology 85 (13), 6381-6389, 2011
622011
Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells
R Cencic, M Carrier, A Trnkus, JA Porco Jr, M Minden, J Pelletier
Leukemia research 34 (4), 535-541, 2010
622010
Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies
CM Rodrigo, R Cencic, SP Roche, J Pelletier, JA Porco Jr
Journal of medicinal chemistry 55 (1), 558-562, 2012
572012
Biomimetic Photocycloaddition of 3‐Hydroxyflavones: Synthesis and Evaluation of Rocaglate Derivatives as Inhibitors of Eukaryotic Translation
SP Roche, R Cencic, J Pelletier, JA Porco Jr
Angewandte Chemie 122 (37), 6683-6688, 2010
532010
Foot-and-Mouth Disease Virus Leader Proteinase INVOLVEMENT OF C-TERMINAL RESIDUES IN SELF-PROCESSING AND CLEAVAGE OF eIF4GI
W Glaser, R Cencic, T Skern
Journal of Biological Chemistry 276 (38), 35473-35481, 2001
482001
Foot-and-Mouth Disease Virus Leader Proteinase INVOLVEMENT OF C-TERMINAL RESIDUES IN SELF-PROCESSING AND CLEAVAGE OF eIF4GI
W Glaser, R Cencic, T Skern
Journal of Biological Chemistry 276 (38), 35473-35481, 2001
482001
Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A
R Cencic, F Robert, G Galicia-Vazquez, A Malina, K Ravindar, R Somaiah, ...
Blood cancer journal 3 (7), e128-e128, 2013
432013
CRISPR-mediated drug-target validation reveals selective pharmacological inhibition of the RNA helicase, eIF4A
J Chu, G Galicia-Vázquez, R Cencic, JR Mills, A Katigbak, JA Porco Jr, ...
Cell reports 15 (11), 2340-2347, 2016
412016
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