Thomas Sandmann
Thomas Sandmann
Computational biologist, Denali Therapeutics, South San Francisco, USA
Verified email at - Homepage
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A core transcriptional network for early mesoderm development in Drosophila melanogaster
T Sandmann, C Girardot, M Brehme, W Tongprasit, V Stolc, EEM Furlong
Genes & development 21 (4), 436-449, 2007
Patients with proneural glioblastoma may derive overall survival benefit from the addition of bevacizumab to first-line radiotherapy and temozolomide: retrospective analysis of …
T Sandmann, R Bourgon, J Garcia, C Li, T Cloughesy, OL Chinot, W Wick, ...
Journal of clinical oncology 33 (25), 2735, 2015
A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development
T Sandmann, LJ Jensen, JS Jakobsen, MM Karzynski, MP Eichenlaub, ...
Developmental cell 10 (6), 797-807, 2006
Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells
O Voloshanenko, G Erdmann, TD Dubash, I Augustin, M Metzig, G Moffa, ...
Nature communications 4 (1), 1-13, 2013
Mapping of signaling networks through synthetic genetic interaction analysis by RNAi
T Horn, T Sandmann, B Fischer, E Axelsson, W Huber, M Boutros
Nature methods 8 (4), 341-346, 2011
TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge
AA Nugent, K Lin, B Van Lengerich, S Lianoglou, L Przybyla, SS Davis, ...
Neuron 105 (5), 837-854. e9, 2020
The head-regeneration transcriptome of the planarian Schmidtea mediterranea
T Sandmann, MC Vogg, S Owlarn, M Boutros, K Bartscherer
Genome biology 12 (8), 1-19, 2011
Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes
M Pfeifer, B Zheng, T Erdmann, H Koeppen, R McCord, M Grau, A Staiger, ...
Leukemia 29 (7), 1578-1586, 2015
Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells
A Kathagen, A Schulte, G Balcke, HS Phillips, T Martens, J Matschke, ...
Acta neuropathologica 126 (5), 763-780, 2013
ChIP-on-chip protocol for genome-wide analysis of transcription factor binding in Drosophila melanogaster embryos
T Sandmann, JS Jakobsen, EEM Furlong
Nature protocols 1 (6), 2839-2855, 2006
Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network
JS Jakobsen, M Braun, J Astorga, EH Gustafson, T Sandmann, ...
Genes & development 21 (19), 2448-2460, 2007
Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in Drosophila
E Havula, M Teesalu, T Hyötyläinen, H Seppälä, K Hasygar, P Auvinen, ...
PLoS genetics 9 (4), e1003438, 2013
Randomized, double-blind, placebo-controlled, multicenter phase II study of onartuzumab plus bevacizumab versus placebo plus bevacizumab in patients with recurrent glioblastoma …
T Cloughesy, G Finocchiaro, C Belda-Iniesta, L Recht, AA Brandes, ...
Journal of clinical oncology 35 (3), 343-351, 2017
A map of directional genetic interactions in a metazoan cell
B Fischer, T Sandmann, T Horn, M Billmann, V Chaudhary, W Huber, ...
Elife 4, e05464, 2015
Design and evaluation of genome-wide libraries for RNA interference screens
T Horn, T Sandmann, M Boutros
Genome biology 11 (6), 1-12, 2010
Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia
BJ Andreone, L Przybyla, C Llapashtica, A Rana, SS Davis, ...
Nature Neuroscience 23 (8), 927-938, 2020
Mondo-Mlx mediates organismal sugar sensing through the Gli-similar transcription factor sugarbabe
J Mattila, E Havula, E Suominen, M Teesalu, I Surakka, R Hynynen, ...
Cell reports 13 (2), 350-364, 2015
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
JC Ullman, A Arguello, JA Getz, A Bhalla, CS Mahon, J Wang, T Giese, ...
Science Translational Medicine 12 (545), eaay1163, 2020
Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter
X Qu, T Sandmann, H Frierson, L Fu, E Fuentes, K Walter, K Okrah, ...
Oncogene 35 (50), 6403-6415, 2016
Suppression of Coatomer Mutants by a New Protein Family with COPI and COPII Binding Motifs in Saccharomyces cerevisiae
T Sandmann, JM Herrmann, J Dengjel, H Schwarz, A Spang
Molecular biology of the cell 14 (8), 3097-3113, 2003
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