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Elenoe Smith
Elenoe Smith
Postdoctoral Fellow, Boston Children's Hospital
Verified email at bloodgroup.tch.harvard.edu
Title
Cited by
Cited by
Year
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ...
Nature, 2015
8902015
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
DE Bauer, SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, ...
Science 342 (6155), 253-257, 2013
6602013
Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes
Y Gao, E Smith, E Ker, P Campbell, E Cheng, S Zou, S Lin, L Wang, ...
Developmental cell 22 (3), 573-584, 2012
972012
ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets
LA Truman, KL Bentley, EC Smith, SA Massaro, DG Gonzalez, ...
The American journal of pathology 180 (4), 1715-1725, 2012
952012
Chronic myelogenous leukemia–initiating cells require Polycomb group protein EZH2
H Xie, C Peng, J Huang, BE Li, W Kim, EC Smith, Y Fujiwara, J Qi, ...
Cancer Discovery 6 (11), 1237-1247, 2016
892016
MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation
EC Smith, JN Thon, MT Devine, S Lin, VP Schulz, Y Guo, SA Massaro, ...
Blood 120 (11), 2317-2329, 2012
722012
Myocardin Related Transcription Factors Promote Megakaryocyte Maturation and Platelet Formation
EC Smith
YALE UNIVERSITY, 2012
70*2012
Hemoglobin genetics: recent contributions of GWAS and gene editing
EC Smith, SH Orkin
Human Molecular Genetics, ddw170, 2016
532016
Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activation
EC Smith, AM Teixeira, RC Chen, L Wang, Y Gao, KL Hahn, DS Krause
Blood 121 (7), 1094-1101, 2013
492013
Strict in vivo specificity of the Bcl11a erythroid enhancer
EC Smith, S Luc, DM Croney, MB Woodworth, LC Greig, Y Fujiwara, ...
Blood 128 (19), 2338-2342, 2016
462016
Hinge residue I174 is critical for proper dNTP selection by DNA polymerase β
J Yamtich, D Starcevic, J Lauper, E Smith, I Shi, S Rangarajan, J Jaeger, ...
Biochemistry 49 (11), 2326-2334, 2010
312010
Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing)
DE Bauer, MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, ...
Blood 126 (23), 638-638, 2015
72015
Identification of BCL11A structure-function domains for fetal hemoglobin silencing
DE Bauer, C Peng, EC Smith, SH Orkin
Blood 122 (21), 435-435, 2013
42013
Fine-Mapping and Genome Editing Reveal An Essential Erythroid Enhancer At The HbF-Associated BCL11A Locus
SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, MC Canver, ...
Blood 122 (21), 437-437, 2013
22013
HHS Public Access
MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem
Nature 527 (7577), 192-197, 2015
2015
MKL2 Functions in the Absence of MKL1 to Promote Megakaryocyte Maturation
EC Smith, JN Thon, SA Massaro, JE Italiano, D Krause
Blood 118 (21), 2336-2336, 2011
2011
Modeling Megakaryopoiesis and Leukemogenesis Using Human and Murine Embryonic Stem Cells
SA Massaro, EC Smith, M Iacovino, M Kyba, D Krause
Blood 116 (21), 2502-2502, 2010
2010
Serum Response Factor Is An Essential Transcription Factor in Megakaryocytic Maturation.
S Halene, Y Gao, K Hahn, E Smith, S Lin, AS Perkins, D Krause
Blood 114 (22), 3652-3652, 2009
2009
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