| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints J Bartkova, N Rezaei, M Liontos, P Karakaidos, D Kletsas, N Issaeva, ... Nature 444 (7119), 633-637, 2006 | 2282 | 2006 |
| Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage RG Syljuåsen, CS Sørensen, LT Hansen, K Fugger, C Lundin, ... Molecular and cellular biology, 2005 | 635 | 2005 |
| HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes S Bekker-Jensen, JR Danielsen, K Fugger, I Gromova, A Nerstedt, ... Nature cell biology 12 (1), 80-86, 2010 | 366 | 2010 |
| LEDGF (p75) promotes DNA-end resection and homologous recombination M Daugaard, A Baude, K Fugger, LK Povlsen, H Beck, CS Sørensen, ... Nature structural & molecular biology 19 (8), 803-810, 2012 | 217 | 2012 |
| Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations YW Chan, K Fugger, SC West Nature cell biology 20 (1), 92-103, 2018 | 170 | 2018 |
| SET8 is degraded via PCNA-coupled CRL4 (CDT2) ubiquitylation in S phase and after UV irradiation S Jørgensen, M Eskildsen, K Fugger, L Hansen, MS Yoo Larsen, ... Journal of cell biology 192 (1), 43-54, 2011 | 126 | 2011 |
| Repeat expansions confer WRN dependence in microsatellite-unstable cancers N van Wietmarschen, S Sridharan, WJ Nathan, A Tubbs, EM Chan, ... Nature 586 (7828), 292-298, 2020 | 115 | 2020 |
| FBH1 catalyzes regression of stalled replication forks K Fugger, M Mistrik, KJ Neelsen, Q Yao, R Zellweger, AN Kousholt, ... Cell reports 10 (10), 1749-1757, 2015 | 113 | 2015 |
| Human Fbh1 helicase contributes to genome maintenance via pro-and anti-recombinase activities K Fugger, M Mistrik, JR Danielsen, C Dinant, J Falck, J Bartek, J Lukas, ... Journal of Cell Biology 186 (5), 655-663, 2009 | 113 | 2009 |
| Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks S Bekker-Jensen, K Fugger, JR Danielsen, I Gromova, M Sehested, ... Journal of Biological Chemistry 282 (27), 19638-19643, 2007 | 99 | 2007 |
| FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress K Fugger, W Kit Chu, P Haahr, A Nedergaard Kousholt, H Beck, MJ Payne, ... Nature communications 4 (1), 1423, 2013 | 92 | 2013 |
| CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation AN Kousholt, K Fugger, S Hoffmann, BD Larsen, T Menzel, AA Sartori, ... Journal of Cell Biology 197 (7), 869-876, 2012 | 90 | 2012 |
| Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD G Hewitt, V Borel, S Segura-Bayona, T Takaki, P Ruis, R Bellelli, ... Molecular cell 81 (4), 767-783. e11, 2021 | 85 | 2021 |
| Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors K Fugger, I Bajrami, M Silva Dos Santos, SJ Young, S Kunzelmann, ... Science 372 (6538), 156-165, 2021 | 75 | 2021 |
| The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis P Burkovics, L Dome, S Juhasz, V Altmannova, M Sebesta, M Pacesa, ... Nucleic acids research 44 (7), 3176-3189, 2016 | 42 | 2016 |
| Tackling PARP inhibitor resistance K Fugger, G Hewitt, SC West, SJ Boulton Trends in cancer 7 (12), 1102-1118, 2021 | 30 | 2021 |
| Keeping homologous recombination in check K Fugger, SC West Cell Research 26 (4), 397-398, 2016 | 12 | 2016 |
| Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1 NJ Rzechorzek, S Kunzelmann, AG Purkiss, M Silva Dos Santos, ... Nature Communications 14 (1), 6809, 2023 | 1 | 2023 |
| Treatment of hr deficient cancer K Fugger, S West US Patent App. 17/640,706, 2022 | | 2022 |
