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Mark J Pearson
Mark J Pearson
Verified email at aston.ac.uk - Homepage
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Year
Release of active peptidyl arginine deiminases by neutrophils can explain production of extracellular citrullinated autoantigens in rheumatoid arthritis synovial fluid
J Spengler, B Lugonja, A Jimmy Ytterberg, RA Zubarev, AJ Creese, ...
Arthritis & rheumatology 67 (12), 3135-3145, 2015
2392015
The hallmarks of osteoarthritis and the potential to develop personalised disease-modifying pharmacological therapeutics
DP Tonge, MJ Pearson, SW Jones
Osteoarthritis and cartilage 22 (5), 609-621, 2014
1872014
IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity
MJ Pearson, D Herndler-Brandstetter, MA Tariq, TA Nicholson, AM Philp, ...
Scientific reports 7 (1), 3451, 2017
1302017
Long intergenic noncoding RNAs mediate the human chondrocyte inflammatory response and are differentially expressed in osteoarthritis cartilage
MJ Pearson, AM Philp, JA Heward, BT Roux, DA Walsh, ET Davis, ...
Arthritis & rheumatology 68 (4), 845-856, 2016
1262016
Long noncoding RNAs in the regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis
MJ Pearson, SW Jones
Arthritis & rheumatology 68 (11), 2575-2583, 2016
992016
Regulation of the inflammatory synovial fibroblast phenotype by metastasis‐associated lung adenocarcinoma transcript 1 long noncoding RNA in obese patients with osteoarthritis
DE Nanus, SN Wijesinghe, MJ Pearson, MR Hadjicharalambous, ...
Arthritis & rheumatology 72 (4), 609-619, 2020
562020
Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts
MJ Pearson, MA Bik, C Ospelt, AJ Naylor, C Wehmeyer, SW Jones, ...
Scientific Reports 8 (1), 2018
372018
11β‐Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation
RS Hardy, CL Doig, Z Hussain, M O'Leary, SA Morgan, MJ Pearson, ...
The Journal of pathology 240 (4), 472-483, 2016
342016
The effects of cobalt–chromium–molybdenum wear debris in vitro on serum cytokine profiles and T cell repertoire
MJ Pearson, RL Williams, H Floyd, D Bodansky, LM Grover, ET Davis, ...
Biomaterials 67, 232-239, 2015
342015
Geometric confinement is required for recovery and maintenance of chondrocyte phenotype in alginate
ME Cooke, MJ Pearson, RJA Moakes, CJ Weston, ET Davis, SW Jones, ...
APL bioengineering 1 (1), 2017
172017
Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways
A Filer, P Antczak, GN Parsonage, HM Legault, M O’Toole, MJ Pearson, ...
PLoS One 10 (3), e0120917, 2015
162015
Bearings in hip arthroplasty: joint registries vs precision medicine
MJ Pearson, LM Grover, JM Lord, SW Jones, ET Davis
HSS Journal® 13 (1), 20-27, 2017
112017
Albumin 3′ untranslated region facilitates increased recombinant protein production from Chinese hamster ovary cells
MJ Pearson, S Khazaipoul, A Optun, IF Pryme, B Stern, JE Hesketh
Biotechnology Journal 7 (11), 1405-1411, 2012
42012
CUG binding protein 1 binds to a specific region within the human albumin 3′ untranslated region
S Khaziapoul, MJ Pearson, IF Pryme, B Stern, JE Hesketh
Biochemical and Biophysical Research Communications 426 (4), 539-543, 2012
42012
Evidence of intrinsic impairment of osteoblast phenotype at the curve apex in girls with adolescent idiopathic scoliosis
MJ Pearson, AM Philp, H Haq, ME Cooke, T Nicholson, LM Grover, ...
Spine Deformity 7, 533-542, 2019
32019
Characterisation of the biochemical and biophysical properties of biomimetic cartilage models
M Cooke, MJ Pearson, RL Williams, LM Grover, SW Jones
Osteoarthritis and Cartilage 24, S172-S173, 2016
32016
eNAMPT is localised to areas of cartilage damage in patients with hip osteoarthritis and drives cartilage catabolism leading to proteoglycan loss and inflammation
AM Philp, MJ Pearson, JM Lord, ET Davis, SW Jones
Osteoarthritis and Cartilage 24, S388, 2016
22016
The differential expression and functional role of long non coding RNAs in inflamed synovial tissue from patients with hip osteoarthritis
MJ Pearson, D Nanus, ET Davis, MA Lindsay, SW Jones
Osteoarthritis and Cartilage 26, S161, 2018
12018
OP0193 Synovial Fluid Neutrophils Undergoing Netosis Contribute to Joint Inflammation by Producing Citrullinated Autoantigens
J Spengler, B Lugonja, A Creese, A Nicholas, M Milward, M Pearson, ...
Annals of the Rheumatic Diseases 72 (Suppl 3), A118-A118, 2013
12013
A2. 16 Synovial Fluid Neutrophils Undergoing Netosis Contribute to Joint Inflammation by Producing Citrullinated Autoantigens
J Spengler, B Lugonja, A Creese, A Nicholas, M Milward, M Pearson, ...
Annals of the Rheumatic Diseases 72 (Suppl 1), A10-A10, 2013
12013
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