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Hazem E. Ghoneim
Hazem E. Ghoneim
Assistant Professor, College of Medicine, The Ohio State University
Verified email at osumc.edu - Homepage
Title
Cited by
Cited by
Year
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
F Alfei, K Kanev, M Hofmann, M Wu, HE Ghoneim, P Roelli, ...
Nature 571 (7764), 265-269, 2019
6812019
De novo epigenetic programs inhibit PD-1 blockade-mediated T cell rejuvenation
HE Ghoneim, Y Fan, A Moustaki, HA Abdelsamed, P Dash, P Dogra, ...
Cell 170 (1), 142-157. e19, 2017
6372017
Effector CD8 T cells dedifferentiate into long-lived memory cells
B Youngblood, JS Hale, HT Kissick, E Ahn, X Xu, A Wieland, K Araki, ...
Nature 552 (7685), 404-409, 2017
4602017
Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections
HE Ghoneim, PG Thomas, JA McCullers
The Journal of Immunology 191 (3), 1250-1259, 2013
4142013
Developmental plasticity allows outside-in immune responses by resident memory T cells
R Fonseca, LK Beura, CF Quarnstrom, HE Ghoneim, Y Fan, CC Zebley, ...
Nature immunology 21 (4), 412-421, 2020
2372020
Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis
HA Abdelsamed, A Moustaki, Y Fan, P Dogra, HE Ghoneim, CC Zebley, ...
Journal of Experimental Medicine 214 (6), 1593-1606, 2017
1392017
Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59
AH Ellebedy, C Lupfer, HE Ghoneim, J DeBeauchamp, TD Kanneganti, ...
Proceedings of the National Academy of Sciences 108 (7), 2927-2932, 2011
1282011
Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden, in pregnant mice
G Marcelin, JR Aldridge, S Duan, HE Ghoneim, J Rehg, H Marjuki, ...
Journal of virology 85 (21), 11208-11219, 2011
962011
Immunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82
IV Alymova, AM Green, N van de Velde, JL McAuley, KL Boyd, ...
Journal of virology 85 (23), 12324-12333, 2011
922011
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
HA Abdelsamed, CC Zebley, H Nguyen, RL Rutishauser, Y Fan, ...
Nature immunology 21 (5), 578-587, 2020
742020
Functional T cells are capable of supernumerary cell division and longevity
AG Soerens, M Künzli, CF Quarnstrom, MC Scott, L Swanson, ...
Nature 614 (7949), 762-766, 2023
702023
Cell-intrinsic barriers of T cell-based immunotherapy
HE Ghoneim, AE Zamora, PG Thomas, BA Youngblood
Trends in molecular medicine 22 (12), 1000-1011, 2016
692016
Adjunctive corticosteroid therapy improves lung immunopathology and survival during severe secondary pneumococcal pneumonia in mice
HE Ghoneim, JA McCullers
The Journal of infectious diseases 209 (9), 1459-1468, 2014
582014
Generating long‐lived CD8+ T‐cell memory: Insights from epigenetic programs
P Dogra, HE Ghoneim, HA Abdelsamed, B Youngblood
European journal of immunology 46 (7), 1548-1562, 2016
342016
Influenza A virus directly modulates mouse eosinophil responses
KS LeMessurier, R Rooney, HE Ghoneim, B Liu, K Li, HS Smallwood, ...
Journal of Leucocyte Biology 108 (1), 151-168, 2020
302020
Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation
CC Zebley, HA Abdelsamed, HE Ghoneim, S Alli, C Brown, D Haydar, ...
Cell reports 37 (2), 2021
172021
Rebalancing TGFβ1/BMP signals in exhausted T cells unlocks responsiveness to immune checkpoint blockade therapy
AA Saadey, A Yousif, N Osborne, R Shahinfar, YL Chen, B Laster, ...
Nature immunology 24 (2), 280-294, 2023
112023
Epigenetic remodeling by vitamin C potentiates plasma cell differentiation
HY Chen, A Almonte-Loya, FY Lay, M Hsu, E Johnson, ...
Elife 11, e73754, 2022
102022
Gene regulatory circuits in innate and adaptive immune cells
A Saini, HE Ghoneim, CWJ Lio, PL Collins, EM Oltz
Annual review of immunology 40, 387-411, 2022
92022
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity
KA Read, DM Jones, S Pokhrel, EDS Hales, A Varkey, JA Tuazon, ...
Nature Communications 14 (1), 1652, 2023
82023
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