WAF1, a potential mediator of p53 tumor suppression WS El-Deiry, T Tokino, VE Velculescu, DB Levy, R Parsons, JM Trent, ... Cell 75 (4), 817-825, 1993 | 11132 | 1993 |
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer J Li, C Yen, D Liaw, K Podsypanina, S Bose, SI Wang, J Puc, C Miliaresis, ... science 275 (5308), 1943-1947, 1997 | 7122 | 1997 |
Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability S Markowitz, J Wang, L Myeroff, R Parsons, L Sun, J Lutterbaugh, RS Fan, ... Science 268 (5215), 1336-1338, 1995 | 3099 | 1995 |
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer FS Leach, NC Nicolaides, N Papadopoulos, B Liu, J Jen, R Parsons, ... Cell 75 (6), 1215-1225, 1993 | 2923 | 1993 |
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome D Liaw, DJ Marsh, J Li, PLM Dahia, SI Wang, Z Zheng, S Bose, KM Call, ... Nature genetics 16 (1), 64-67, 1997 | 2512 | 1997 |
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN M Tamura, J Gu, K Matsumoto, S Aota, R Parsons, KM Yamada Science 280 (5369), 1614-1617, 1998 | 1794 | 1998 |
The molecular basis of Turcot's syndrome SR Hamilton, B Liu, RE Parsons, N Papadopoulos, J Jen, SM Powell, ... New England Journal of Medicine 332 (13), 839-847, 1995 | 1448 | 1995 |
Hypermutability and mismatch repair deficiency in RER+ tumor cells R Parsons, GM Li, MJ Longley, W Fang, N Papadopoulos, J Jen, ... Cell 75 (6), 1227-1236, 1993 | 1367 | 1993 |
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems K Podsypanina, LH Ellenson, A Nemes, J Gu, M Tamura, KM Yamada, ... Proceedings of the National Academy of Sciences 96 (4), 1563-1568, 1999 | 1227 | 1999 |
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients B Liu, R Parsons, N Papadopoulos, NC Nicolaides, HT Lynch, P Watson, ... Nature medicine 2 (2), 169-174, 1996 | 1199 | 1996 |
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase MP Myers, JP Stolarov, C Eng, J Li, SI Wang, MH Wigler, R Parsons, ... Proceedings of the National Academy of Sciences 94 (17), 9052-9057, 1997 | 1154 | 1997 |
PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma LH Saal, K Holm, M Maurer, L Memeo, T Su, X Wang, JS Yu, ... Cancer research 65 (7), 2554-2559, 2005 | 1097 | 2005 |
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer R Parsons, LL Myeroff, B Liu, JKV Willson, SD Markowitz, KW Kinzler, ... Cancer research 55 (23), 5548-5550, 1995 | 1040 | 1995 |
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia T Palomero, ML Sulis, M Cortina, PJ Real, K Barnes, M Ciofani, ... Nature medicine 13 (10), 1203-1210, 2007 | 1039 | 2007 |
Mutations in PTEN Are Frequent in Endometrial Carcinoma But Rare in Other Common Gynecological Malignancies H Tashiro, MS Blazes, R Wu, KR Cho, S Bose, SI Wang, J Li, R Parsons, ... Cancer research 57 (18), 3935-3940, 1997 | 990 | 1997 |
PTEN: life as a tumor suppressor L Simpson, R Parsons Experimental cell research 264 (1), 29-41, 2001 | 976 | 2001 |
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability B Liu, NC Nicolaides, S Markowitz, JKV Willson, RE Parsons, J Jen, ... Nature genetics 9 (1), 48-55, 1995 | 973 | 1995 |
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation DJ Marsh, V Coulon, KL Lunetta, P Rocca-Serra, PLM Dahia, Z Zheng, ... Human molecular genetics 7 (3), 507-515, 1998 | 803 | 1998 |
Germline mutations in PTEN are present in Bannayan-Zonana syndrome DJ Marsh, PLM Dahia, Z Zheng, D Liaw, R Parsons, RJ Gorlin, C Eng Nature genetics 16 (4), 333-334, 1997 | 757 | 1997 |
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/− mice K Podsypanina, RT Lee, C Politis, I Hennessy, A Crane, J Puc, M Neshat, ... Proceedings of the National Academy of Sciences 98 (18), 10320-10325, 2001 | 751 | 2001 |