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Benjamin Ryskeldi-Falcon
Benjamin Ryskeldi-Falcon
Group Leader, MRC Laboratory of Molecular Biology (LMB)
Verified email at mrc-lmb.cam.ac.uk - Homepage
Title
Cited by
Cited by
Year
Cryo-EM structures of tau filaments from Alzheimer’s disease
AWP Fitzpatrick, B Falcon, S He, AG Murzin, G Murshudov, HJ Garringer, ...
Nature 547 (7662), 185-190, 2017
17212017
Structures of filaments from Pick’s disease reveal a novel tau protein fold
B Falcon, W Zhang, A Murzin, G Murshudov, H Garringer, R Vidal, ...
Nature 561, 137-140, 2018
7022018
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
B Falcon, J Zivanov, W Zhang, AG Murzin, HJ Garringer, R Vidal, ...
Nature 568 (7752), 420-423, 2019
5872019
Structure-based classification of tauopathies
Y Shi, W Zhang, Y Yang, AG Murzin, B Falcon, A Kotecha, M van Beers, ...
Nature 598 (7880), 359-363, 2021
4742021
Novel tau filament fold in corticobasal degeneration
W Zhang, A Tarutani, KL Newell, AG Murzin, T Matsubara, B Falcon, ...
Nature 580 (7802), 283-287, 2020
4142020
Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer’s and Pick’s diseases
W Zhang, B Falcon, AG Murzin, J Fan, RA Crowther, M Goedert, ...
Elife 8, e43584, 2019
3952019
Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration
M Goedert, M Masuda-Suzukake, B Falcon
Brain 140 (2), 266-278, 2017
2982017
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
B Falcon, W Zhang, M Schweighauser, AG Murzin, R Vidal, HJ Garringer, ...
Acta neuropathologica 136 (5), 699-708, 2018
2862018
Conformation determines the seeding potencies of native and recombinant Tau aggregates
B Falcon, A Cavallini, R Angers, S Glover, TK Murray, L Barnham, ...
Journal of biological chemistry 290 (2), 1049-1065, 2015
2832015
Cryo-EM structures of amyloid-β 42 filaments from human brains
Y Yang, D Arseni, W Zhang, M Huang, S Lövestam, M Schweighauser, ...
Science 375 (6577), 167-172, 2022
2392022
Cryo-EM structures of tau filaments
SHW Scheres, W Zhang, B Falcon, M Goedert
Current Opinion in Structural Biology 64, 17-25, 2020
1802020
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation
WA McEwan, B Falcon, M Vaysburd, D Clift, AL Oblak, B Ghetti, ...
Proceedings of the National Academy of Sciences 114 (3), 574-579, 2017
1522017
Short fibrils constitute the major species of seed-competent tau in the brains of mice transgenic for human P301S tau
SJ Jackson, C Kerridge, J Cooper, A Cavallini, B Falcon, CV Cella, ...
Journal of Neuroscience 36 (3), 762-772, 2016
1482016
“Prion‐like” templated misfolding in tauopathies
F Clavaguera, I Lavenir, B Falcon, S Frank, M Goedert, M Tolnay
Brain pathology 23 (3), 342-349, 2013
1452013
Structure of pathological TDP-43 filaments from ALS with FTLD
D Arseni, M Hasegawa, AG Murzin, F Kametani, M Arai, M Yoshida, ...
Nature 601 (7891), 139-143, 2022
1402022
Prion-like mechanisms in the pathogenesis of tauopathies and synucleinopathies
M Goedert, B Falcon, F Clavaguera, M Tolnay
Current neurology and neuroscience reports 14, 1-11, 2014
1322014
Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607
Y Shi, AG Murzin, B Falcon, A Epstein, J Machin, P Tempest, KL Newell, ...
Acta neuropathologica 141, 697-708, 2021
1092021
Galectin-8–mediated selective autophagy protects against seeded tau aggregation
B Falcon, J Noad, H McMahon, F Randow, M Goedert
Journal of Biological Chemistry 293 (7), 2438-2451, 2018
1082018
Age-dependent formation of TMEM106B amyloid filaments in human brains
M Schweighauser, D Arseni, M Bacioglu, M Huang, S Lövestam, Y Shi, ...
Nature 605 (7909), 310-314, 2022
942022
Measurement of tau filament fragmentation provides insights into prion-like spreading
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, ...
ACS chemical neuroscience 9 (6), 1276-1282, 2018
782018
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