| Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 1240 | 2020 |
| Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’study HJN Andreyev, AR Norman, D Cunningham, J Oates, BR Dix, ... British journal of cancer 85 (5), 692-696, 2001 | 1008 | 2001 |
| Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 453 | 2018 |
| Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database BA Thompson, AB Spurdle, JP Plazzer, MS Greenblatt, K Akagi, ... Nature genetics 46 (2), 107-115, 2014 | 420 | 2014 |
| Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis S Hagan, F Al-Mulla, E Mallon, K Oien, R Ferrier, B Gusterson, JJC García, ... Clinical Cancer Research 11 (20), 7392-7397, 2005 | 311 | 2005 |
| KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression C Oliveira, S Velho, C Moutinho, A Ferreira, A Preto, E Domingo, ... Oncogene 26 (1), 158-163, 2007 | 273 | 2007 |
| Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts M Pupo, A Pisano, R Lappano, MF Santolla, EM De Francesco, ... Environmental health perspectives 120 (8), 1177-1182, 2012 | 272 | 2012 |
| Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ... Carcinogenesis 36 (Suppl_1), S254-S296, 2015 | 270 | 2015 |
| ENIGMA—evidence‐based network for the interpretation of germline mutant alleles: An international initiative to evaluate risk and clinical significance associated with … AB Spurdle, S Healey, A Devereau, FBL Hogervorst, ANA Monteiro, ... Human mutation 33 (1), 2-7, 2012 | 270 | 2012 |
| Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer G Ren, S Baritaki, H Marathe, J Feng, S Park, S Beach, PS Bazeley, ... Cancer research 72 (12), 3091-3104, 2012 | 224 | 2012 |
| Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes MS Bitar, S Wahid, S Mustafa, E Al-Saleh, GS Dhaunsi, F Al-Mulla European journal of pharmacology 511 (1), 53-64, 2005 | 218 | 2005 |
| The order of genetic events associated with colorectal cancer progression inferred from meta‐analysis of copy number changes CB Diep, K Kleivi, FR Ribeiro, MR Teixeira, OC Lindgjærde, RA Lothe Genes, Chromosomes and Cancer 45 (1), 31-41, 2006 | 205 | 2006 |
| Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients F Al-Mulla, S Hagan, AI Behbehani, MS Bitar, SS George, JJ Going, ... Journal of Clinical Oncology 24 (36), 5672-5679, 2006 | 194 | 2006 |
| Environmental immune disruptors, inflammation and cancer risk PA Thompson, M Khatami, CJ Baglole, J Sun, SA Harris, EY Moon, ... Carcinogenesis 36 (Suppl_1), S232-S253, 2015 | 168 | 2015 |
| Comparative genomic hybridization analysis of primary colorectal carcinomas and their synchronous metastases F Al‐Mulla, WN Keith, IR Pickford, JJ Going, GD Birnie Genes, Chromosomes and Cancer 24 (4), 306-314, 1999 | 164 | 1999 |
| The role of lipid metabolism in COVID-19 virus infection and as a drug target M Abu-Farha, TA Thanaraj, MG Qaddoumi, A Hashem, J Abubaker, ... International journal of molecular sciences 21 (10), 3544, 2020 | 162 | 2020 |
| Causes of genome instability: the effect of low dose chemical exposures in modern society SAS Langie, G Koppen, D Desaulniers, F Al-Mulla, R Al-Temaimi, ... Carcinogenesis 36 (Suppl_1), S61-S88, 2015 | 157 | 2015 |
| Heterogeneity of mutant versus wild‐type Ki‐ras in primary and metastatic colorectal carcinomas, and association of codon‐12 valine with early mortality F Al‐Mulla, JJ Going, ETHH Sowden, A Winter, IR Pickford, GD Birnie The Journal of Pathology: A Journal of the Pathological Society of Great …, 1998 | 146 | 1998 |
| Estrogen receptor silencing induces epithelial to mesenchymal transition in human breast cancer cells S Al Saleh, F Al Mulla, YA Luqmani PloS one 6 (6), e20610, 2011 | 140 | 2011 |
| Could the D614G substitution in the SARS-CoV-2 spike (S) protein be associated with higher COVID-19 mortality? M Eaaswarkhanth, A Al Madhoun, F Al-Mulla International Journal of Infectious Diseases 96, 459-460, 2020 | 135 | 2020 |
Jehad AbubakerSenior scientist and Head of Biochemistry and Molecular Biology unit at Dasman Diabetes InstituteVerified email at dasmaninstitute.org
