| A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity M Silva, Y Kato, MB Melo, I Phung, BL Freeman, Z Li, K Roh, ... Science immunology 6 (66), eabf1152, 2021 | 89 | 2021 |
| Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ... Proceedings of the National Academy of Sciences 118 (38), e2106845118, 2021 | 79 | 2021 |
| Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity BL Hartwell, MB Melo, P Xiao, AA Lemnios, N Li, JYH Chang, J Yu, ... Science translational medicine 14 (654), eabn1413, 2022 | 56 | 2022 |
| Multivalent nanomaterials: learning from vaccines and progressing to antigen-specific immunotherapies BL Hartwell, L Antunez, BP Sullivan, S Thati, JO Sestak, C Berkland Journal of pharmaceutical sciences 104 (2), 346-361, 2015 | 49 | 2015 |
| Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis JO Sestak, BP Sullivan, S Thati, L Northrup, B Hartwell, L Antunez, ... Molecular Therapy-Methods & Clinical Development 1, 2014 | 45 | 2014 |
| Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis BL Hartwell, CJ Pickens, M Leon, L Northrup, MA Christopher, JD Griffin, ... Journal of autoimmunity 93, 76-88, 2018 | 35 | 2018 |
| Co-delivery of autoantigen and b7 pathway modulators suppresses experimental autoimmune encephalomyelitis L Northrup, JO Sestak, BP Sullivan, S Thati, BL Hartwell, TJ Siahaan, ... The AAPS journal 16, 1204-1213, 2014 | 33 | 2014 |
| Multivalent soluble antigen arrays exhibit high avidity binding and modulation of B cell receptor-mediated signaling to drive efficacy against experimental autoimmune … BL Hartwell, CJ Pickens, M Leon, C Berkland Biomacromolecules 18 (6), 1893-1907, 2017 | 30 | 2017 |
| Antigen-specific binding of multivalent soluble antigen arrays induces receptor clustering and impedes B cell receptor mediated signaling BL Hartwell, FJ Martinez-Becerra, J Chen, H Shinogle, M Sarnowski, ... Biomacromolecules 17 (3), 710-722, 2016 | 30 | 2016 |
| Routes of administration and dose optimization of soluble antigen arrays in mice with experimental autoimmune encephalomyelitis S Thati, C Kuehl, B Hartwell, J Sestak, T Siahaan, ML Forrest, C Berkland Journal of pharmaceutical sciences 104 (2), 714-721, 2015 | 27 | 2015 |
| Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates JT Martin, BL Hartwell, SC Kumarapperuma, MB Melo, DG Carnathan, ... Biomaterials 275, 120868, 2021 | 26 | 2021 |
| Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ... BioRxiv, 2021 | 19 | 2021 |
| Co-delivery of autoantigen and dexamethasone in incomplete Freund's adjuvant ameliorates experimental autoimmune encephalomyelitis L Northrup, JD Griffin, MA Christopher, LR Antunez, BL Hartwell, ... Journal of Controlled Release 266, 156-165, 2017 | 14 | 2017 |
| Molecular dynamics of multivalent soluble antigen arrays support a two-signal co-delivery mechanism in the treatment of experimental autoimmune encephalomyelitis BL Hartwell, A Smalter Hall, D Swafford, BP Sullivan, A Garza, JO Sestak, ... Molecular pharmaceutics 13 (2), 330-343, 2016 | 13 | 2016 |
| Smalter Hall BL Hartwell Swafford D, Sullivan BP, Garza A, Sestak JO, Northrup L, and Berkland C, 2016 | 12 | 2016 |
| Acute B-cell inhibition by soluble antigen arrays is valency-dependent and predicts immunomodulation in splenocytes JD Griffin, MA Leon, JR Salash, M Shao, BL Hartwell, CJ Pickens, ... Biomacromolecules 20 (5), 2115-2122, 2019 | 9 | 2019 |
| Screening immunomodulators to skew the antigen-specific autoimmune response L Northrup, BP Sullivan, BL Hartwell, A Garza, C Berkland Molecular pharmaceutics 14 (1), 66-80, 2017 | 7 | 2017 |
| Elucidating Vaccine Trafficking Mechanisms using Multimodal Imaging BL Hartwell, J Martin, JYH Chang, SC Kumarapperuma, RM Ruprecht, ... Microscopy and Microanalysis 29 (Supplement_1), 1068-1068, 2023 | 1 | 2023 |
| Harnessing the potential of the NALT and BALT as targets for immunomodulation using engineering strategies to enhance mucosal uptake ML Seefeld, EL Templeton, JM Lehtinen, N Sinclair, D Yadav, BL Hartwell Frontiers in Immunology 15, 1419527, 2024 | | 2024 |
| Transmucosal amphiphile-protein conjugate vaccine DJ Irvine, BL Hartwell US Patent App. 18/117,752, 2023 | | 2023 |
