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Amberley D Stephens
Amberley D Stephens
Verified email at astrazeneca.com
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Cited by
Cited by
Year
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
J Lautenschläger, AD Stephens, G Fusco, F Ströhl, N Curry, ...
Nature communications 9 (1), 712, 2018
2732018
Structural basis of synaptic vesicle assembly promoted by α-synuclein
G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, ...
Nature communications 7 (1), 12563, 2016
2422016
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ...
Nature communications 11 (1), 2820, 2020
1092020
The cellular environment affects monomeric α-synuclein structure
AD Stephens, M Zacharopoulou, GSK Schierle
Trends in biochemical sciences 44 (5), 453-466, 2019
712019
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans
C Huang, S Wagner-Valladolid, AD Stephens, R Jung, C Poudel, ...
Elife 8, e43059, 2019
572019
Different structural conformers of monomeric alpha-synuclein identified after lyophilising and freezing
AD Stephens, N Nespovitaya, M Zacharopoulou, CF Kaminski, JJ Phillips, ...
Analytical chemistry, 2018
392018
Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies
J Lautenschläger, S Wagner-Valladolid, AD Stephens, ...
Journal of Biological Chemistry 295 (30), 10138-10152, 2020
292020
The role of water in amyloid aggregation kinetics
AD Stephens, GSK Schierle
Current opinion in structural biology 58, 115-123, 2019
272019
Short hydrogen bonds enhance nonaromatic protein-related fluorescence
AD Stephens, MN Qaisrani, MT Ruggiero, G Díaz Mirón, UN Morzan, ...
Proceedings of the National Academy of Sciences 118 (21), e2020389118, 2021
252021
Observation of high-temperature macromolecular confinement in lyophilised protein formulations using terahertz spectroscopy
TA Shmool, PJ Woodhams, M Leutzsch, AD Stephens, MU Gaimann, ...
International journal of pharmaceutics: X 1, 100022, 2019
242019
Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements
RM Delahay, NJ Croxall, AD Stephens
Mobile DNA 9, 1-20, 2018
212018
Intracellular Aβ42 aggregation leads to cellular thermogenesis
CW Chung, AD Stephens, T Konno, E Ward, E Avezov, CF Kaminski, ...
Journal of the American Chemical Society 144 (22), 10034-10041, 2022
172022
Purification of recombinant α-Synuclein: a comparison of commonly used protocols
A Stephens, D Matak-Vinkovic, A Fernandez-Villegas, ...
Biochemistry 59 (48), 4563-4572, 2020
172020
Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins
KH Jong, YT Azar, L Grisanti, AD Stephens, STE Jones, D Credgington, ...
Physical Chemistry Chemical Physics 21 (43), 23931-23942, 2019
162019
Millisecond hydrogen/deuterium-exchange mass spectrometry approach to correlate local structure and aggregation in α-synuclein
N Seetaloo, M Zacharopoulou, AD Stephens, GS Kaminski Schierle, ...
Analytical Chemistry 94 (48), 16711-16719, 2022
112022
Decreased water mobility contributes to increased α‐synuclein aggregation
AD Stephens, J Kölbel, R Moons, CW Chung, MT Ruggiero, N Mahmoudi, ...
Angewandte Chemie International Edition 62 (7), e202212063, 2023
102023
Label-free characterisation of amyloids and alpha-Synuclein polymorphs by exploiting their intrinsic fluorescence property
CW Chung, AD Stephens, E Ward, Y Feng, MJ Davis, CF Kaminski, ...
Analytical Chemistry 94 (13), 5367–5374, 2022
102022
Fast Purification of Recombinant Monomeric Amyloid‑β from E. coli and Amyloid-β-mCherry Aggregates from Mammalian Cells
A Stephens, M Lu, A Fernandez-Villegas, G Kaminski Schierle
ACS Chemical Neuroscience 11, 3204-3213, 2020
82020
TE; Credgington, D.; Kaminski Schierle, GS; Hassanali, A. Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins
KH Jong, YT Azar, L Grisanti, AD Stephens, S Jones
Phys. Chem. Chem. Phys 21 (43), 23931-23942, 2019
62019
The role of water mobility in protein misfolding
AD Stephens, J Kölbel, R Moons, MT Ruggerio, N Mahmoudi, TA Shmool, ...
bioRxiv, 2021.01. 06.425575, 2021
52021
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Articles 1–20