| Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes H Zhao, M Przybylska, IH Wu, J Zhang, C Siegel, S Komarnitsky, NS Yew, ... Diabetes 56 (5), 1210-1218, 2007 | 272 | 2007 |
| Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes H Zhao, M Przybylska, I Wu, J Cheng, CM Arbeeny, NS Yew, SH Cheng DIABETES 55, A107-A107, 2006 | 272 | 2006 |
| CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo NS Yew, H Zhao, M Przybylska, IH Wu, JD Tousignant, RK Scheule, ... Molecular Therapy 5 (6), 731-738, 2002 | 272 | 2002 |
| Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs NS Yew, H Zhao, IH Wu, A Song, JD Tousignant, M Przybylska, ... Molecular Therapy 1 (3), 255-262, 2000 | 272 | 2000 |
| Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice H Zhao, M Przybylska, I Wu, J Zhang, P Maniatis, J Pacheco, ... Hepatology 50 (1), 85-93, 2009 | 111 | 2009 |
| Contribution of Toll-like receptor 9 signaling to the acute inflammatory response to nonviral vectors H Zhao, H Hemmi, S Akira, SH Cheng, RK Scheule, NS Yew Molecular Therapy 9 (2), 241-248, 2004 | 100 | 2004 |
| CpG reduced plasmids and viral vectors NS Yew, H Zhao, JD Tousignant, SH Cheng US Patent 20,040,053,870, 2004 | 69 | 2004 |
| Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage Y Zhu, N Gumlaw, J Karman, H Zhao, J Zhang, JL Jiang, P Maniatis, ... Journal of Biological Chemistry 286 (17), 14787-14794, 2011 | 62 | 2011 |
| Increased hepatic insulin action in diet-induced obese mice following inhibition of glucosylceramide synthase NS Yew, H Zhao, EG Hong, IH Wu, M Przybylska, C Siegel, JA Shayman, ... PloS one 5 (6), e11239, 2010 | 48 | 2010 |
| Methods of Treating Fatty Liver Disease CM Arbeeny, SH Cheng, C Jiang, NS Yew, H Zhao US Patent App. 12/227,076, 2007 | 47* | 2007 |
| CpG reduced plasmids and viral vectors S Cheng, J Tousignant, N Yew, H Zhao | 45* | 2000 |
| DNA sequences in cationic lipid: pDNA-mediated systemic toxicities JD Tousignant, H Zhao, NS Yew, SH Cheng, SJ Eastman, RK Scheule Human gene therapy 14 (3), 203-214, 2003 | 44 | 2003 |
| Partial correction of the α‐galactosidase A deficiency and reduction of glycolipid storage in Fabry mice using synthetic vectors M Przybylska, I Wu, H Zhao, RJ Ziegler, JD Tousignant, RJ Desnick, ... The journal of gene medicine 6 (1), 85-92, 2004 | 36 | 2004 |
| Ligation of cytotoxic T lymphocyte antigen-4 to T cell receptor inhibits T cell activation and directs differentiation into Foxp3+ regulatory T cells J Karman, JL Jiang, N Gumlaw, H Zhao, J Campos-Rivera, J Sancho, ... Journal of Biological Chemistry 287 (14), 11098-11107, 2012 | 33 | 2012 |
| Requirements for effective inhibition of immunostimulatory CpG motifs by neutralizing motifs H ZHAO, SH CHENG, NS YEW Antisense and Nucleic Acid Drug Development 10 (5), 381-389, 2000 | 29 | 2000 |
| Methods of treating diabetes mellitus SH Cheng, NS Yew, RK Scheule, H Zhao US Patent 8,003,617, 2011 | 17 | 2011 |
| A Bispecific Protein Capable of Engaging CTLA-4 and MHCII Protects Non-Obese Diabetic Mice from Autoimmune Diabetes H Zhao, J Karman, JL Jiang, J Zhang, N Gumlaw, J Lydon, Q Zhou, H Qiu, ... PloS one 8 (5), e63530, 2013 | 8 | 2013 |
| Role of the toll-like 9 receptor in the acute inflammatory response to nonviral vectors H Zhao, I Huan, H Hemmi, SH Akira, RK Scheule, NS Yew MOLECULAR THERAPY 7 (5), S209-S209, 2003 | 2 | 2003 |
| Ligation of CTLA-4 to the TCR inhibits T cell activation and directs differentiation into Foxp3+ regulatory T cells Y Zhu, J Karman, JL Jiang, N Gumlaw, H Zhao, J Campos-Rivera, ... The Journal of Immunology 188, 72.2, 2012 | | 2012 |
| Genz-123346-Mediated Inhibition of Glycosphingolipid Synthesis As an Approach to Treat Type 2 Diabetes. H Zhao, N Yew, S Cheng Diabetes 56, 2007 | | 2007 |
