| Binding of a novel SMG-1–Upf1–eRF1–eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay I Kashima, A Yamashita, N Izumi, N Kataoka, R Morishita, S Hoshino, ... Genes & development 20 (3), 355-367, 2006 | 709 | 2006 |
| Concerted action of poly (A) nucleases and decapping enzyme in mammalian mRNA turnover A Yamashita, TC Chang, Y Yamashita, W Zhu, Z Zhong, CYA Chen, ... Nature structural & molecular biology 12 (12), 1054-1063, 2005 | 668 | 2005 |
| Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of … A Yamashita, T Ohnishi, I Kashima, Y Taya, S Ohno Genes & development 15 (17), 2215-2228, 2001 | 485 | 2001 |
| Nonsense-mediated mRNA decay—mechanisms of substrate mRNA recognition and degradation in mammalian cells C Schweingruber, SC Rufener, D Zünd, A Yamashita, O Mühlemann Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (6-7 …, 2013 | 385 | 2013 |
| Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7 T Ohnishi, A Yamashita, I Kashima, T Schell, KR Anders, A Grimson, ... Molecular cell 12 (5), 1187-1200, 2003 | 382 | 2003 |
| PAR‐6 regulates aPKC activity in a novel way and mediates cell‐cell contact‐induced formation of the epithelial junctional complex T Yamanaka, Y Horikoshi, A Suzuki, Y Sugiyama, K Kitamura, R Maniwa, ... Genes to Cells 6 (8), 721-731, 2001 | 367 | 2001 |
| SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay A Yamashita, N Izumi, I Kashima, T Ohnishi, B Saari, Y Katsuhata, ... Genes & development 23 (9), 1091-1105, 2009 | 279 | 2009 |
| N-and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5: SMG-7 during NMD Y Okada-Katsuhata, A Yamashita, K Kutsuzawa, N Izumi, F Hirahara, ... Nucleic acids research 40 (3), 1251-1266, 2012 | 249 | 2012 |
| Human TOB, an antiproliferative transcription factor, is a poly (A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation N Ezzeddine, TC Chang, W Zhu, A Yamashita, CYA Chen, Z Zhong, ... Molecular and cellular biology 27 (22), 7791-7801, 2007 | 192 | 2007 |
| Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy H Saitsu, H Osaka, M Sasaki, J Takanashi, K Hamada, A Yamashita, ... The American Journal of Human Genetics 89 (5), 644-651, 2011 | 183 | 2011 |
| UNR, a new partner of poly (A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant TC Chang, A Yamashita, CYA Chen, Y Yamashita, W Zhu, S Durdan, ... Genes & development 18 (16), 2010-2023, 2004 | 178 | 2004 |
| AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay N Izumi, A Yamashita, A Iwamatsu, R Kurata, H Nakamura, B Saari, ... Science signaling 3 (116), ra27-ra27, 2010 | 161 | 2010 |
| An atlas of substrate specificities for the human serine/threonine kinome JL Johnson, TM Yaron, EM Huntsman, A Kerelsky, J Song, A Regev, ... Nature 613 (7945), 759-766, 2023 | 160 | 2023 |
| Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor M Baba, S Hirai, H Yamada-Okabe, K Hamada, H Tabuchi, K Kobayashi, ... Oncogene 22 (18), 2728-2738, 2003 | 127 | 2003 |
| Inhibition of nonsense‐mediated mRNA decay rescues the phenotype in Ullrich's disease F Usuki, A Yamashita, I Higuchi, T Ohnishi, T Shiraishi, M Osame, S Ohno Annals of Neurology: Official Journal of the American Neurological …, 2004 | 104 | 2004 |
| Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich disease fibroblasts F Usuki, A Yamashita, I Kashima, I Higuchi, M Osame, S Ohno Molecular Therapy 14 (3), 351-360, 2006 | 103 | 2006 |
| The role of SMG-1 in nonsense-mediated mRNA decay A Yamashita, I Kashima, S Ohno Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1754 (1-2), 305-315, 2005 | 99 | 2005 |
| Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD R Melero, A Uchiyama, R Castaño, N Kataoka, H Kurosawa, S Ohno, ... Structure 22 (8), 1105-1119, 2014 | 98 | 2014 |
| New vaccine production platforms used in developing SARS-CoV-2 vaccine candidates T Ura, A Yamashita, N Mizuki, K Okuda, M Shimada Vaccine 39 (2), 197-201, 2021 | 97 | 2021 |
| The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8 E Arias-Palomo, A Yamashita, IS Fernández, R Núñez-Ramírez, Y Bamba, ... Genes & development 25 (2), 153-164, 2011 | 91 | 2011 |
Shigeo OhnoProfessor of Molecular Biology, Yokohama City University School of MedicineVerified email at med.yokohama-cu.ac.jp
