| The ubiquitin ligase CHIP integrates proteostasis and aging by regulation of insulin receptor turnover R Tawo, W Pokrzywa, É Kevei, ME Akyuz, V Balaji, S Adrian, J Höhfeld, ... Cell 169 (3), 470-482. e13, 2017 | 119 | 2017 |
| Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system A Segref, E Kevei, W Pokrzywa, K Schmeisser, J Mansfeld, ... Cell metabolism 19 (4), 642-652, 2014 | 116 | 2014 |
| The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans L Gazda, W Pokrzywa, D Hellerschmied, T Löwe, I Forné, ... Cell 152 (1), 183-195, 2013 | 115 | 2013 |
| The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington’s disease patients S Koyuncu, I Saez, HJ Lee, R Gutierrez-Garcia, W Pokrzywa, A Fatima, ... Nature Communications 9 (1), 2886, 2018 | 93 | 2018 |
| Targeting of Sna3p to the endosomal pathway depends on its interaction with Rsp5p and multivesicular body sorting on its ubiquitylation M Stawiecka‐Mirota, W Pokrzywa, J Morvan, T Zoladek, ... Traffic 8 (9), 1280-1296, 2007 | 83 | 2007 |
| Repair or destruction—an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis É Kevei, W Pokrzywa, T Hoppe Febs Letters 591 (17), 2616-2635, 2017 | 49 | 2017 |
| E4 ligase–specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis L Ackermann, M Schell, W Pokrzywa, É Kevei, A Gartner, B Schumacher, ... Nature structural & molecular biology 23 (11), 995-1002, 2016 | 42 | 2016 |
| Maintaining proteostasis under mechanical stress J Höhfeld, T Benzing, W Bloch, DO Fürst, S Gehlert, M Hesse, B Hoffmann, ... EMBO reports 22 (8), e52507, 2021 | 37 | 2021 |
| Pathogenic variants in the myosin chaperone UNC-45B cause progressive myopathy with eccentric cores S Donkervoort, CE Kutzner, Y Hu, X Lornage, J Rendu, T Stojkovic, ... The American Journal of Human Genetics 107 (6), 1078-1095, 2020 | 28 | 2020 |
| Ubiquitylation pathways in insulin signaling and organismal homeostasis V Balaji, W Pokrzywa, T Hoppe Bioessays 40 (5), 1700223, 2018 | 28 | 2018 |
| Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegans A Frumkin, S Dror, W Pokrzywa, Y Bar-Lavan, I Karady, T Hoppe, ... Frontiers in molecular biosciences 1, 21, 2014 | 27 | 2014 |
| Muscle‐derived exophers promote reproductive fitness M Turek, K Banasiak, M Piechota, N Shanmugam, M Macias, ... EMBO reports 22 (8), e52071, 2021 | 23 | 2021 |
| The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells A Fatima, D Irmak, A Noormohammadi, MM Rinschen, A Das, O Leidecker, ... Communications biology 3 (1), 262, 2020 | 22 | 2020 |
| The ubiquitin-selective chaperone Cdc48/p97 associates with Ubx3 to modulate monoubiquitylation of histone H2B M Bonizec, L Hérissant, W Pokrzywa, F Geng, S Wenzel, GC Howard, ... Nucleic acids research 42 (17), 10975-10986, 2014 | 21 | 2014 |
| Dual Sorting of the Saccharomyces cerevisiae Vacuolar Protein Sna4p W Pokrzywa, B Guerriat, J Dodzian, P Morsomme Eukaryotic cell 8 (3), 278-286, 2009 | 21 | 2009 |
| Ubiquitin signaling regulates RNA biogenesis, processing, and metabolism P Thapa, N Shanmugam, W Pokrzywa Bioessays 42 (1), 1900171, 2020 | 18 | 2020 |
| Chaperoning myosin assembly in muscle formation and aging W Pokrzywa, T Hoppe Worm 2 (3), 183-195, 2013 | 14 | 2013 |
| Impaired iron recycling from erythrocytes is an early hallmark of aging P Slusarczyk, PK Mandal, G Zurawska, M Niklewicz, K Chouhan, ... Elife 12, e79196, 2023 | 9 | 2023 |
| A heterotypic assembly mechanism regulates CHIP E3 ligase activity A Das, P Thapa, U Santiago, N Shanmugam, K Banasiak, K Dąbrowska, ... The EMBO Journal 41 (15), e109566, 2022 | 9 | 2022 |
| A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing V Balaji, L Müller, R Lorenz, É Kevei, WH Zhang, U Santiago, J Gebauer, ... Molecular Cell 82 (17), 3239-3254. e11, 2022 | 8 | 2022 |
Thorsten HoppeInstitute for Genetics and CECAD Cluster of ExcellenceVerified email at uni-koeln.de
