| Highly conserved homotrimer cavity formed by the SARS-CoV-2 spike glycoprotein: a novel binding site U Kalathiya, M Padariya, M Mayordomo, M Lisowska, J Nicholson, ... Journal of clinical medicine 9 (5), 1473, 2020 | 85 | 2020 |
| E3 ligase cIAP2 mediates downregulation of MRE11 and radiosensitization in response to HDAC inhibition in bladder cancer J Nicholson, SJ Jevons, B Groselj, S Ellermann, R Konietzny, M Kerr, ... Cancer research 77 (11), 3027-3039, 2017 | 47 | 2017 |
| Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity B Groselj, JL Ruan, H Scott, J Gorrill, J Nicholson, J Kelly, S Anbalagan, ... Molecular cancer therapeutics 17 (2), 381-392, 2018 | 41 | 2018 |
| Identification of a second N utlin‐3 responsive interaction site in the N‐terminal domain of MDM 2 using hydrogen/deuterium exchange mass spectrometry L Hernychova, P Man, C Verma, J Nicholson, CA Sharma, E Ruckova, ... Proteomics 13 (16), 2512-2525, 2013 | 37 | 2013 |
| Chemical states of the N-terminal “lid” of MDM2 regulate p53 binding: Simulations reveal complexities of modulation SG Dastidar, D Raghunathan, J Nicholson, TR Hupp, DP Lane, CS Verma Cell Cycle 10 (1), 82-89, 2011 | 37 | 2011 |
| The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors ER Dickinson, E Jurneczko, J Nicholson, TR Hupp, J Zawacka-Pankau, ... Frontiers in molecular biosciences 2, 39, 2015 | 36 | 2015 |
| An iTRAQ proteomics screen reveals the effects of the MDM2 binding ligand Nutlin-3 on cellular proteostasis J Nicholson, K Neelagandan, AS Huart, K Ball, MP Molloy, T Hupp Journal of proteome research 11 (11), 5464-5478, 2012 | 33 | 2012 |
| A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2 J Nicholson, A Scherl, L Way, EA Blackburn, MD Walkinshaw, KL Ball, ... Cellular signalling 26 (6), 1243-1257, 2014 | 31 | 2014 |
| Quantitative mass spectrometry for colorectal cancer proteomics J Martínez‐Aguilar, J Chik, J Nicholson, C Semaan, MJ McKay, MP Molloy PROTEOMICS–Clinical Applications 7 (1-2), 42-54, 2013 | 29 | 2013 |
| p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation S Kilgas, AN Singh, S Paillas, CK Then, I Torrecilla, J Nicholson, ... Cell reports 35 (8), 2021 | 27 | 2021 |
| The molecular dynamics of MDM2 J Nicholson, TR Hupp Cell Cycle 9 (10), 1878-1881, 2010 | 23 | 2010 |
| Rearrangement of mitochondrial pyruvate dehydrogenase subunit dihydrolipoamide dehydrogenase protein–protein interactions by the MDM2 ligand nutlin‐3 L Way, J Faktor, P Dvorakova, J Nicholson, B Vojtesek, D Graham, KL Ball, ... Proteomics 16 (17), 2327-2344, 2016 | 19 | 2016 |
| The anterior gradient-2 pathway as a model for developing peptide-aptamer anti-cancer drug leads that stimulate p53 function A Fourtouna, E Murray, J Nicholson, MM Maslon, LY Pang, DTF Dryden, ... Current Chemical Biology 3 (2), 124-137, 2009 | 18 | 2009 |
| No additional prognostic value for MRE11 in squamous cell carcinomas of the anus treated with chemo-radiotherapy AK Walker, C Kartsonaki, E Collantes, J Nicholson, DC Gilbert, AE Kiltie British journal of cancer 117 (3), 322-325, 2017 | 6 | 2017 |
| Arsenic biosenseor: a step further C French, J Nicholson, F Bizzari, J Aleksic, Y Cai, SL Seshasayee, ... BMC Systems Biology 1, 1-2, 2007 | 4 | 2007 |
| Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site (preprint) U Kalathiya, M Padariya, M Mayordomo, M Lisowska, J Nicholson, ... | | 2020 |
| An Integrative “Omics” Approach, for Identification of Bona Fides PLK1 Associated Biomarker in Esophageal Adenocarcinoma N Bibi, S Rashid, J Nicholson, M Malloy, R O'Neill, D Blake, T Hupp Current cancer drug targets 19 (9), 742-755, 2019 | | 2019 |
| Mo1856 Mutation of TP53 Creates an Opportunity for Synthetic Lethality in Esophageal Adenocarcinoma JR O'Neill, CAJ Ong, J Nicholson, R Nenutil, B Vojtesek, R Fitzgerald, ... Gastroenterology 5 (144), S-676, 2013 | | 2013 |
| Proteomic investigation of the MDM2 interactome and linear motif interactions J Nicholson The University of Edinburgh, 2011 | | 2011 |
