Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1416 | 2013 |
A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution SV Ramagopalan, A Heger, AJ Berlanga, NJ Maugeri, MR Lincoln, ... Genome research 20 (10), 1352-1360, 2010 | 891 | 2010 |
Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1* 1501 is regulated by vitamin D SV Ramagopalan, NJ Maugeri, L Handunnetthi, MR Lincoln, SM Orton, ... PLoS Genet 5 (2), e1000369, 2009 | 594 | 2009 |
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria JC Knight, I Udalova, AVS Hill, BM Greenwood, N Peshu, K Marsh, ... Nature genetics 22 (2), 145-150, 1999 | 579 | 1999 |
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ... Science 343 (6175), 2014 | 568 | 2014 |
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ... Nature genetics 44 (5), 502-510, 2012 | 461 | 2012 |
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker, ... The Lancet 396 (10249), 467-478, 2020 | 455 | 2020 |
Major histocompatibility complex genomics and human disease J Trowsdale, JC Knight Annual review of genomics and human genetics 14, 301-323, 2013 | 410 | 2013 |
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus J Bentham, DL Morris, DSC Graham, CL Pinder, P Tombleson, ... Nature genetics 47 (12), 1457-1464, 2015 | 387 | 2015 |
The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319 , a novel gene involved in neuronal migration S Paracchini, A Thomas, S Castro, C Lai, M Paramasivam, Y Wang, ... Human molecular genetics 15 (10), 1659-1666, 2006 | 305 | 2006 |
Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study EE Davenport, KL Burnham, J Radhakrishnan, P Humburg, P Hutton, ... The Lancet Respiratory Medicine 4 (4), 259-271, 2016 | 302 | 2016 |
Regulatory polymorphisms underlying complex disease traits JC Knight Journal of molecular medicine 83 (2), 97-109, 2005 | 295 | 2005 |
Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles W McGuire, JC Knight, AVS Hill, CEM Allsopp, BM Greenwood, ... The Journal of infectious diseases 179 (1), 287-290, 1999 | 288 | 1999 |
In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading JC Knight, BJ Keating, KA Rockett, DP Kwiatkowski Nature genetics 33 (4), 469-475, 2003 | 284 | 2003 |
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ... Nature genetics 47 (7), 717-726, 2015 | 267 | 2015 |
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization K Bønnelykke, MC Matheson, TH Pers, R Granell, DP Strachan, AC Alves, ... Nature genetics 45 (8), 902-906, 2013 | 223 | 2013 |
Allele-specific gene expression uncovered JC Knight Trends in Genetics 20 (3), 113-116, 2004 | 212 | 2004 |
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study BP Scicluna, LA Van Vught, AH Zwinderman, MA Wiewel, EE Davenport, ... The Lancet Respiratory medicine 5 (10), 816-826, 2017 | 160 | 2017 |
Identification of common genetic variation that modulates alternative splicing J Hull, S Campino, K Rowlands, MS Chan, RR Copley, MS Taylor, ... PLoS Genet 3 (6), e99, 2007 | 159 | 2007 |
Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility D Hacking, JC Knight, K Rockett, H Brown, J Frampton, DP Kwiatkowski, ... Genes & Immunity 5 (4), 274-282, 2004 | 159 | 2004 |