Rab Prinjha
Rab Prinjha
Verified email at gsk.com
Title
Cited by
Cited by
Year
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ...
Nature 478 (7370), 529-533, 2011
12752011
Suppression of inflammation by a synthetic histone mimic
E Nicodeme, KL Jeffrey, U Schaefer, S Beinke, S Dewell, C Chung, ...
Nature 468 (7327), 1119-1123, 2010
12532010
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
JP Cogswell, J Ward, IA Taylor, M Waters, Y Shi, B Cannon, K Kelnar, ...
Journal of Alzheimer's disease 14 (1), 27-41, 2008
8362008
Inhibitor of neurite outgrowth in humans
WFS Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G ...
Nature 403, 383-4, 2000
8172000
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
H Li, S Wetten, L Li, PLS Jean, R Upmanyu, L Surh, D Hosford, ...
Archives of neurology 65 (1), 45-53, 2008
5252008
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
SE Baranzini, J Wang, RA Gibson, N Galwey, Y Naegelin, F Barkhof, ...
Human molecular genetics 18 (4), 767-778, 2009
4922009
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ...
Molecular cell 51 (3), 310-325, 2013
4832013
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins
RJ Giger, JF Cloutier, A Sahay, RK Prinjha, DV Levengood, SE Moore, ...
Neuron 25 (1), 29-41, 2000
4522000
Cloning and functional expression of a human orthologue of rat vanilloid receptor-1
P Hayes, HJ Meadows, MJ Gunthorpe, MH Harries, DM Duckworth, ...
Pain 88 (2), 205-215, 2000
3492000
BET inhibitor resistance emerges from leukaemia stem cells
CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ...
Nature 525 (7570), 538-542, 2015
3342015
Discovery and characterization of small molecule inhibitors of the BET family bromodomains
C Chung, H Coste, JH White, O Mirguet, J Wilde, RL Gosmini, C Delves, ...
Journal of medicinal chemistry 54 (11), 3827-3838, 2011
3122011
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...
Nature chemical biology 11 (3), 189-191, 2015
3112015
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice
A Halper-Stromberg, CL Lu, F Klein, JA Horwitz, S Bournazos, L Nogueira, ...
Cell 158 (5), 989-999, 2014
3082014
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ...
Nature 514 (7523), 513-517, 2014
2702014
Suppression of the antiviral response by an influenza histone mimic
I Marazzi, JSY Ho, J Kim, B Manicassamy, S Dewell, RA Albrecht, ...
Nature 483 (7390), 428-433, 2012
2392012
Discovery of epigenetic regulator I-BET762: lead optimization to afford a clinical candidate inhibitor of the BET bromodomains
O Mirguet, R Gosmini, J Toum, CA Clément, M Barnathan, JM Brusq, ...
Journal of medicinal chemistry 56 (19), 7501-7515, 2013
2292013
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ...
Nature immunology 12 (1), 29-36, 2011
2242011
Place your BETs: the therapeutic potential of bromodomains
RK Prinjha, J Witherington, K Lee
Trends in pharmacological sciences 33 (3), 146-153, 2012
2152012
Myelin-associated glycoprotein interacts with ganglioside GT1b A mechanism for neurite outgrowth inhibition
M Vinson, PJLM Strijbos, A Rowles, L Facci, SE Moore, DL Simmons, ...
Journal of Biological Chemistry 276 (23), 20280-20285, 2001
2112001
Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis
L Dupuis, JLG de Aguilar, F di Scala, F Rene, M de Tapia, PF Pradat, ...
Neurobiology of disease 10 (3), 358-365, 2002
1842002
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