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Albert M. Berghuis
Albert M. Berghuis
Distinguished James McGill Professor of Biochemistry, Microbiology & Immunology, McGill University
Verified email at mcgill.ca
Title
Cited by
Cited by
Year
Structures of active conformations of Gi-alpha1 and the mechanism of GTP hydrolysis
DE Coleman, AM Berghuis, E Lee, ME Linder, AG Gilman, SR Sprangt
Science 265, 1405, 1994
11261994
Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold
RB Sutton, BA Davletov, AM Berghuis, TC Sudhof, SR Sprang
Cell 80 (6), 929-938, 1995
9201995
IRF8 mutations and human dendritic-cell immunodeficiency
S Hambleton, S Salem, J Bustamante, V Bigley, S Boisson-Dupuis, ...
New England Journal of Medicine 365 (2), 127-138, 2011
6552011
Oxidation state-dependent conformational changes in cytochrome c
AM Berghuis, GD Brayer
Journal of molecular biology 223 (4), 959-976, 1992
4721992
Tertiary and quaternary structural changes in Giα1 induced by GTP hydrolysis
MB Mixon, E Lee, DE Coleman, AM Berghuis, AG Gilman, SR Sprang
Science 270 (5238), 954-960, 1995
4011995
Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases
WC Hon, GA McKay, PR Thompson, RM Sweet, DSC Yang, GD Wright, ...
Cell 89 (6), 887-895, 1997
2941997
Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography
TK Sixma, SME Pronk, KH Kalk, BAM van Zanten, AM Berghuis, WGJ Hol
Nature 355 (6360), 561-564, 1992
2511992
Aminoglycoside antibiotics: structures, functions, and resistance
GD Wright, AM Berghuis, S Mobashery
Resolving the antibiotic paradox: progress in understanding drug resistance …, 1998
2151998
Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry
DH Fong, AM Berghuis
The EMBO journal, 2002
2122002
Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor
IA Mirza, BJ Yachnin, S Wang, S Grosse, H Bergeron, A Imura, H Iwaki, ...
Journal of the American Chemical Society 131 (25), 8848-8854, 2009
2082009
Crystal structure of an aminoglycoside 6′-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold
LE Wybenga-Groot, K Draker, GD Wright, AM Berghuis
Structure 7 (5), 497-507, 1999
1761999
Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors
B Rivera, T Gayden, J Carrot-Zhang, J Nadaf, T Boshari, D Faury, ...
Acta neuropathologica 131, 847-863, 2016
1682016
A recurrent PDGFRB mutation causes familial infantile myofibromatosis
YH Cheung, T Gayden, PM Campeau, CA LeDuc, D Russo, VH Nguyen, ...
The American Journal of Human Genetics 92 (6), 996-1000, 2013
1572013
A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni
S Bernatchez, CM Szymanski, N Ishiyama, J Li, HC Jarrell, PC Lau, ...
Journal of Biological Chemistry 280 (6), 4792-4802, 2005
1572005
The Role of a Conserved Internal Water Molecule and Its Associated Hydrogen Bond Network in Cytochrfome c
AM Berghuis, JG Guillemette, G McLendon, F Sherman, M Smith, ...
Journal of molecular biology 236 (3), 786-799, 1994
1331994
Structural Analyses of Nucleotide Binding to an Aminoglycoside Phosphotransferase,
DL Burk, WC Hon, AKW Leung, AM Berghuis
Biochemistry 40 (30), 8756-8764, 2001
1282001
Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b
P Peschard, G Kozlov, T Lin, IA Mirza, AM Berghuis, S Lipkowitz, M Park, ...
Molecular cell 27 (3), 474-485, 2007
1262007
Synthesis and Structure−Activity Relationships of Truncated Bisubstrate Inhibitors of Aminoglycoside 6‘-N-Acetyltransferases
F Gao, X Yan, T Shakya, OM Baettig, S Ait-Mohand-Brunet, AM Berghuis, ...
Journal of medicinal chemistry 49 (17), 5273-5281, 2006
1152006
Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis
CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ...
Cell 183 (6), 1617-1633. e22, 2020
1122020
Effect of the Asn52→ Ile mutation on the redox potential of yeast cytochrome c: theory and experiment
R Langen, GD Brayer, AM Berghuis, G McLendon, F Sherman, A Warshel
Journal of molecular biology 224 (3), 589-600, 1992
1121992
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