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Robert J. Lee
Robert J. Lee
Assistant Professor, Department of Otorhinolaryngology, University of Pennsylvania
Verified email at pennmedicine.upenn.edu - Homepage
Title
Cited by
Cited by
Year
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
RJ Lee, G Xiong, JM Kofonow, B Chen, A Lysenko, P Jiang, V Abraham, ...
The Journal of clinical investigation 122 (11), 4145-4159, 2012
5572012
Bitter and sweet taste receptors regulate human upper respiratory innate immunity
RJ Lee, JM Kofonow, PL Rosen, AP Siebert, B Chen, L Doghramji, ...
The Journal of clinical investigation 124 (3), 1393-1405, 2014
4042014
Chronic rhinosinusitis pathogenesis
WW Stevens, RJ Lee, RP Schleimer, NA Cohen
Journal of Allergy and Clinical Immunology 136 (6), 1442-1453, 2015
3802015
The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery
ND Adappa, Z Zhang, JN Palmer, DW Kennedy, L Doghramji, A Lysenko, ...
International forum of allergy & rhinology 4 (1), 3-7, 2014
1702014
Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability
Z Ma, AP Siebert, KH Cheung, RJ Lee, B Johnson, AS Cohen, ...
Proceedings of the National Academy of Sciences 109 (28), E1963-E1971, 2012
1642012
CALHM3 is essential for rapid ion channel-mediated purinergic neurotransmission of GPCR-mediated tastes
Z Ma, A Taruno, M Ohmoto, M Jyotaki, JC Lim, H Miyazaki, N Niisato, ...
Neuron 98 (3), 547-561. e10, 2018
1542018
Taste receptors in innate immunity
RJ Lee, NA Cohen
Cellular and molecular life sciences 72, 217-236, 2015
1542015
Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein
RJ Lee, C Liu, C Harty, AA McCracken, M Latterich, K Römisch, ...
The EMBO journal 23 (11), 2206-2215, 2004
1492004
First contact: the role of respiratory cilia in host-pathogen interactions in the airways
LE Kuek, RJ Lee
American Journal of Physiology-Lung Cellular and Molecular Physiology 319 (4 …, 2020
1242020
Bitter and sweet taste receptors in the respiratory epithelium in health and disease
RJ Lee, NA Cohen
Journal of molecular medicine 92, 1235-1244, 2014
1172014
Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components
RJ Lee, B Chen, KM Redding, RF Margolskee, NA Cohen
Innate immunity 20 (6), 606-617, 2014
1082014
Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells
RJ Lee, BM Hariri, DB McMahon, B Chen, L Doghramji, ND Adappa, ...
Science signaling 10 (495), eaam7703, 2017
1042017
Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor
BM Hariri, DB McMahon, B Chen, JR Freund, CJ Mansfield, LJ Doghramji, ...
Journal of Biological Chemistry 292 (20), 8484-8497, 2017
1032017
Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention
ND Adappa, TJ Howland, JN Palmer, DW Kennedy, L Doghramji, ...
International Forum of Allergy & Rhinology, 2013
1022013
Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis
RJ Lee, NA Cohen
Current opinion in allergy and clinical immunology 15 (1), 14-20, 2015
952015
Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling
JR Freund, CJ Mansfield, LJ Doghramji, ND Adappa, JN Palmer, ...
Journal of Biological Chemistry 293 (25), 9824-9840, 2018
942018
TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis
ND Adappa, D Farquhar, JN Palmer, DW Kennedy, L Doghramji, ...
International forum of allergy & rhinology 6 (1), 25-33, 2016
942016
The emerging role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis
RJ Lee, NA Cohen
American journal of rhinology & allergy 27 (4), 283-286, 2013
942013
cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways
RJ Lee, JK Foskett
The Journal of clinical investigation 120 (9), 3137-3148, 2010
912010
Mechanisms of Ca2+-stimulated fluid secretion by porcine bronchial submucosal gland serous acinar cells
RJ Lee, JK Foskett
American Journal of Physiology-Lung Cellular and Molecular Physiology 298 (2 …, 2010
782010
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