The diverse structural landscape of quadruplexes HL Lightfoot, T Hagen, NJ Tatum, J Hall FEBS letters 593 (16), 2083-2102, 2019 | 70 | 2019 |
Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition DJ Wood, S Korolchuk, NJ Tatum, LZ Wang, JA Endicott, MEM Noble, ... Cell chemical biology 26 (1), 121-130. e5, 2019 | 39 | 2019 |
New active leads for tuberculosis booster drugs by structure-based drug discovery NJ Tatum, JW Liebeschuetz, JC Cole, R Frita, A Herledan, AR Baulard, ... Organic & Biomolecular Chemistry 15 (48), 10245-10255, 2017 | 21 | 2017 |
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors PA Lochhead, JA Tucker, NJ Tatum, J Wang, D Oxley, AM Kidger, ... Nature communications 11 (1), 1-16, 2020 | 18 | 2020 |
Structural and docking studies of potent ethionamide boosters NJ Tatum, B Villemagne, N Willand, B Deprez, JW Liebeschuetz, ... Acta Crystallographica Section C: Crystal Structure Communications 69 (11 …, 2013 | 14 | 2013 |
Probing biological activity through structural modelling of ligand-receptor interactions of 2, 4-disubstituted thiazole retinoids H Haffez, DR Chisholm, NJ Tatum, R Valentine, C Redfern, E Pohl, ... Bioorganic & medicinal chemistry 26 (8), 1560-1572, 2018 | 12 | 2018 |
Synthesis and molecular structure of a perfluorinated pyridyl carbanion N Colgin, NJ Tatum, E Pohl, SL Cobb, G Sandford Journal of Fluorine Chemistry 133, 33-37, 2012 | 8 | 2012 |
Chatterboxes: the structural and functional diversity of cyclins NJ Tatum, JA Endicott Seminars in cell & developmental biology 107, 4-20, 2020 | 6 | 2020 |
Relative Binding Energies Predict Crystallographic Binding Modes of Ethionamide Booster Lead Compounds NJ Tatum, F Duarte, SCL Kamerlin, E Pohl The Journal of Physical Chemistry Letters 10, 2244-2249, 2019 | 5 | 2019 |
FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers KA Mesquita, R Ali, R Doherty, MS Toss, I Miligy, A Alblihy, D Dorjsuren, ... Cancers 13 (8), 1866, 2021 | 4 | 2021 |
Synthesis, Ni (II) Schiff base complexation and structural analysis of fluorinated analogs of the ligand (S)-2-[N-(N′-benzylprolyl) amino] benzophenone (BPB) NJ Tatum, DS Yufit, SL Cobb, CR Coxon Journal of Fluorine Chemistry 173, 77-83, 2015 | 4 | 2015 |
Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation M Salamina, BC Montefiore, M Liu, DJ Wood, R Heath, JR Ault, LZ Wang, ... Journal of molecular biology 433 (5), 166795, 2021 | 3 | 2021 |
An Open-Source Molecular Builder and Free Energy Preparation Workflow M Bieniek, B Cree, R Pirie, J Horton, N Tatum, D Cole | | 2022 |
Discovery by virtual screening of ethionamide boosters for tuberculosis treatment NJ Tatum Durham University, 2015 | | 2015 |
Crystallographic Studies for Structure-Based Drug Design N TATUM Durham University, 2012 | | 2012 |