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David Paul
David Paul
MRC Laboratory of Molecular Biology
Verified email at mrc-lmb.cam.ac.uk - Homepage
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Cited by
Cited by
Year
SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF barrier in human brain organoids
L Pellegrini, A Albecka, DL Mallery, MJ Kellner, D Paul, AP Carter, ...
Cell stem cell 27 (6), 951-961. e5, 2020
4572020
Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion
G Papa, DL Mallery, A Albecka, LG Welch, J Cattin-Ortolá, J Luptak, ...
PLoS pathogens 17 (1), e1009246, 2021
2932021
Architecture and biogenesis of plus-strand RNA virus replication factories
D Paul, R Bartenschlager
World journal of virology 2 (2), 32, 2013
2882013
Hepatitis C virus RNA replication and assembly: living on the fat of the land
D Paul, V Madan, R Bartenschlager
Cell host & microbe 16 (5), 569-579, 2014
2742014
Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment
D Paul, S Hoppe, G Saher, J Krijnse-Locker, R Bartenschlager
Journal of virology 87 (19), 10612-10627, 2013
2682013
Flaviviridae replication organelles: oh, what a tangled web we weave
D Paul, R Bartenschlager
Annual review of virology 2, 289-310, 2015
1902015
Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus–induced membranous replication factories, independent of RNA replication
C Berger, I Romero-Brey, D Radujkovic, R Terreux, M Zayas, D Paul, ...
Gastroenterology 147 (5), 1094-1105. e25, 2014
1692014
NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes
D Paul, I Romero-Brey, J Gouttenoire, S Stoitsova, J Krijnse-Locker, ...
Journal of virology 85 (14), 6963-6976, 2011
1572011
Hepatitis C virus replication depends on endosomal cholesterol homeostasis
IK Stoeck, JY Lee, K Tabata, I Romero-Brey, D Paul, P Schult, V Lohmann, ...
Journal of virology 92 (1), 10.1128/jvi. 01196-17, 2018
1032018
Characterization of the mode of action of a potent dengue virus capsid inhibitor
P Scaturro, IML Trist, D Paul, A Kumar, EG Acosta, CM Byrd, R Jordan, ...
Journal of virology 88 (19), 11540-11555, 2014
992014
Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation
V Madan, D Paul, V Lohmann, R Bartenschlager
Gastroenterology 146 (5), 1361-1372. e9, 2014
952014
NS5A domain 1 and polyprotein cleavage kinetics are critical for induction of double-membrane vesicles associated with hepatitis C virus replication
I Romero-Brey, C Berger, S Kallis, A Kolovou, D Paul, V Lohmann, ...
MBio 6 (4), 10.1128/mbio. 00759-15, 2015
862015
Aminoterminal amphipathic α-helix AH1 of hepatitis C virus nonstructural protein 4B possesses a dual role in RNA replication and virus production
J Gouttenoire, R Montserret, D Paul, R Castillo, S Meister, ...
PLoS pathogens 10 (11), e1004501, 2014
602014
Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
K Tabata, V Prasad, D Paul, JY Lee, MT Pham, WI Twu, CJ Neufeldt, ...
Nature communications 12 (1), 7276, 2021
442021
Cell-free expression, purification, and membrane reconstitution for NMR studies of the nonstructural protein 4B from hepatitis C virus
ML Fogeron, V Jirasko, S Penzel, D Paul, R Montserret, C Danis, ...
Journal of biomolecular NMR 65, 87-98, 2016
272016
Wheat germ cell-free expression: two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins
ML Fogeron, A Badillo, V Jirasko, J Gouttenoire, D Paul, L Lancien, ...
Protein expression and purification 105, 39-46, 2015
272015
Glycine zipper motifs in hepatitis C virus nonstructural protein 4B are required for the establishment of viral replication organelles
D Paul, V Madan, O Ramirez, M Bencun, IK Stoeck, V Jirasko, ...
Journal of virology 92 (4), 10.1128/jvi. 01890-17, 2018
262018
Functional expression, purification, characterization, and membrane reconstitution of non-structural protein 2 from hepatitis C virus
ML Fogeron, D Paul, V Jirasko, R Montserret, D Lacabanne, J Molle, ...
Protein Expression and Purification 116, 1-6, 2015
152015
The predominant species of nonstructural protein 4B in hepatitis C virus-replicating cells is not palmitoylated
D Paul, R Bartenschlager, C McCormick
Journal of General Virology 96 (Pt_7), 1696-1701, 2015
112015
Cell surface protein aggregation triggers endocytosis to maintain plasma membrane proteostasis
D Paul, O Stern, Y Vallis, J Dhillon, A Buchanan, H McMahon
Nature Communications 14 (1), 947, 2023
102023
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