Todd E. Druley, MD, PhD
Todd E. Druley, MD, PhD
Mission Bio, Inc
Verified email at
Cited by
Cited by
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
T Litman, TE Druley, WD Stein, SE Bates
Cellular and Molecular Life Sciences CMLS 58, 931-959, 2001
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ...
Nature 518 (7540), 552-555, 2015
Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
AL Young, GA Challen, BM Birmann, TE Druley
Nature communications 7 (1), 12484, 2016
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
KL Bolton, RN Ptashkin, T Gao, L Braunstein, SM Devlin, D Kelly, M Patel, ...
Nature genetics 52 (11), 1219-1226, 2020
The evolutionary dynamics and fitness landscape of clonal hematopoiesis
CJ Watson, AL Papula, GYP Poon, WH Wong, AL Young, TE Druley, ...
Science 367 (6485), 1449-1454, 2020
Integrated analysis of germline and somatic variants in ovarian cancer
KL Kanchi, KJ Johnson, C Lu, MD McLellan, MDM Leiserson, MC Wendl, ...
Nature communications 5 (1), 3156, 2014
Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia
A Horani, TE Druley, MA Zariwala, AC Patel, BT Levinson, ...
The American Journal of Human Genetics 91 (4), 685-693, 2012
P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity
EB Mechetner, B Schott, BS Morse, WD Stein, T Druley, KA Davis, ...
Proceedings of the National Academy of Sciences 94 (24), 12908-12913, 1997
Quantification of rare allelic variants from pooled genomic DNA
TE Druley, FLM Vallania, DJ Wegner, KE Varley, OL Knowles, JA Bonds, ...
Nature methods 6 (4), 263-265, 2009
Surveillance recommendations for children with overgrowth syndromes and predisposition to Wilms tumors and hepatoblastoma
JM Kalish, L Doros, LJ Helman, RC Hennekam, RP Kuiper, SM Maas, ...
Clinical Cancer Research 23 (13), e115-e122, 2017
Single ABCA3 Mutations Increase Risk for Neonatal Respiratory Distress Syndrome
JA Wambach, DJ Wegner, K DePass, H Heins, TE Druley, RD Mitra, P An, ...
Pediatrics 130 (6), e1575-e1582, 2012
Recommendations for surveillance for children with leukemia-predisposing conditions
CC Porter, TE Druley, A Erez, RP Kuiper, K Onel, JD Schiffman, ...
Clinical Cancer Research 23 (11), e14-e22, 2017
Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1
CA Gurnett, DM Desruisseau, K McCall, R Choi, ZI Meyer, M Talerico, ...
Human molecular genetics 19 (7), 1165-1173, 2010
Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary …
R Chatterjee, E Ramos, M Hoffman, J VanWinkle, DR Martin, TK Davis, ...
Human genetics 131, 1725-1738, 2012
Clonal hematopoiesis and risk of acute myeloid leukemia
AL Young, RS Tong, BM Birmann, TE Druley
haematologica 104 (12), 2410, 2019
Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing
AL Young, TN Wong, AEO Hughes, SE Heath, TJ Ley, DC Link, TE Druley
Leukemia 29 (7), 1608-1611, 2015
Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease
SJ Matkovich, DJ Van Booven, A Hindes, MY Kang, TE Druley, ...
The Journal of clinical investigation 120 (1), 280-289, 2010
Genome wide association and linkage analyses identified three loci—4q25, 17q23. 2, and 10q11. 21—associated with variation in leukocyte telomere length: the Long Life Family …
JH Lee, R Cheng, LS Honig, M Feitosa, CM Kammerer, MS Kang, ...
Frontiers in genetics 4, 310, 2014
High-throughput discovery of rare insertions and deletions in large cohorts
FLM Vallania, TE Druley, E Ramos, J Wang, I Borecki, M Province, ...
Genome research 20 (12), 1711-1718, 2010
Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence
G Haller, T Druley, FL Vallania, RD Mitra, P Li, G Akk, JH Steinbach, ...
Human molecular genetics 21 (3), 647-655, 2012
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