Natalie J. Tatum
Natalie J. Tatum
Research Associate, Newcastle University
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The diverse structural landscape of quadruplexes
HL Lightfoot, T Hagen, NJ Tatum, J Hall
FEBS letters 593 (16), 2083-2102, 2019
Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition
DJ Wood, S Korolchuk, NJ Tatum, LZ Wang, JA Endicott, MEM Noble, ...
Cell chemical biology 26 (1), 121-130. e5, 2019
New active leads for tuberculosis booster drugs by structure-based drug discovery
NJ Tatum, JW Liebeschuetz, JC Cole, R Frita, A Herledan, AR Baulard, ...
Organic & Biomolecular Chemistry 15 (48), 10245-10255, 2017
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors
PA Lochhead, JA Tucker, NJ Tatum, J Wang, D Oxley, AM Kidger, ...
Nature communications 11 (1), 1-16, 2020
Structural and docking studies of potent ethionamide boosters
NJ Tatum, B Villemagne, N Willand, B Deprez, JW Liebeschuetz, ...
Acta Crystallographica Section C: Crystal Structure Communications 69 (11 …, 2013
Probing biological activity through structural modelling of ligand-receptor interactions of 2, 4-disubstituted thiazole retinoids
H Haffez, DR Chisholm, NJ Tatum, R Valentine, C Redfern, E Pohl, ...
Bioorganic & medicinal chemistry 26 (8), 1560-1572, 2018
Synthesis and molecular structure of a perfluorinated pyridyl carbanion
N Colgin, NJ Tatum, E Pohl, SL Cobb, G Sandford
Journal of Fluorine Chemistry 133, 33-37, 2012
Chatterboxes: the structural and functional diversity of cyclins
NJ Tatum, JA Endicott
Seminars in cell & developmental biology 107, 4-20, 2020
Relative Binding Energies Predict Crystallographic Binding Modes of Ethionamide Booster Lead Compounds
NJ Tatum, F Duarte, SCL Kamerlin, E Pohl
The Journal of Physical Chemistry Letters 10, 2244-2249, 2019
FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers
KA Mesquita, R Ali, R Doherty, MS Toss, I Miligy, A Alblihy, D Dorjsuren, ...
Cancers 13 (8), 1866, 2021
Synthesis, Ni (II) Schiff base complexation and structural analysis of fluorinated analogs of the ligand (S)-2-[N-(N′-benzylprolyl) amino] benzophenone (BPB)
NJ Tatum, DS Yufit, SL Cobb, CR Coxon
Journal of Fluorine Chemistry 173, 77-83, 2015
Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation
M Salamina, BC Montefiore, M Liu, DJ Wood, R Heath, JR Ault, LZ Wang, ...
Journal of molecular biology 433 (5), 166795, 2021
An Open-Source Molecular Builder and Free Energy Preparation Workflow
M Bieniek, B Cree, R Pirie, J Horton, N Tatum, D Cole
Discovery by virtual screening of ethionamide boosters for tuberculosis treatment
NJ Tatum
Durham University, 2015
Crystallographic Studies for Structure-Based Drug Design
Durham University, 2012
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