Genomics and drug profiling of fatal TCF3-HLF−positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options U Fischer, M Forster, A Rinaldi, T Risch, S Sungalee, HJ Warnatz, ... Nature genetics 47 (9), 1020-1029, 2015 | 242 | 2015 |
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022 | 208 | 2022 |
Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans R Shinde, K Hezaveh, MJ Halaby, A Kloetgen, A Chakravarthy, ... Nature immunology 19 (6), 571-582, 2018 | 145 | 2018 |
MINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells G Doose, A Haake, SH Bernhart, C López, S Duggimpudi, F Wojciech, ... Proceedings of the National Academy of Sciences 112 (38), E5261-E5270, 2015 | 106 | 2015 |
CD8+ T cell priming in established chronic viral infection preferentially directs differentiation of memory-like cells for sustained immunity LM Snell, BL MacLeod, JC Law, I Osokine, HJ Elsaesser, K Hezaveh, ... Immunity 49 (4), 678-694. e5, 2018 | 104 | 2018 |
N6-methyladenosine reader YTHDF1 promotes ARHGEF2 translation and RhoA signaling in colorectal cancer S Wang, S Gao, Y Zeng, L Zhu, Y Mo, CC Wong, Y Bao, P Su, J Zhai, ... Gastroenterology 162 (4), 1183-1196, 2022 | 98 | 2022 |
GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment MJ Halaby, K Hezaveh, S Lamorte, MT Ciudad, A Kloetgen, BL MacLeod, ... Science immunology 4 (42), eaax8189, 2019 | 94 | 2019 |
Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis K Hezaveh, A Kloetgen, SH Bernhart, KD Mahapatra, D Lenze, J Richter, ... Haematologica 101 (11), 1380, 2016 | 48 | 2016 |
Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling S Duggimpudi, A Kloetgen, SK Maney, PC Münch, K Hezaveh, ... Journal of Biological Chemistry 293 (40), 15359-15369, 2018 | 35 | 2018 |
Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection LM Snell, W Xu, D Abd-Rabbo, G Boukhaled, M Guo, BL Macleod, ... Nature immunology 22 (12), 1524-1537, 2021 | 32 | 2021 |
Ciudad MT, Quevedo R., Neufeld L., Liu ZQ, Jin R., et al. Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to … K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte Immunity 55 (2), 324-340, 2022 | 31 | 2022 |
T‐cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases M Doerrenberg, A Kloetgen, K Hezaveh, W Wössmann, K Bleckmann, ... Genes, Chromosomes and Cancer 56 (2), 159-167, 2017 | 24 | 2017 |
Ciudad MT MJ Halaby, K Hezaveh, S Lamorte Kloetgen A, MacLeod BL, Guo M, Chakravarthy A, Medina TDS, Ugel S, Tsirigos …, 2019 | 22 | 2019 |
Ciudad K Hezaveh, RS Shinde, A Klotgen, MJ Halaby, S Lamorte MT, Quevedo 1169, 324-340, 0 | 21 | |
Ciudad MJ Halaby, K Hezaveh, S Lamorte MT, Kloetgen, A., MacLeod, BL, Guo, M., Chakravarthy, A., Medina, TDS, Ugel …, 2019 | 19 | 2019 |
YBX1 indirectly targets heterochromatin-repressed inflammatory response-related apoptosis genes through regulating CBX5 mRNA A Kloetgen, S Duggimpudi, K Schuschel, K Hezaveh, D Picard, H Schaal, ... International Journal of Molecular Sciences 21 (12), 4453, 2020 | 14 | 2020 |
A network of immune and microbial modifications underlies viral persistence in the gastrointestinal tract BL Macleod, HJ Elsaesser, LM Snell, RJ Dickson, M Guo, K Hezaveh, ... Journal of Experimental Medicine 217 (12), 2020 | 7 | 2020 |
Alterations of miRNAs and miRNA-regulated mRNA expression in GC B cell lymphomas determined by integrative sequencing analysis. K Hezaveh, A Kloetgen, SH Bernhart, KD Mahapatra, D Lenze, J Richter, ... | 5 | 2016 |
ICGC MMML-Seq Project. 2016. Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing … K Hezaveh, A Kloetgen, SH Bernhart, KD Mahapatra, D Lenze, J Richter, ... Haematologica 101 (11), 1380-1389, 0 | 4 | |
EHMT2/G9a-Inhibition Reprograms Cancer-Associated Fibroblasts (CAFs) to a More Differentiated, Less Proliferative and Invasive State NC Wu, R Quevedo, M Nurse, K Hezaveh, H Liu, F Sun, J Muffat, Y Sun, ... bioRxiv, 2023.07. 17.549300, 2023 | 1 | 2023 |