Charlotte L Scott
Charlotte L Scott
IRC, VIB, UGent, Belgium
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Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
CC Bain, A Bravo-Blas, CL Scott, E Gomez Perdiguero, F Geissmann, ...
Nature immunology 15 (10), 929-937, 2014
Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors
CC Bain, CL Scott, H Uronen-Hansson, S Gudjonsson, O Jansson, O Grip, ...
Mucosal immunology 6 (3), 498-510, 2013
Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species
M Guilliams, CA Dutertre, CL Scott, N McGovern, D Sichien, S Chakarov, ...
Immunity 45 (3), 669-684, 2016
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
CL Scott, F Zheng, P De Baetselier, L Martens, Y Saeys, S De Prijck, ...
Nature communications 7 (1), 10321, 2016
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
H Van Hove, L Martens, I Scheyltjens, K De Vlaminck, AR Pombo Antunes, ...
Nature neuroscience 22 (6), 1021-1035, 2019
Yolk sac macrophages, fetal liver, and adult monocytes can colonize an empty niche and develop into functional tissue-resident macrophages
L van de Laar, W Saelens, S De Prijck, L Martens, CL Scott, ...
Immunity 44 (4), 755-768, 2016
Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche
J Bonnardel, W T’Jonck, D Gaublomme, R Browaeys, CL Scott, L Martens, ...
Immunity 51 (4), 638-654. e9, 2019
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
M Guilliams, J Bonnardel, B Haest, B Vanderborght, C Wagner, ...
Cell 185 (2), 379-396. e38, 2022
Does niche competition determine the origin of tissue-resident macrophages?
M Guilliams, CL Scott
Nature Reviews Immunology 17 (7), 451-460, 2017
Intestinal CD103+ dendritic cells: master regulators of tolerance?
CL Scott, AM Aumeunier, AMI Mowat
Trends in immunology 32 (9), 412-419, 2011
Macrophages and lipid metabolism
A Remmerie, CL Scott
Cellular immunology 330, 27-42, 2018
Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver
A Remmerie, L Martens, T Thoné, A Castoldi, R Seurinck, B Pavie, ...
Immunity 53 (3), 641-657. e14, 2020
Type 2 innate lymphoid cells drive CD4+ Th2 cell responses
AS Mirchandani, AG Besnard, E Yip, C Scott, CC Bain, V Cerovic, ...
The Journal of Immunology 192 (5), 2442-2448, 2014
Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities
CC Bain, CA Hawley, H Garner, CL Scott, A Schridde, NJ Steers, M Mack, ...
Nature communications 7 (1), ncomms11852, 2016
IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively
D Sichien, CL Scott, L Martens, M Vanderkerken, S Van Gassen, ...
Immunity 45 (3), 626-640, 2016
Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells
V Cerovic, SA Houston, CL Scott, A Aumeunier, U Yrlid, AM Mowat, ...
Mucosal immunology 6 (1), 104-113, 2013
Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection
C Bosteels, K Neyt, M Vanheerswynghels, MJ van Helden, D Sichien, ...
Immunity 52 (6), 1039-1056. e9, 2020
The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
D Laoui, J Keirsse, Y Morias, E Van Overmeire, X Geeraerts, Y Elkrim, ...
Nature communications 7 (1), 13720, 2016
Development of conventional dendritic cells: from common bone marrow progenitors to multiple subsets in peripheral tissues
D Sichien, BN Lambrecht, M Guilliams, CL Scott
Mucosal immunology 10 (4), 831-844, 2017
The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages
CL Scott, W T’Jonck, L Martens, H Todorov, D Sichien, B Soen, ...
Immunity 49 (2), 312-325. e5, 2018
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