Christopher D McFarland
Christopher D McFarland
Assistant Professor in Genetics & Genome Sciences at Case Western University
Verified email at stanford.edu - Homepage
Title
Cited by
Cited by
Year
Impact of deleterious passenger mutations on cancer progression
CD McFarland, KS Korolev, GV Kryukov, SR Sunyaev, LA Mirny
Proceedings of the National Academy of Sciences 110 (8), 2910-2915, 2013
2552013
Tug-of-war between driver and passenger mutations in cancer and other adaptive processes
CD McFarland, LA Mirny, KS Korolev
Proceedings of the National Academy of Sciences 111 (42), 15138-15143, 2014
982014
The damaging effect of passenger mutations on cancer progression
CD McFarland, JA Yaglom, JW Wojtkowiak, JG Scott, DL Morse, ...
Cancer research 77 (18), 4763-4772, 2017
542017
A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo
ZN Rogers, CD McFarland, IP Winters, S Naranjo, CH Chuang, D Petrov, ...
Nature methods 14 (7), 737-742, 2017
452017
Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice
ZN Rogers, CD McFarland, IP Winters, JA Seoane, JJ Brady, S Yoon, ...
Nature genetics 50 (4), 483-486, 2018
432018
Massively parallel digital transcriptional profiling of single cells. Nat Commun 8: 14049
GX Zheng, JM Terry, P Belgrader, P Ryvkin, ZW Bent, R Wilson, ...
Molecular Therapy Untreated AdPNM Adloxp-PNM islets, 10-5, 2017
302017
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity
IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, ...
Nature communications 8 (1), 1-16, 2017
292017
Massively parallel digital transcriptional profiling of single cells. Nat Commun. 2017; 8: 14049
GXY Zheng, JM Terry, P Belgrader, P Ryvkin, ZW Bent, R Wilson, ...
HLA. DPB1 9, 0
26
An in vivo multiplexed small-molecule screening platform
BM Grüner, CJ Schulze, D Yang, D Ogasawara, MM Dix, ZN Rogers, ...
Nature methods 13 (10), 883-889, 2016
232016
Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer
JA Yaglom, C McFarland, L Mirny, MY Sherman
Oncotarget 5 (18), 8367, 2014
142014
A modified ziggurat algorithm for generating exponentially and normally distributed pseudorandom numbers
CD McFarland
Journal of Statistical Computation and Simulation, 1-14, 2015
42015
Passenger DNA alterations reduce cancer fitness in cell culture and mouse models
CD McFarland, JA Yaglom, JW Wojtkowiak, JG Scott, DL Morse, ...
BioRxiv, 026302, 2015
42015
Most cancers carry a substantial deleterious load due to Hill-Robertson interference
S Tilk, C Curtis, D Petrov, CD McFarland
bioRxiv, 764340, 2019
32019
Quantitative in vivo analyses reveal a complex pharmacogenomic landscape in lung adenocarcinoma
C Li, WY Lin, H Rizvi, H Cai, CD McFarland, ZN Rogers, M Yousefi, ...
BioRxiv, 2020
22020
The role of deleterious passengers in cancer
CD McFarland
22014
A genetic model of metastatic evolution: Driver and passenger mutations affect metastatic fitness
CD McFarland, JG Scott, D Basanta, ARA Anderson, LA Mirny
Cancer Research 71 (8 Supplement), 24-24, 2011
12011
Most cancers carry a substantial deleterious load due to Hill-Robertson interference
C McFarland, S Tilk, C Curtis, D Petrov
2020
Compositions and methods for multiplexed quantitative analysis of cell lineages
MM Winslow, D Petrov, IP Winters, C Mcfarland, ZN Rogers
US Patent 10,738,300, 2020
2020
Multiplexed functional cancer genomics.
H Cai, C Li, SK Chew, M Yousefi, G Foggetti, WY Lin, ZN Rogers, ...
CANCER RESEARCH 80 (11), 23-23, 2020
2020
Abstract IA26: Multiplexed functional cancer genomics
H Cai, C Li, SK Chew, M Yousefi, G Foggetti, WY Lin, ZN Rogers, ...
Cancer Research 80 (11 Supplement), IA26-IA26, 2020
2020
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