Hiroshi Nishimasu
Hiroshi Nishimasu
Verified email at bs.s.u-tokyo.ac.jp
Cited by
Cited by
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ...
Nature 517 (7536), 583-588, 2015
Crystal structure of Cas9 in complex with guide RNA and target DNA
H Nishimasu, FA Ran, PD Hsu, S Konermann, SI Shehata, N Dohmae, ...
Cell 156 (5), 935-949, 2014
Engineered CRISPR-Cas9 nuclease with expanded targeting space
H Nishimasu, X Shi, S Ishiguro, L Gao, S Hirano, S Okazaki, T Noda, ...
Science 361 (6408), 1259-1262, 2018
Crystal structure of Cpf1 in complex with guide RNA and target DNA
T Yamano, H Nishimasu, B Zetsche, H Hirano, IM Slaymaker, Y Li, ...
Cell 165 (4), 949-962, 2016
Crystal structure of Staphylococcus aureus Cas9
H Nishimasu, L Cong, WX Yan, FA Ran, B Zetsche, Y Li, A Kurabayashi, ...
Cell 162 (5), 1113-1126, 2015
Structure and function of Zucchini endoribonuclease in piRNA biogenesis
H Nishimasu, H Ishizu, K Saito, S Fukuhara, MK Kamatani, L Bonnefond, ...
Nature 491 (7423), 284-287, 2012
Engineered Cpf1 variants with altered PAM specificities
L Gao, DBT Cox, WX Yan, JC Manteiga, MW Schneider, T Yamano, ...
Nature biotechnology 35 (8), 789-792, 2017
Structure and engineering of Francisella novicida Cas9
H Hirano, JS Gootenberg, T Horii, OO Abudayyeh, M Kimura, PD Hsu, ...
Cell 164 (5), 950-961, 2016
Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
H Nishimasu, S Okudaira, K Hama, E Mihara, N Dohmae, A Inoue, ...
Nature structural & molecular biology 18 (2), 205-212, 2011
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF‐κB regulation
F Tokunaga, H Nishimasu, R Ishitani, E Goto, T Noguchi, K Mio, K Kamei, ...
The EMBO journal 31 (19), 3856-3870, 2012
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase
S Akichika, S Hirano, Y Shichino, T Suzuki, H Nishimasu, R Ishitani, ...
Science 363 (6423), 2019
Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy
M Shibata, H Nishimasu, N Kodera, S Hirano, T Ando, T Uchihashi, ...
Nature communications 8 (1), 1-9, 2017
Structural basis for the canonical and non-canonical PAM recognition by CRISPR-Cpf1
T Yamano, B Zetsche, R Ishitani, F Zhang, H Nishimasu, O Nureki
Molecular cell 67 (4), 633-645. e3, 2017
Structural basis for the altered PAM specificities of engineered CRISPR-Cas9
S Hirano, H Nishimasu, R Ishitani, O Nureki
Molecular cell 61 (6), 886-894, 2016
Crystal structure of the minimal Cas9 from Campylobacter jejuni reveals the molecular diversity in the CRISPR-Cas9 systems
M Yamada, Y Watanabe, JS Gootenberg, H Hirano, FA Ran, T Nakane, ...
Molecular cell 65 (6), 1109-1121. e3, 2017
Genome editing in plants by engineered CRISPR–Cas9 recognizing NG PAM
M Endo, M Mikami, A Endo, H Kaya, T Itoh, H Nishimasu, O Nureki, S Toki
Nature plants 5 (1), 14-17, 2019
Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling
K Kato, H Nishimasu, S Okudaira, E Mihara, R Ishitani, J Takagi, J Aoki, ...
Proceedings of the National Academy of Sciences 109 (42), 16876-16881, 2012
Structural basis for potent inhibition of SIRT2 deacetylase by a macrocyclic peptide inducing dynamic structural change
K Yamagata, Y Goto, H Nishimasu, J Morimoto, R Ishitani, N Dohmae, ...
Structure 22 (2), 345-352, 2014
Crystal structure of silkworm PIWI-clade Argonaute Siwi bound to piRNA
N Matsumoto, H Nishimasu, K Sakakibara, KM Nishida, T Hirano, ...
Cell 167 (2), 484-497. e9, 2016
Structures and mechanisms of CRISPR RNA-guided effector nucleases
H Nishimasu, O Nureki
Current opinion in structural biology 43, 68-78, 2017
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