Targeting hallmarks of cancer to enhance radiosensitivity in gastrointestinal cancers AM Buckley, N Lynam-Lennon, H O’Neill, J O’Sullivan Nature reviews Gastroenterology & hepatology 17 (5), 298-313, 2020 | 190 | 2020 |
Evaluation of oncogenic cysteinyl leukotriene receptor 2 as a therapeutic target for uveal melanoma K Slater, PS Hoo, AM Buckley, JM Piulats, A Villanueva, A Portela, ... Cancer and Metastasis Reviews 37, 335-345, 2018 | 31 | 2018 |
Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma AM Buckley, N Lynam-Lennon, SA Kennedy, MR Dunne, JJ Aird, ... Oncotarget 9 (72), 33634, 2018 | 26 | 2018 |
Pyrazinib (P3),[(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma AM Buckley, MR Dunne, N Lynam-Lennon, SA Kennedy, A Cannon, ... Cancer letters 447, 115-129, 2019 | 22 | 2019 |
Characterisation of an isogenic model of cisplatin resistance in oesophageal adenocarcinoma cells AM Buckley, BAS Bibby, MR Dunne, SA Kennedy, MB Davern, ... Pharmaceuticals 12 (1), 33, 2019 | 14 | 2019 |
Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib AM Buckley, MR Dunne, ME Morrissey, SA Kennedy, A Nolan, M Davern, ... Scientific reports 10 (1), 12105, 2020 | 11 | 2020 |
1, 4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours CT Butler, SA Kennedy, A Buckley, R Doyle, E Conroy, WM Gallagher, ... Oncotarget 10 (38), 3725, 2019 | 7 | 2019 |
(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma. Cancer Lett. 2019; 447: 115–129. doi: 10.1016 … AM Buckley, MR Dunne, N Lynam-Lennon, SA Kennedy, A Cannon, ... CrossRef][Google Scholar], 0 | 7 | |
Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the Oesophagogastric Junction AB Heeran, J McCready, MR Dunne, NE Donlon, TS Nugent, A Bhardwaj, ... Metabolites 11 (11), 768, 2021 | 4 | 2021 |
Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model AB Heeran, HP Berrigan, CE Buckley, HM Bottu, O Prendiville, ... Translational Oncology 14 (1), 100882, 2021 | 4 | 2021 |
P095 Association between tissue oncostatin M expression and infliximab response in corticosteroid refractory acute severe ulcerative colitis J O'Connell, P McDonagh, N Clarke, A Buckley, C Dunne, K Hartery, ... Journal of Crohn's and Colitis 13 (Supplement_1), S133-S134, 2019 | 4 | 2019 |
Combining 1, 4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors SA Kennedy, ME Morrissey, MR Dunne, F O’Connell, CT Butler, ... BMC cancer 20, 1-14, 2020 | 3 | 2020 |
Colonic oncostatin M expression evaluated by immunohistochemistry and infliximab therapy outcome in corticosteroid-refractory acute severe ulcerative colitis J O’connell, J Doherty, A Buckley, D Cormican, C Dunne, K Hartery, ... Intestinal research 20 (3), 381, 2022 | 2 | 2022 |
Proteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinoma S Marcone, A Buckley, CJ Ryan, M McCabe, N Lynam-Lennon, ... Cancer Treatment and Research Communications 27, 100376, 2021 | 2 | 2021 |
A Deficiency in FKBPL Induces Obesity by Promoting NF-kappa B Induced Inflammation in Adipose Tissue S Annett, A Short, S Madden, B Cavangh, R Bennett, G Moore, ... OBESITY 28, 42-42, 2020 | | 2020 |
Enhancing treatment response to neo-adjuvant radiation therapy in oesophageal cancer using novel dual action drugs targeting tumour energy metabolism and angiogenesis AM Buckley University College Dublin, 2019 | | 2019 |
Association between tissue oncostatin M expression and infliximab response in corticosteroid refractory acute severe ulcerative colitis J O'Connell, P McDonagh, N Clarke, A Buckley, C Dunne, K Hartery, ... JOURNAL OF CROHNS & COLITIS 13, S134-S134, 2019 | | 2019 |
PS02. 174: THE ACTION OF A NOVEL RADIOSENSITISER WITHIN THE OESOPHAGEAL ADENOCARCINOMA TUMOUR MICROENVIROMENT A Buckley, N Lynam-Lennon, S Kennedy, A Cannon, D O’Toole, S Maher, ... Diseases of the Esophagus 31 (Supplement_1), 171-171, 2018 | | 2018 |
Loss of microRNA-7 leads to alpha synuclein accumulation and dopaminergic neuronal loss in vivo OC Llana, KJ McMillan, TK Murray, N Bengoa-Vergniory, J Cooper, ... The 41st Annual Meeting Japanese Neuroscience Society July 26-29, 2018, 2018 | | 2018 |
Identification of anti-angiogenic and anti-metabolic compounds in-vitro and in-vivo in zebrafish to determine if novel dual action drugs can enhance radiosensitivity in … A Buckley, NL Lennon, A Cannon, R Byrne, A Reynolds, JV Reynolds, ... European Journal of Cancer 1 (61), S118, 2016 | | 2016 |