| NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice H Zhang, D Ryu, Y Wu, K Gariani, X Wang, P Luan, D D’Amico, ... Science 352 (6292), 1436-1443, 2016 | 1096 | 2016 |
| Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals PM Quirós, MA Prado, N Zamboni, D D’Amico, RW Williams, D Finley, ... J Cell Biol, jcb. 201702058, 2017 | 668 | 2017 |
| Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity V Sorrentino, M Romani, L Mouchiroud, JS Beck, H Zhang, D D’Amico, ... Nature, 2017 | 539 | 2017 |
| Impact of the Natural Compound Urolithin A on Health, Disease, and Aging D D’Amico, PA Andreux, P Valdés, A Singh, C Rinsch, J Auwerx Trends in Molecular Medicine, 2021 | 202 | 2021 |
| Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ... The EMBO journal 34 (2), 200-217, 2015 | 183 | 2015 |
| The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging D D’Amico, A Mottis, F Potenza, V Sorrentino, H Li, M Romani, V Lemos, ... Molecular Cell, 2019 | 113 | 2019 |
| Cytosolic Proteostasis Networks of the Mitochondrial Stress Response D D’Amico, V Sorrentino, J Auwerx Trends in Biochemical Sciences, 2017 | 113 | 2017 |
| Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy P Luan, D D’Amico, PA Andreux, PP Laurila, M Wohlwend, H Li, ... Science Translational Medicine 13 (588), 2021 | 104 | 2021 |
| Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults A Singh, D D’Amico, PA Andreux, AM Fouassier, W Blanco-Bose, ... Cell Reports Medicine 3 (5), 100633, 2022 | 87 | 2022 |
| Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial S Liu, D D’Amico, E Shankland, S Bhayana, JM Garcia, P Aebischer, ... JAMA Network Open 5 (1), e2144279-e2144279, 2022 | 83 | 2022 |
| Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons L Zheng, N Bernard-Marissal, N Moullan, D D’Amico, J Auwerx, DJ Moore, ... Human molecular genetics 26 (3), 582-598, 2017 | 82 | 2017 |
| Non-canonical Hedgehog/AMPK-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth D D’Amico, L Antonucci, L Di Magno, S Coni, G Sdruscia, A Macone, ... Developmental cell 35 (1), 21-35, 2015 | 78 | 2015 |
| Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy S Coni, L Antonucci, D D'Amico, L Di Magno, P Infante, E De Smaele, ... PLoS One 8 (6), e65718, 2013 | 77 | 2013 |
| Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the … A Singh, D D’Amico, PA Andreux, G Dunngalvin, T Kern, W Blanco-Bose, ... European Journal of Clinical Nutrition, 1-12, 2021 | 57 | 2021 |
| Urolithin A improves mitochondrial health, reduces cartilage degeneration, and alleviates pain in osteoarthritis D D'Amico, M Olmer, AM Fouassier, P Valdés, PA Andreux, C Rinsch, ... Aging Cell, e13662, 2022 | 55 | 2022 |
| Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth L Di Magno, D Manzi, D D’Amico, S Coni, A Macone, P Infante, ... Cell Cycle 13 (21), 3404-3413, 2014 | 54 | 2014 |
| The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint L Di Magno, A Basile, S Coni, S Manni, G Sdruscia, D D'Amico, ... Oncotarget 7 (8), 9538, 2016 | 49 | 2016 |
| T3 preserves ovarian granulosa cells from chemotherapy-induced apoptosis CV Falzacappa, E Timperi, B Bucci, D Amendola, P Piergrossi, D D'Amico, ... Journal of Endocrinology 215 (2), 281-289, 2012 | 40 | 2012 |
| Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation L Antonucci, L Di Magno, D D'amico, S Manni, SM Serrao, F Di Pastena, ... International Journal of Oncology, 0 | 32 | |
| CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMyc L Antonucci, D D'Amico, L Di Magno, S Coni, L Di Marcotullio, B Cardinali, ... Cell Cycle 13 (3), 434-439, 2014 | 20 | 2014 |
