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Christopher D McFarland
Christopher D McFarland
Assistant Professor in Genetics & Genome Sciences at Case Western University
Verified email at case.edu - Homepage
Title
Cited by
Cited by
Year
Impact of deleterious passenger mutations on cancer progression
CD McFarland, KS Korolev, GV Kryukov, SR Sunyaev, LA Mirny
Proceedings of the National Academy of Sciences 110 (8), 2910-2915, 2013
3322013
Massively parallel digital transcriptional profiling of single cells. Nat. Commun. 8, 14049
GXY Zheng, JM Terry, P Belgrader, P Ryvkin, ZW Bent, R Wilson, ...
1692017
Tug-of-war between driver and passenger mutations in cancer and other adaptive processes
CD McFarland, LA Mirny, KS Korolev
Proceedings of the National Academy of Sciences 111 (42), 15138-15143, 2014
1622014
The damaging effect of passenger mutations on cancer progression
CD McFarland, JA Yaglom, JW Wojtkowiak, JG Scott, DL Morse, ...
Cancer research 77 (18), 4763-4772, 2017
1172017
A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo
ZN Rogers, CD McFarland, IP Winters, S Naranjo, CH Chuang, D Petrov, ...
Nature methods 14 (7), 737-742, 2017
1162017
Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice
ZN Rogers, CD McFarland, IP Winters, JA Seoane, JJ Brady, S Yoon, ...
Nature genetics 50 (4), 483-486, 2018
1122018
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity
IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, ...
Nature communications 8 (1), 2053, 2017
942017
Massively parallel digital transcriptional profiling of single cells. Nat Commun. 2017; 8: 14049
GXY Zheng, JM Terry, P Belgrader, P Ryvkin, ZW Bent, R Wilson, ...
722019
An in vivo multiplexed small-molecule screening platform
BM Grüner, CJ Schulze, D Yang, D Ogasawara, MM Dix, ZN Rogers, ...
Nature methods 13 (10), 883-889, 2016
622016
A functional taxonomy of tumor suppression in oncogenic KRAS–driven lung cancer
H Cai, SK Chew, C Li, MK Tsai, L Andrejka, CW Murray, NW Hughes, ...
Cancer discovery 11 (7), 1754-1773, 2021
342021
Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer
JA Yaglom, C McFarland, L Mirny, MY Sherman
Oncotarget 5 (18), 8367, 2014
232014
Most cancers carry a substantial deleterious load due to Hill-Robertson interference
S Tilk, S Tkachenko, C Curtis, DA Petrov, CD McFarland
elife 11, e67790, 2022
212022
Quantitative In Vivo Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma
C Li, WY Lin, H Rizvi, H Cai, CD McFarland, ZN Rogers, M Yousefi, ...
Cancer research 81 (17), 4570-4580, 2021
162021
Seasonal epidemiology of gastrointestinal nematodes of cattle in the northern continental climate zone of western Canada as revealed by internal transcribed spacer-2 ribosomal …
T Wang, EM Redman, A Morosetti, R Chen, S Kulle, N Morden, ...
Parasites & Vectors 14, 1-13, 2021
142021
An improved model for the population dynamics of cattle gastrointestinal nematodes on pasture: parameterisation and field validation for Ostertagia ostertagi and Cooperia …
T Wang, HR Vineer, E Redman, A Morosetti, R Chen, C McFarland, ...
Veterinary parasitology 310, 109777, 2022
92022
A modified ziggurat algorithm for generating exponentially and normally distributed pseudorandom numbers
CD McFarland
Journal of Statistical Computation and Simulation, 1-14, 2015
82015
Tracking gastrointestinal nematode risk on cattle farms through pasture contamination mapping
C McFarland, HR Vineer, L Chesney, N Henry, C Brown, P Airs, ...
International Journal for Parasitology 52 (10), 691-703, 2022
72022
The role of deleterious passengers in cancer
CD McFarland
Harvard University, 2014
72014
Novel epidemiological model of gastrointestinal nematode infection to assess grazing cattle resilience by integrating host growth, parasite, grass and environmental dynamics
JAN Filipe, I Kyriazakis, C McFarland, ER Morgan
International Journal for Parasitology 53 (3), 133-155, 2023
62023
Passenger DNA alterations reduce cancer fitness in cell culture and mouse models
CD McFarland, JA Yaglom, JW Wojtkowiak, JG Scott, DL Morse, ...
bioRxiv, 026302, 2015
62015
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