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Sushama Sivakumar
Sushama Sivakumar
Verified email at utsouthwestern.edu
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Cited by
Year
Noncoding RNA NORAD regulates genomic stability by sequestering PUMILIO proteins
S Lee, F Kopp, TC Chang, A Sataluri, B Chen, S Sivakumar, H Yu, Y Xie, ...
Cell 164 (1), 69-80, 2016
8292016
Spatiotemporal regulation of the anaphase-promoting complex in mitosis
S Sivakumar, GJ Gorbsky
Nature reviews Molecular cell biology 16 (2), 82-94, 2015
3042015
Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited
TA Potapova, S Sivakumar, JN Flynn, R Li, GJ Gorbsky
Molecular biology of the cell 22 (8), 1191-1206, 2011
1952011
Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis
JR Daum, JD Wren, JJ Daniel, S Sivakumar, JN McAvoy, TA Potapova, ...
Current Biology 19 (17), 1467-1472, 2009
1952009
Cohesion fatigue induces chromatid separation in cells delayed at metaphase
JR Daum, TA Potapova, S Sivakumar, JJ Daniel, JN Flynn, S Rankin, ...
Current biology 21 (12), 1018-1024, 2011
1722011
The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores
S Sivakumar, PŁ Janczyk, Q Qu, CA Brautigam, PT Stukenberg, H Yu, ...
Elife 5, e12902, 2016
942016
PUMILIO hyperactivity drives premature aging of Norad-deficient mice
JTM Florian Kopp, Mahmoud M Elguindy, Mehmet E Yalvac, He Zhang, Beibei Chen ...
elife 8 (10.7554/eLife.42650), 2019
862019
Ska3 phosphorylated by Cdk1 binds Ndc80 and recruits Ska to kinetochores to promote mitotic progression
Q Zhang, S Sivakumar, Y Chen, H Gao, L Yang, Z Yuan, H Yu, H Liu
Current Biology 27 (10), 1477-1484. e4, 2017
852017
The spindle and kinetochore–associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit
S Sivakumar, JR Daum, AR Tipton, S Rankin, GJ Gorbsky
Molecular biology of the cell 25 (5), 594-605, 2014
752014
Phosphatase-regulated recruitment of the spindle-and kinetochore-associated (Ska) complex to kinetochores
S Sivakumar, GJ Gorbsky
Biology open 6 (11), 1672-1679, 2017
272017
Live-cell fluorescence imaging for phenotypic analysis of mitosis
S Sivakumar, JR Daum, GJ Gorbsky
Cell Cycle Control: Mechanisms and Protocols, 549-562, 2014
212014
TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
S Sivakumar, S Qi, N Cheng, AA Sathe, M Kanchwala, A Kumar, ...
Cell reports 38 (7), 2022
172022
CHD-associated enhancers shape human cardiomyocyte lineage commitment
DA Armendariz, SC Goetsch, A Sundarrajan, S Sivakumar, Y Wang, S Xie, ...
Elife 12, e86206, 2023
52023
Collaborations: Pros and Cons Bethesda
JF Sushama Sivakumar
MD: The American Society for Cell Biology (ASCB), 41032-2, 2016
22016
CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
S Qi, S Sivakumar, H Yu
STAR protocols 3 (4), 101682, 2022
12022
Live fluorescence imaging of chromosome segregation in cultured cells
JR Daum, CO DuBose, S Sivakumar, GJ Gorbsky
Mitosis: Methods and Protocols, 61-86, 2022
2022
The Ska complex recruits Protein Phosphatase 1 to the kinetochore and promotes the metaphase-anaphase transition.
S Sivakumar, P Janczyk, Q Qu, P Stukenberg, H Yu, GJ Gorbsky
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
Metaphase delays lead to chromosome cohesion fatigue, a novel mechanism underlying chromosome instability and aneuploidy
JR Daum, S Sivakumar, AR Tipton, MW Davidson, GJ Gorbsky
Cancer Research 74 (19_Supplement), 5083-5083, 2014
2014
The Role of the Spindle and Kinetochore Associated (SKA) Protein Complex in Mitotic Progression
S Sivakumar
University of Oklahoma, 2013
2013
Kinetochore Association of the Ska Complex Enhances APC/C-Mediated Degradation to Promote Anaphase Onset and Mitotic Exit
S Sivakumar, JR Daum, AR Tipton, S Rankin, GJ Gorbsky
MOLECULAR BIOLOGY OF THE CELL 24, 2013
2013
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