| Acceleration of diabetic wound healing using a novel protease–anti-protease combination therapy M Gao, TT Nguyen, MA Suckow, WR Wolter, M Gooyit, S Mobashery, ... Proceedings of the National Academy of Sciences 112 (49), 15226-15231, 2015 | 161 | 2015 |
| Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury O Hadass, BN Tomlinson, M Gooyit, S Chen, JJ Purdy, JM Walker, ... PloS one 8 (10), e76904, 2013 | 120 | 2013 |
| A chemical biological strategy to facilitate diabetic wound healing M Gooyit, Z Peng, WR Wolter, H Pi, D Ding, D Hesek, M Lee, B Boggess, ... ACS chemical biology 9 (1), 105-110, 2014 | 91 | 2014 |
| Disarming Pseudomonas aeruginosa virulence factor LasB by leveraging a Caenorhabditis elegans infection model J Zhu, X Cai, TL Harris, M Gooyit, M Wood, M Lardy, KD Janda Chemistry & biology 22 (4), 483-491, 2015 | 57 | 2015 |
| Selective water-soluble gelatinase inhibitor prodrugs M Gooyit, M Lee, VA Schroeder, M Ikejiri, MA Suckow, S Mobashery, ... Journal of medicinal chemistry 54 (19), 6676-6690, 2011 | 57 | 2011 |
| Substituted 4-hydroxy-1, 2, 3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches AC Pippione, F Dosio, A Ducime, A Federico, K Martina, S Sainas, ... MedChemComm 6 (7), 1285-1292, 2015 | 53 | 2015 |
| Reprofiled anthelmintics abate hypervirulent stationary-phase Clostridium difficile M Gooyit, KD Janda Scientific reports 6 (1), 33642, 2016 | 51 | 2016 |
| O-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood–Brain Barrier M Gooyit, W Song, KV Mahasenan, K Lichtenwalter, MA Suckow, ... Journal of medicinal chemistry 56 (20), 8139-8150, 2013 | 40 | 2013 |
| Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier M Gooyit, MA Suckow, VA Schroeder, WR Wolter, S Mobashery, M Chang ACS Chemical Neuroscience 3 (10), 730-736, 2012 | 40 | 2012 |
| Dual Protonophore–Chitinase Inhibitors Dramatically Affect O. volvulus Molting M Gooyit, N Tricoche, S Lustigman, KD Janda Journal of Medicinal Chemistry 57 (13), 5792-5799, 2014 | 37 | 2014 |
| The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination C Marusak, I Bayles, J Ma, M Gooyit, M Gao, M Chang, B Bedogni Pharmacological research 113, 515-520, 2016 | 35 | 2016 |
| Influencing antibody-mediated attenuation of methamphetamine CNS distribution through vaccine linker design M Gooyit, PO Miranda, CJ Wenthur, A Ducime, KD Janda ACS chemical neuroscience 8 (3), 468-472, 2017 | 27 | 2017 |
| Water-soluble MMP-9 inhibitor reduces lesion volume after severe traumatic brain injury M Lee, Z Chen, BN Tomlinson, M Gooyit, D Hesek, MR Juárez, R Nizam, ... ACS chemical neuroscience 6 (10), 1658-1664, 2015 | 24 | 2015 |
| Synthesis, kinetic characterization and metabolism of diastereomeric 2‐(1‐(4‐phenoxyphenylsulfonyl) ethyl) thiiranes as potent gelatinase and MT1‐MMP inhibitors M Gooyit, M Lee, D Hesek, B Boggess, AG Oliver, R Fridman, ... Chemical biology & drug design 74 (6), 535-546, 2009 | 21 | 2009 |
| Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting M Gooyit, N Tricoche, S Javor, S Lustigman, KD Janda ACS Medicinal Chemistry Letters 6 (3), 339-343, 2015 | 20 | 2015 |
| Early gelatinase activity is not a determinant of long-term recovery after traumatic brain injury in the immature mouse BD Semple, LJ Noble-Haeusslein, M Gooyit, KG Tercovich, Z Peng, ... PLoS One 10 (11), e0143386, 2015 | 18 | 2015 |
| Water-soluble MMP-9 inhibitor prodrug generates active metabolites that cross the blood–brain barrier W Song, Z Peng, M Gooyit, MA Suckow, VA Schroeder, WR Wolter, M Lee, ... ACS chemical neuroscience 4 (8), 1168-1173, 2013 | 15 | 2013 |
| Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping M Gooyit, TL Harris, N Tricoche, S Javor, S Lustigman, KD Janda ACS Infectious Diseases 1 (5), 198-202, 2015 | 13 | 2015 |
| Limitations of knockout mice and other tools in assessment of the involvement of matrix metalloproteinases in wound healing and the means to overcome them TT Nguyen, WR Wolter, B Anderson, VA Schroeder, M Gao, M Gooyit, ... ACS Pharmacology & Translational Science 3 (3), 489-495, 2020 | 6 | 2020 |
| Modulation of the Surface-Layer Protein of Clostridium difficile through Cwp84 Inhibition MD Gooyit, KD Janda ACS Infectious Diseases 2 (7), 465-470, 2016 | 5 | 2016 |
