Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus JL Trejo, E Carro, I Torres-Aleman Journal of Neuroscience 21 (5), 1628-1634, 2001 | 1362 | 2001 |
Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy E Carro, JL Trejo, S Busiguina, I Torres-Aleman Journal of Neuroscience 21 (15), 5678-5684, 2001 | 931 | 2001 |
Serum insulin-like growth factor I regulates brain amyloid-β levels E Carro, JL Trejo, T Gomez-Isla, D LeRoith, I Torres-Aleman Nature medicine 8 (12), 1390-1397, 2002 | 705 | 2002 |
The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis JL Trejo, MV Llorens-Martin, I Torres-Alemán Molecular and Cellular Neuroscience 37 (2), 402-411, 2008 | 374 | 2008 |
Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I E Carro, C Spuch, JL Trejo, D Antequera, I Torres-Aleman Journal of Neuroscience 25 (47), 10884-10893, 2005 | 259 | 2005 |
Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects JL Trejo, J Piriz, MV Llorens-Martin, AM Fernandez, M Bolos, D LeRoith, ... Molecular psychiatry 12 (12), 1118-1128, 2007 | 251 | 2007 |
In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases JI Diaz-Hernandez, R Gomez-Villafuertes, M León-Otegui, ... Neurobiology of aging 33 (8), 1816-1828, 2012 | 217 | 2012 |
Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis E Carro, JL Trejo, A Gerber, H Loetscher, J Torrado, F Metzger, ... Neurobiology of aging 27 (9), 1250-1257, 2006 | 197 | 2006 |
Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation S Pons, J Luis Trejo, J Ramón Martínez-Morales, E Martí Development 128 (9), 1481-1492, 2001 | 197 | 2001 |
Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome C Martínez-Cué, P Martínez, N Rueda, R Vidal, S García, V Vidal, ... Journal of Neuroscience 33 (9), 3953-3966, 2013 | 195 | 2013 |
Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal V Hernández-Rabaza, M Llorens-Martín, C Velázquez-Sánchez, ... Neuroscience 159 (1), 59-68, 2009 | 186 | 2009 |
Reviews: mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis M LLorens-Martin, I Torres-Aleman, JL Trejo The neuroscientist 15 (2), 134-148, 2009 | 173 | 2009 |
Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease? E Carro, JL Trejo, C Spuch, D Bohl, JM Heard, I Torres-Aleman Neurobiology of aging 27 (11), 1618-1631, 2006 | 171 | 2006 |
An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin‐like growth factor‐I in the dentate gyrus of adult female rat M Perez‐Martin, I Azcoitia, JL Trejo, A Sierra, LM Garcia‐Segura European Journal of Neuroscience 18 (4), 923-930, 2003 | 164 | 2003 |
Exercise modulates insulin-like growth factor 1-dependent and-independent effects on adult hippocampal neurogenesis and behaviour M LLorens-Martín, I Torres-Alemán, JL Trejo Molecular and Cellular Neuroscience 44 (2), 109-117, 2010 | 163 | 2010 |
Brain repair and neuroprotection by serum insulin-like growth factor I E Carro, JL Trejo, A Núñez, I Torres-Aleman Molecular neurobiology 27, 153-162, 2003 | 155 | 2003 |
Role of insulin-like growth factor I signaling in neurodegenerative diseases JL Trejo, E Carro, E Garcia-Galloway, I Torres-Aleman Journal of Molecular Medicine 82, 156-162, 2004 | 147 | 2004 |
The hippocampal dentate gyrus is essential for generating contextual memories of fear and drug-induced reward V Hernández-Rabaza, L Hontecillas-Prieto, C Velázquez-Sánchez, ... Neurobiology of learning and memory 90 (3), 553-559, 2008 | 131 | 2008 |
Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome N Rueda, M Llorens-Martín, J Flórez, E Valdizán, P Banerjee, JL Trejo, ... Journal of Alzheimer's Disease 21 (1), 277-290, 2010 | 125 | 2010 |
Pronounced individual variation in the response to the stimulatory action of exercise on immature hippocampal neurons M Llorens‐Martín, I Torres‐Alemán, JL Trejo Hippocampus 16 (5), 480-490, 2006 | 116 | 2006 |