Blake Wiedenheft
Blake Wiedenheft
Assistant Professor Microbiology and Immunology, Montana State University
Verified email at - Homepage
Cited by
Cited by
Unravelling the structural and mechanistic basis of CRISPR–Cas systems
J Van Der Oost, ER Westra, RN Jackson, B Wiedenheft
Nature Reviews Microbiology 12 (7), 479-492, 2014
RNA-guided genetic silencing systems in bacteria and archaea
B Wiedenheft, SH Sternberg, JA Doudna
Nature 482 (7385), 331-338, 2012
Sequence-and structure-specific RNA processing by a CRISPR endonuclease
RE Haurwitz, M Jinek, B Wiedenheft, K Zhou, JA Doudna
Science 329 (5997), 1355-1358, 2010
CRISPR-mediated adaptive immune systems in bacteria and archaea
R Sorek, CM Lawrence, B Wiedenheft
Annual review of biochemistry 82, 237-266, 2013
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions
B Wiedenheft, E van Duijn, JB Bultema, SP Waghmare, K Zhou, ...
Proceedings of the National Academy of Sciences 108 (25), 10092-10097, 2011
Structural basis for CRISPR RNA-guided DNA recognition by Cascade
MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ...
Nature structural & molecular biology 18 (5), 529, 2011
Structures of the RNA-guided surveillance complex from a bacterial immune system
B Wiedenheft, GC Lander, K Zhou, MM Jore, SJJ Brouns, J van der Oost, ...
Nature 477 (7365), 486-489, 2011
Mechanism of foreign DNA selection in a bacterial adaptive immune system
DG Sashital, B Wiedenheft, JA Doudna
Molecular cell 46 (5), 606-615, 2012
Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins
J Bondy-Denomy, B Garcia, S Strum, M Du, MCF Rollins, ...
Nature 526 (7571), 136-139, 2015
Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense
B Wiedenheft, K Zhou, M Jinek, SM Coyle, W Ma, JA Doudna
Structure 17 (6), 904-912, 2009
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli
RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ...
Science 345 (6203), 1473-1479, 2014
Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition
ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ...
PLoS Genet 9 (9), e1003742, 2013
Viruses from extreme thermal environments
G Rice, K Stedman, J Snyder, B Wiedenheft, D Willits, S Brumfield, ...
Proceedings of the National Academy of Sciences 98 (23), 13341-13345, 2001
Endoribonuclease compositions and methods of use thereof
RE Haurwitz, JA Doudna, B Wiedenheft, M Jinek
US Patent 9,115,348, 2015
Methods of generating nucleic acid fragments
B Wiedenheft, K Zhou, JA Doudna
US Patent 10,087,431, 2018
Temporal detection and phylogenetic assessment of SARS-CoV-2 in municipal wastewater
A Nemudryi, A Nemudraia, T Wiegand, K Surya, M Buyukyoruk, C Cicha, ...
Cell Reports Medicine 1 (6), 100098, 2020
Surveillance and processing of foreign DNA by the Escherichia coli CRISPR-Cas system
S Redding, SH Sternberg, M Marshall, B Gibb, P Bhat, CK Guegler, ...
Cell 163 (4), 854-865, 2015
Comparative genomic analysis of hyperthermophilic archaeal Fuselloviridae viruses
B Wiedenheft, K Stedman, F Roberto, D Willits, AK Gleske, L Zoeller, ...
Journal of Virology 78 (4), 1954-1961, 2004
An archaeal antioxidant: characterization of a Dps-like protein from Sulfolobus solfataricus
B Wiedenheft, J Mosolf, D Willits, M Yeager, KA Dryden, M Young, ...
Proceedings of the National Academy of Sciences 102 (30), 10551-10556, 2005
Structure reveals mechanisms of viral suppressors that intercept a CRISPR RNA-guided surveillance complex
S Chowdhury, J Carter, MCF Rollins, SM Golden, RN Jackson, ...
Cell 169 (1), 47-57. e11, 2017
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