Julian Knight
Julian Knight
Professor of Genomic Medicine, University of Oxford
Verified email at well.ox.ac.uk - Homepage
Cited by
Cited by
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution
SV Ramagopalan, A Heger, AJ Berlanga, NJ Maugeri, MR Lincoln, ...
Genome research 20 (10), 1352-1360, 2010
Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1* 1501 is regulated by vitamin D
SV Ramagopalan, NJ Maugeri, L Handunnetthi, MR Lincoln, SM Orton, ...
PLoS Genet 5 (2), e1000369, 2009
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
JC Knight, I Udalova, AVS Hill, BM Greenwood, N Peshu, K Marsh, ...
Nature genetics 22 (2), 145-150, 1999
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 2014
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ...
Nature genetics 44 (5), 502-510, 2012
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker, ...
The Lancet 396 (10249), 467-478, 2020
Major histocompatibility complex genomics and human disease
J Trowsdale, JC Knight
Annual review of genomics and human genetics 14, 301-323, 2013
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
J Bentham, DL Morris, DSC Graham, CL Pinder, P Tombleson, ...
Nature genetics 47 (12), 1457-1464, 2015
The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319 , a novel gene involved in neuronal migration
S Paracchini, A Thomas, S Castro, C Lai, M Paramasivam, Y Wang, ...
Human molecular genetics 15 (10), 1659-1666, 2006
Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
EE Davenport, KL Burnham, J Radhakrishnan, P Humburg, P Hutton, ...
The Lancet Respiratory Medicine 4 (4), 259-271, 2016
Regulatory polymorphisms underlying complex disease traits
JC Knight
Journal of molecular medicine 83 (2), 97-109, 2005
Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles
W McGuire, JC Knight, AVS Hill, CEM Allsopp, BM Greenwood, ...
The Journal of infectious diseases 179 (1), 287-290, 1999
In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading
JC Knight, BJ Keating, KA Rockett, DP Kwiatkowski
Nature genetics 33 (4), 469-475, 2003
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ...
Nature genetics 47 (7), 717-726, 2015
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization
K Bønnelykke, MC Matheson, TH Pers, R Granell, DP Strachan, AC Alves, ...
Nature genetics 45 (8), 902-906, 2013
Allele-specific gene expression uncovered
JC Knight
Trends in Genetics 20 (3), 113-116, 2004
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study
BP Scicluna, LA Van Vught, AH Zwinderman, MA Wiewel, EE Davenport, ...
The Lancet Respiratory medicine 5 (10), 816-826, 2017
Identification of common genetic variation that modulates alternative splicing
J Hull, S Campino, K Rowlands, MS Chan, RR Copley, MS Taylor, ...
PLoS Genet 3 (6), e99, 2007
Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility
D Hacking, JC Knight, K Rockett, H Brown, J Frampton, DP Kwiatkowski, ...
Genes & Immunity 5 (4), 274-282, 2004
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