James R Larkin
James R Larkin
Post-doctoral researcher, Department of Oncology, University of Oxford
Verified email at oncology.ox.ac.uk - Homepage
TitleCited byYear
High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease
PJ Thornalley, R Babaei-Jadidi, H Al Ali, N Rabbani, A Antonysunil, ...
Diabetologia 50 (10), 2164-2170, 2007
2412007
Accurate and reliable high-throughput detection of copy number variation in the human genome
H Fiegler, R Redon, D Andrews, C Scott, R Andrews, C Carder, R Clark, ...
Genome research 16 (12), 1566-1574, 2006
1632006
High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study
N Rabbani, SS Alam, S Riaz, JR Larkin, MW Akhtar, T Shafi, ...
Diabetologia 52 (2), 208-212, 2009
1612009
Recent advances in SALDI-MS techniques and their chemical and bioanalytical applications
KP Law, JR Larkin
Analytical and bioanalytical chemistry 399 (8), 2597-2622, 2011
1432011
ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1
Y Wang, F Bu, C Royer, S Serres, JR Larkin, MS Soto, NR Sibson, ...
Nature cell biology 16 (11), 1092, 2014
692014
A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis
AM Dickens, JR Larkin, JL Griffin, A Cavey, L Matthews, MR Turner, ...
Neurology 83 (17), 1492-1499, 2014
402014
Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates
S Melemenidis, A Jefferson, N Ruparelia, AM Akhtar, J Xie, D Allen, ...
Theranostics 5 (5), 515, 2015
362015
Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes
JR Larkin, F Zhang, L Godfrey, G Molostvov, D Zehnder, N Rabbani, ...
PLoS One 7 (12), e53175, 2012
322012
The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis
E Gray, JR Larkin, TDW Claridge, K Talbot, NR Sibson, MR Turner
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16 (7-8), 456-463, 2015
262015
High glucose causes a decrease in expression of thiamine transporters in human proximal tubule epithelial cells in vitro
JR Larkin, PJ Thornalley
Diabetologia 51, S97-S97, 2008
142008
Anti-inflammatory microglia/macrophages as a potential therapeutic target in brain metastasis
KE Andreou, MS Soto, D Allen, V Economopoulos, A de Bernardi, ...
Frontiers in oncology 7, 251, 2017
112017
Covalent assembly of nanoparticles as a peptidase-degradable platform for molecular MRI
F Perez-Balderas, SI Van Kasteren, AAA Aljabali, K Wals, S Serres, ...
Nature communications 8, 14254, 2017
82017
NMR-based metabolomics separates the distinct stages of disease in a chronic relapsing model of multiple sclerosis
AM Dickens, JR Larkin, BG Davis, JL Griffin, TDW Claridge, NR Sibson, ...
Journal of Neuroimmune Pharmacology 10 (3), 435-444, 2015
72015
Early diagnosis of brain metastases using a biofluids-metabolomics approach in mice
JR Larkin, AM Dickens, TDW Claridge, C Bristow, K Andreou, DC Anthony, ...
Theranostics 6 (12), 2161, 2016
52016
Are brain and heart tissue prone to the development of thiamine deficiency?
A Klooster, JR Larkin, J Wiersema-Buist, ROB Gans, PJ Thornalley, ...
Alcohol 47 (3), 215-221, 2013
52013
Thiamine in diabetic nephropathy: a novel treatment modality? Reply to Alkhalaf A, Kleefstra N, Groenier KH et al.
N Rabbani, SS Alam, S Riaz, JR Larkin, MW Akhtar, T Shafi, ...
Diabetologia 52 (6), 1214-1216, 2009
52009
Determination of an optimally sensitive and specific chemical exchange saturation transfer MRI quantification metric in relevant biological phantoms
KJ Ray, JR Larkin, YK Tee, AA Khrapitchev, G Karunanithy, M Barber, ...
NMR in Biomedicine 29 (11), 1624-1633, 2016
42016
13 C pyruvate transport across the blood-brain barrier in preclinical hyperpolarised MRI
JJ Miller, JT Grist, S Serres, JR Larkin, AZ Lau, K Ray, KR Fisher, ...
Scientific reports 8 (1), 15082, 2018
32018
Quantitative blood flow measurement in rat brain with multiphase arterial spin labelling magnetic resonance imaging
JR Larkin, MA Simard, AA Khrapitchev, JA Meakin, TW Okell, M Craig, ...
Journal of Cerebral Blood Flow & Metabolism, 0271678X18756218, 2018
32018
Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats
A Klooster, JR Larkin, A Adaikalakoteswari, ROB Gans, H van Goor, ...
NDT plus 2 (2), 182-183, 2008
32008
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