Sulfonate/Nitro Bearing Methylmalonyl-Thioester Isosteres Applied to Methylmalonyl-CoA Decarboxylase Structure–Function Studies LM Stunkard, AD Dixon, TJ Huth, JR Lohman Journal of the American Chemical Society 141 (13), 5121-5124, 2019 | 20 | 2019 |
Structures of LnmK, a bifunctional acyltransferase/decarboxylase, with substrate analogues reveal the basis for selectivity and stereospecificity LM Stunkard, BJ Kick, JR Lohman Biochemistry 60 (5), 365-372, 2021 | 8 | 2021 |
Activity of fatty acid biosynthesis initiating ketosynthase FabH with acetyl/malonyl-oxa/aza (dethia) CoAs TJ Boram, AB Benjamin, A Silva de Sousa, LM Stunkard, TA Stewart, ... ACS chemical biology 18 (1), 49-58, 2023 | 4 | 2023 |
Substrate Enolate Intermediate and Mimic Captured in the Active Site of Streptomyces coelicolor Methylmalonyl‐CoA Epimerase** LM Stunkard, AB Benjamin, JB Bower, TJ Huth, JR Lohman ChemBioChem 23 (2), e202100487, 2022 | 2 | 2022 |
Exploring Enzymatic β‐Keto Acid (De) Carboxylation with Malonyl‐CoA Analogs J Lohman, L Stunkard, A Benjamin, T Boram The FASEB Journal 33 (S1), 633.17-633.17, 2019 | 2 | 2019 |
Structure-Based Prototyping of Allosteric Inhibitors of Human Uridine/Cytidine Kinase 2 (UCK2) S Mashayekh, LM Stunkard, M Kienle, II Mathews, C Khosla Biochemistry 61 (21), 2261-2266, 2022 | 1 | 2022 |
Structures of chloramphenicol acetyltransferase III and Escherichia coli β-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa (dethia) CoA AB Benjamin, LM Stunkard, J Ling, JN Nice, JR Lohman Acta Crystallographica Section F: Structural Biology Communications 79 (3 …, 2023 | | 2023 |
Structures of chloramphenicol acetyltransferase III and E. coli β-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(dethia)CoA AB Benjamin, LM Stunkard, J Ling, JN Nice, JR Lohman bioRxiv, 2022.08. 24.505111, 2022 | | 2022 |
Malonyl-coenzyme A mimics as fatty acid synthase inhibitors and methods of use JR Lohman, LM Stunkard US Patent 11,008,362, 2021 | | 2021 |
Crystal Structures of Streptomyces Coelicolor Methylmalonyl-CoA Epimerase with Substrate or Transition State Analog Contradicts a Simple General Acid-Base Catalytic Mechanism LM Stunkard, AB Benjamin, J Bower, T Huth, J Lohman | | 2021 |
Unveiling Enzymatic Mechanisms with Malonyl-Thioester Isosteres L Stunkard Purdue University, 2019 | | 2019 |
Elucidating the Molecular Details of Catalysis for Type III Polyketide Synthases Using Near Natural Substrate/Intermediate Analogs LR Richards, L Stunkard, A Benjamin, BP Manning, J Lohman The FASEB Journal 31, lb110-lb110, 2017 | | 2017 |
Investigating the Catalytic Molecular Details of Malonyl‐thioester Decarboxylating Enzymes LM Stunkard, JM Lohman The FASEB Journal 31, lb96-lb96, 2017 | | 2017 |
Expression and Site-Directed Mutagenesis of Type III Polyketide Synthases LR Richards, O Goudy, LM Stunkard, AB Benjamin, BP Manning, ... | | 2016 |
Biochemical and structural characterization of Cdc14 phosphatases from pathogenic fungi J Whitney, K Wettschurack, M Hall, J Lohman, A Benjamin, LM Stunkard | | 2016 |