Arthur Christopoulos
Arthur Christopoulos
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TitleCited byYear
Fitting models to biological data using linear and nonlinear regression: a practical guide to curve fitting
H Motulsky, A Christopoulos
Oxford University Press, 2004
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
PJ Conn, A Christopoulos, CW Lindsley
Nature reviews Drug discovery 8 (1), 41, 2009
G protein-coupled receptor allosterism and complexing
A Christopoulos, T Kenakin
Pharmacological reviews 54 (2), 323-374, 2002
International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acidB receptors: structure and function
NG Bowery, B Bettler, W Froestl, JP Gallagher, F Marshall, M Raiteri, ...
Pharmacological reviews 54 (2), 247-264, 2002
Allosteric binding sites on cell-surface receptors: novel targets for drug discovery
A Christopoulos
Nature reviews Drug discovery 1 (3), 198, 2002
Allosteric modulation of G protein–coupled receptors
LT May, K Leach, PM Sexton, A Christopoulos
Annu. Rev. Pharmacol. Toxicol. 47, 1-51, 2007
Activation and allosteric modulation of a muscarinic acetylcholine receptor
AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ...
Nature 504 (7478), 101, 2013
Signalling bias in new drug discovery: detection, quantification and therapeutic impact
T Kenakin, A Christopoulos
Nature reviews Drug discovery 12 (3), 205, 2013
International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology
RR Neubig, M Spedding, T Kenakin, A Christopoulos
Pharmacological reviews 55 (4), 597-606, 2003
The Concise Guide to PHARMACOLOGY 2017/18: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, NV Marrion, ...
British journal of pharmacology 174, S17-S129, 2017
G-protein–coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
E Kostenis, G Milligan, A Christopoulos, CF Sanchez-Ferrer, ...
Circulation 111 (14), 1806-1813, 2005
Inflammatory cytokines IL-1α, IL-1β, IL-6, and TNF-α impart neuroprotection to an excitotoxin through distinct pathways
NG Carlson, WA Wieggel, J Chen, A Bacchi, SW Rogers, LC Gahring
The Journal of Immunology 163 (7), 3963-3968, 1999
Allosteric modulation of the cannabinoid CB1 receptor
MR Price, GL Baillie, A Thomas, LA Stevenson, M Easson, R Goodwin, ...
Molecular pharmacology 68 (5), 1484-1495, 2005
Emerging paradigms in GPCR allostery: implications for drug discovery
D Wootten, A Christopoulos, PM Sexton
Nature reviews Drug discovery 12 (8), 630, 2013
Muscarinic Receptors (Handbook of Experimental Pharmacology)
NM Nathanson, A Christopoulos, AD Fryer
Springer Berlin Heidelberg, 2012
Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology
K Leach, PM Sexton, A Christopoulos
Trends in pharmacological sciences 28 (8), 382-389, 2007
Novel receptor partners and function of receptor activity-modifying proteins
A Christopoulos, G Christopoulos, M Morfis, M Udawela, M Laburthe, ...
Journal of Biological Chemistry 278 (5), 3293-3297, 2003
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs
RO Dror, HF Green, C Valant, DW Borhani, JR Valcourt, AC Pan, ...
Nature 503 (7475), 295, 2013
A simple method for quantifying functional selectivity and agonist bias
T Kenakin, C Watson, V Muniz-Medina, A Christopoulos, S Novick
ACS chemical neuroscience 3 (3), 193-203, 2012
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